Thermus thermophilus JL-18: TtJL18_1121
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Entry
TtJL18_1121 CDS
T02009
Name
(GenBank) pyruvate dehydrogenase E1 component, alpha subunit
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
ttl
Thermus thermophilus JL-18
Pathway
ttl00010
Glycolysis / Gluconeogenesis
ttl00020
Citrate cycle (TCA cycle)
ttl00620
Pyruvate metabolism
ttl00785
Lipoic acid metabolism
ttl01100
Metabolic pathways
ttl01110
Biosynthesis of secondary metabolites
ttl01120
Microbial metabolism in diverse environments
ttl01200
Carbon metabolism
ttl01210
2-Oxocarboxylic acid metabolism
Module
ttl_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ttl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
TtJL18_1121
00020 Citrate cycle (TCA cycle)
TtJL18_1121
00620 Pyruvate metabolism
TtJL18_1121
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
TtJL18_1121
Enzymes [BR:
ttl01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
TtJL18_1121
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GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
HTH_41
Motif
Other DBs
NCBI-ProteinID:
AFH39015
UniProt:
H9ZRQ5
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Position
1033960..1035000
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AA seq
346 aa
AA seq
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MKPKVVRYLDKGEFPLAEEEALRLYRAMRRARFFDEKALTLQRQGRLGVYPPFMGQEAAQ
VGVALALEEKDWVVPSYRESAMLLAKGLPIHTLILYWRAHPAGWRFPEEVRAVNPYIPIA
TQIPQAVGLALAGRYRGEDWVVATSIGDGGTSEGDFHEGLNFAAVFGAPVVFLVQNNGYA
ISVPKSRQMKVDYVARRAEGYGMPGVVVDGNDAFAVYLEAKKAVERARKGEGPTLLEALT
YRLAPHTTSDDPSRYRSKEEEEAWRAKDPILRLRKALEGRGLWDEEAEKALLLELEEEFQ
RELALADEAPEPSPEEIVEHVYAEMGPDQRRAWEALRRGLHVEEVE
NT seq
1041 nt
NT seq
+upstream
nt +downstream
nt
gtgaagccgaaggtggtgcggtatctggataagggggagttccccctagcggaggaagaa
gccctaaggctctaccgggccatgcgtcgggcccggttttttgacgagaaggccctcacc
ctccagcgccagggacggctcggggtctaccctcccttcatgggccaggaggcggcccag
gtgggggtggccctggccctggaggagaaggactgggtcgtcccttcctaccgggaaagc
gccatgctcctcgccaaggggcttcccatccacaccctgatcctctactggcgggcccac
cccgcgggctggcgcttccccgaggaggtcagggcggtgaacccctatatccccatcgcc
acccagatcccccaggcggtggggctcgccctggccgggcggtaccggggggaggactgg
gtggtggccacctccatcggggacggggggacgagcgagggagacttccacgaggggctg
aacttcgccgcggtcttcggcgcccccgtggtcttcctggtgcagaacaacggctacgcc
atcagcgttcccaaaagccgccagatgaaggtggactacgtggcgaggcgggccgagggg
tacgggatgcccggggtggtggtggacgggaacgacgccttcgccgtgtacctcgaggcc
aagaaggcggtggaacgggccaggaagggggaaggccccaccctcctcgaggccctcacc
taccgcctcgccccccacaccacctccgacgacccctcccgctaccgcagcaaagaggaa
gaggaggcctggcgggccaaggacccgatcctccgcctgcggaaggccctggaggggcgg
ggcctttgggacgaggaggcggaaaaggcgcttcttcttgagcttgaggaggagttccag
agggagctcgccctggccgacgaagcccccgagcccagccccgaggagatcgtggagcac
gtctacgccgagatgggccccgaccagaggcgggcctgggaagcgctcaggcgaggcctt
cacgtggaggaggtggagtga
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