Tachysurus vachellii: 132847025
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Entry
132847025 CDS
T09596
Symbol
gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
tvc
Tachysurus vachellii
Pathway
tvc00270
Cysteine and methionine metabolism
tvc00480
Glutathione metabolism
tvc01100
Metabolic pathways
tvc01240
Biosynthesis of cofactors
tvc04216
Ferroptosis
Module
tvc_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
tvc00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
132847025 (gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
132847025 (gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
132847025 (gclc)
Enzymes [BR:
tvc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
132847025 (gclc)
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
132847025
NCBI-ProteinID:
XP_060727883
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Position
6:6367376..6377053
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AA seq
631 aa
AA seq
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MGLLSQGSPLNWTETKKYADHVRKHGIVQFLNIYNKVKDRQKDVLKWGDEVEYMLVELDE
KNEKARVVLNGSKVLETLQEKGEKVNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMDKRRKEASSVLKEDDTICTITSFPRLGCPGFTKPEHRPTPVEKGVSKSLFFPDEAI
NRHPRFSTLTRNIRHRRGEKVVINVPIFKDQNTPSPFVETFPEDDGEAASAARPDHIYMD
AMGFGMGNCCLQVTFQACSISEARYLYDQLATFCPILMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTREERGLEPLKNNKFRIHKSRYDSIDSYLSFCGEKYNDIELTIDVEIYNQLL
DAGIDKLLAQHIAHLFIRDPLSLFEEKIHLDDENESDHFENLQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENAAYVVFIVLLTRVILSYKLDFLIPLSKVDDNMKVAQKRNAV
QEGMFYFRKDIFKGCSPLFDSATTAAQNGVETDGNHEEYTLMSIDTIINGKEGVFQGLVP
ILNYYLANMEVDVDTRCTILNYLKLIKKRASGELMTMAKWMREFVSKHPQYKNDSVITDK
INYDLLCKCDRIAKGEEQCPELIGEPVKRRK
NT seq
1896 nt
NT seq
+upstream
nt +downstream
nt
atgggcttgttgtctcagggctccccgcttaactggactgaaaccaagaaatatgccgac
catgtcagaaagcacggcattgtgcagttcctcaacatctacaacaaggtgaaggaccgg
cagaaggatgtgctaaagtggggcgacgaggtagagtacatgttggtggaactggatgag
aaaaatgaaaaggcccgtgtggttctgaacgggagcaaagtgttggagacactgcaggaa
aagggggaaaaggtcaaccccaaccatccaaccctgtggagaccagagtatggcagctac
atgattgagggcactccaggacagccttacggcgggacgatgtccgagttcaacacagtc
gaagacaacatggacaaacggaggaaggaggcgtcgtccgtgctcaaagaggacgacact
atctgcactatcacatcgttccccaggttagggtgcccgggattcacaaagccagaacac
aggcctacacctgttgaaaaaggagtgagcaagtccctcttctttcctgatgaggccatc
aatagacatccccgattcagcactttgacccggaacattcgtcacagaaggggggaaaag
gtggtgatcaacgtaccgatttttaaagatcaaaacacaccaagtccatttgtggagacg
tttcccgaggacgacggggaggcggcaagtgcagctcggcccgatcacatctacatggac
gccatgggcttcggaatgggaaactgctgtctgcaggtcacatttcaagcttgcagcatc
agtgaggctcgatacctctatgaccagctggccacattctgccccatactgatggccctc
agtgctgcttctcccttctatcgtggctacgtgtctgatatcgactgtcgctggggcgtt
atctcggcctccgtggacgacaggactcgggaagaacgagggctggagcctctgaaaaac
aacaaattcaggatccacaagtcaagatatgactccattgacagctacctttctttttgt
ggggaaaaatacaacgacatcgaactgacaatagatgttgaaatctacaatcagctcctt
gacgcagggattgacaaattactggcccagcacatcgcccacctctttatccgtgacccg
ctgtcgctcttcgaggaaaagattcatttggacgatgagaacgaatcggaccactttgag
aatcttcagtcaaccaactggcagaccatgaggttcaaaccacctcctccgaactctgac
attggatggagagtcgagttccggcccatggaggttcagttaactgactttgagaacgcc
gcatacgttgtgttcattgttctccttactcgagtcatcctttcctacaagttagacttc
ctcattcccttgtcgaaggtggacgacaacatgaaagttgcccagaaaagaaacgcagtc
caagaaggcatgttttacttcaggaaggacatctttaaaggctgcagcccattgtttgac
tcggccaccacagccgcccaaaatggcgtagagaccgacggcaaccatgaggaatacaca
ctgatgagcatcgacacaatcattaacggcaaggagggagtgttccagggactcgtacca
attctgaattactacctggcgaacatggaggtcgatgtagacacacgctgcaccatcctg
aactacctcaaactcattaagaagcgagcatcgggagaactgatgaccatggcaaagtgg
atgagggaatttgtttccaagcatccacagtacaagaacgacagcgtgatcacagacaaa
ataaactacgatttgctttgtaagtgtgaccgaattgccaagggggaggagcagtgccct
gaactgatcggcgagcctgtgaaaaggcgaaagtga
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