Thermoproteus uzoniensis: TUZN_1027
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Entry
TUZN_1027 CDS
T01460
Name
(GenBank) Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, alpha subunit
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
tuz
Thermoproteus uzoniensis
Pathway
tuz00010
Glycolysis / Gluconeogenesis
tuz00020
Citrate cycle (TCA cycle)
tuz00620
Pyruvate metabolism
tuz00785
Lipoic acid metabolism
tuz01100
Metabolic pathways
tuz01110
Biosynthesis of secondary metabolites
tuz01120
Microbial metabolism in diverse environments
tuz01200
Carbon metabolism
tuz01210
2-Oxocarboxylic acid metabolism
Module
tuz_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
tuz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
TUZN_1027
00020 Citrate cycle (TCA cycle)
TUZN_1027
00620 Pyruvate metabolism
TUZN_1027
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
TUZN_1027
Enzymes [BR:
tuz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
TUZN_1027
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
AEA12508
UniProt:
F2L6B2
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Position
900324..901442
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AA seq
372 aa
AA seq
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MLETNLEIPRQYRTEVKQPQIFRVLGQDGEPNEAYEIGYKPTEGELAKAYRWMVVGRTLD
KYALMYHRMGKVRSTYGPHEGHEAADAGTALALRPEDWVAPHYRNLTLVIARGVPLEVIW
AKFFAKSGDPDKGRNLTIEWGGFKKWRILSIGAPIGHQYVYAAGFAYALRYMKRDEVVAA
YIGDGGTSTGGFHAGLNFAGVYKVPAAFFIYNNQYAISMPVARQTAVERLATKAAAYGIE
GVSADGMDLLAVVKTAKWAVEKARRGEPALVEYVMYRFGPHTTADDPLTRYRDQKEVEEW
RRWDPLARLERFLIRSGIYSESDVRTIWEEAEREVKEAAKAAEAMPDVPVEEAVRDVYSF
VPKSLQEWLGEL
NT seq
1119 nt
NT seq
+upstream
nt +downstream
nt
gtgttggaaacaaatttagaaattcctagacagtatagaacagaagttaaacagccgcag
atcttcagagtgctcggccaagacggcgagcccaacgaggcctacgagataggctataag
ccgaccgagggcgagctggccaaggcgtataggtggatggtggtcggcaggactctcgac
aagtacgccttgatgtaccacaggatgggcaaggtgaggtccacctacgggcctcacgag
gggcacgaggccgcggacgccggcacggcgctggcgctcaggccggaggactgggtggcg
ccgcactacaggaacttgactctcgtcatcgcccgcggcgtcccgctggaggttatatgg
gccaagttcttcgccaagtccggcgaccccgacaagggcaggaacctcacgatcgagtgg
ggcggcttcaagaaatggcgcattctgtcgattggcgcccctataggccaccagtacgtg
tacgcggctgggttcgcctacgcgctgaggtatatgaagagggacgaggtggtggcggcc
tacatcggcgacggcggcacctcgaccggcggcttccacgcaggcttgaacttcgccggg
gtctacaaggtccccgcggcgttcttcatctacaacaaccaatacgccatatccatgccg
gtggccagacagaccgcggtggagcggctggcgaccaaggcggcggcatacgggatagag
ggcgtctcggccgacggtatggatctcctggcggttgtcaagacggccaaatgggcggtc
gagaaggcgaggcgcggggagccagcgttggtggagtacgtgatgtaccgcttcggcccc
cacaccacggccgacgatcccctgaccaggtatagggaccagaaggaggttgaggagtgg
aggcgttgggatcctctggccaggctggagcgcttcctgataaggtcggggatatacagc
gagagcgacgtgaggactatctgggaggaggcggagagggaggtcaaggaggccgccaag
gcggcggaggcaatgcccgacgtgcccgtcgaggaggcggtaagggacgtctacagcttc
gtccccaagtcgctccaggaatggctgggggagctatga
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