Tupaia chinensis (Chinese tree shrew): 102502588
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Entry
102502588 CDS
T02978
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase (lipoamide) alpha 1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
tup
Tupaia chinensis (Chinese tree shrew)
Pathway
tup00010
Glycolysis / Gluconeogenesis
tup00020
Citrate cycle (TCA cycle)
tup00620
Pyruvate metabolism
tup00785
Lipoic acid metabolism
tup01100
Metabolic pathways
tup01200
Carbon metabolism
tup01210
2-Oxocarboxylic acid metabolism
tup04066
HIF-1 signaling pathway
tup04922
Glucagon signaling pathway
tup05230
Central carbon metabolism in cancer
tup05415
Diabetic cardiomyopathy
Module
tup_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
tup00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
102502588 (PDHA1)
00020 Citrate cycle (TCA cycle)
102502588 (PDHA1)
00620 Pyruvate metabolism
102502588 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
102502588 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
102502588 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
102502588 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
102502588 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
102502588 (PDHA1)
Enzymes [BR:
tup01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
102502588 (PDHA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
102502588
NCBI-ProteinID:
XP_014446856
LinkDB
All DBs
Position
Un
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPATTVLTRED
GLRYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVRQILAELTGRKGGCARGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLTSVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgcttgccgccgtctctcgcgttttatctggcgctgcccagaagccggca
agcagagtcttggtggcttcccgtaattttgcaaatgatgctacgtttgaaattaagaaa
tgtgaccttcaccgcctggaagaaggccctcctgccacgacagtgctcaccagggaggat
ggactcagatactacaggatgatgcagactgtgcgccgaatggagctgaaggcagatcag
ctctataagcagaagattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgc
tgtgtgggcctggaggccggcataaatcccacagaccacctcatcacagcctatcgggct
catggctttaccttcactcgtggcctttcagtccgacaaattctcgcagagcttacagga
cggaaaggaggttgtgccagagggaaaggaggatccatgcatatgtatgccaagaacttc
tacgggggcaatggaatcgttggggctcaggtgcccctgggagctgggattgctctggcc
tgtaagtataatggaaaagacgaagtctgtttgactttatatggtgacggtgctgctaat
cagggtcagatattcgaagcttacaacatggcagctctgtggaaattgccttgcattttc
atctgtgagaataaccgctatggaatgggaacatctgtggagagagcggcggccagcaca
gattactacaagagaggcgactttattcctgggctgagggttgatggaatggatatcctg
tgtgtccgagaggcgacaaggtttgcagctgcctactgtagatctgggaaggggcccatc
ctcatggagctgcagacttaccgttaccacggacacagcatgagtgaccctggagtcagt
tatcgtacacgagaagaaattcaggaagtaagaagtaagagtgaccctattatgcttctc
aaggatagaatggtgaacagcaatctcaccagtgttgaagaattaaaggaaattgatgtt
gaagtgagaaaagaaattgaagatgccgcccagtttgccacggctgatcctgagccacct
ttggaggaactaggctatcacatctactccagcgatcccccttttgaagttcgtggcgcc
aaccagtggatcaagtttaagtcggtcagttaa
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