Tupaia chinensis (Chinese tree shrew): 102482570 Help Entry 102482570         CDS       T02978                                  Symbol TH Name (RefSeq) tyrosine hydroxylase   KO K00501   tyrosine 3-monooxygenase [EC:1.14.16.2] Organism tup  Tupaia chinensis (Chinese tree shrew) Pathway tup00350   Tyrosine metabolism tup00790   Folate biosynthesis tup01100   Metabolic pathways tup04728   Dopaminergic synapse tup04917   Prolactin signaling pathway tup05012   Parkinson disease tup05030   Cocaine addiction tup05031   Amphetamine addiction tup05034   Alcoholism Module tup_M00042   Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline Brite KEGG Orthology (KO) [BR:tup00001]  09100 Metabolism   09105 Amino acid metabolism    00350 Tyrosine metabolism     102482570 (TH)   09108 Metabolism of cofactors and vitamins    00790 Folate biosynthesis     102482570 (TH)  09150 Organismal Systems   09152 Endocrine system    04917 Prolactin signaling pathway     102482570 (TH)   09156 Nervous system    04728 Dopaminergic synapse     102482570 (TH)  09160 Human Diseases   09164 Neurodegenerative disease    05012 Parkinson disease     102482570 (TH)   09165 Substance dependence    05030 Cocaine addiction     102482570 (TH)    05031 Amphetamine addiction     102482570 (TH)    05034 Alcoholism     102482570 (TH) Enzymes [BR:tup01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor     1.14.16.2  tyrosine 3-monooxygenase      102482570 (TH) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Biopterin_H TH_ACT TOH_N LTP_2 Motif Other DBs NCBI-GeneID:  102482570 NCBI-ProteinID:  XP_006141133 LinkDB All DBs Position Un AA seq 497 aa AA seqDB search MPTPNAATPQPKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREAAVAAAAAAA SSEPGDPLETVTFEEKDGKAVVNLLFSLKGSKPSSLSRAVKVFETFEAKIHHLETRPTQR PRAGAPHLEYFVRCEVPSRDLATLLSSVRRVTEDLRSAGEDKVPWFPRKVSELDKCHHLV TKFDPDLDLDHPGFSDQAYRQRRKLIAEIAFQYKHGDPIPRVEYTAEEIATWKEVYTTLK SLYATHACREHLEAFELLERFSGYQEDNIPQLEDVSRFLKERTGFQLRPVAGLLSARDFL ASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASD EEIEKLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHSLSEEPEIRAFDPEAAAVQ PYQDQTYQPVYFVSESFSDAKDKLRGYASRIQRPFSVKFDPYTLAVDVLDSPRTIRRSLE GVQDELHTLAHALSAIG NT seq 1494 nt NT seq  +upstreamnt  +downstreamnt atgcccacccccaacgctgccacgccgcagcccaagggcttccgaagggctgtgtccgag ctggacgccaagcaggctgaggccatcatgtccccgaggttcatcgggcggcggcagagc ctcattgaagatgcacgcaaggagcgggaggcggcggtggcggccgcagcagcagcggcc tcctcggagcccggggaccccctggagacagtgacttttgaggagaaagatggaaaggcc gtggtgaatctgctcttctccctgaagggctccaagccctcgtcactgtctcgcgctgtg aaggtgtttgagacgtttgaagccaaaatccaccacctggagacccggcccacccagagg ccacgggcgggggctccccatctggagtactttgttcgctgtgaggtgcccagcagggac ctggccaccctgctcagctctgtgcgtcgggtgacagaggacttgcgcagtgctggggag gacaaggtcccctggttcccaagaaaagtgtcagagctggacaagtgtcaccacctggtc accaagtttgatcccgacctggacttggaccatccgggcttctcggaccaggcgtaccgg cagcgcagaaagctgattgccgaaatagccttccagtacaagcatggtgacccgattccc cgtgttgagtacacagctgaggagatcgccacctggaaggaagtctacaccacgctgaag agcctttatgccacccatgcctgccgggagcacctcgaggcttttgagctgttggagcgc ttcagcggctaccaggaggacaacatcccacagctggaggacgtctcccgcttcctgaag gagcggacgggcttccagctgcgacctgtggccggcctgttgtctgcccgggacttcctg gccagcctggccttccgtgtgttccagtgtacccagtacatccgccatgcatcctcgccc atgcattctcccgagccggactgctgccatgagctgctgggacacgtgcccatgctggct gaccgcacatttgcccagttctcccaggacatcggccttgcgtccctgggggcctcggac gaggaaattgagaagctgtccacgctgtactggttcacggtggagttcgggctgtgcaag cagaacggggaggtgaaggcctacggtgcaggactgctgtcctcctatggggagctcctg cactccctgtctgaggagccagagatcagagccttcgaccccgaggccgcggccgtgcag ccctaccaagaccagacctaccagccagtctacttcgtgtctgagagttttagtgatgcc aaagacaagctcaggggctacgcctcgcgcatccagcgtcccttctccgtgaagttcgac ccgtacacgctggccgtcgacgtgctggacagtccccgcaccatccggcgctccctagaa ggtgtccaggacgagctgcacaccctggcccacgcgctgagtgccattggctag

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