KEGG   Ursus arctos horribilis (North American brown bear): 113257718
Entry
113257718         CDS       T05909                                 
Symbol
IRAK4
Name
(RefSeq) interleukin-1 receptor-associated kinase 4 isoform X1
  KO
K04733  interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
Organism
uah  Ursus arctos horribilis (North American brown bear)
Pathway
uah04010  MAPK signaling pathway
uah04064  NF-kappa B signaling pathway
uah04620  Toll-like receptor signaling pathway
uah04621  NOD-like receptor signaling pathway
uah04722  Neurotrophin signaling pathway
uah04936  Alcoholic liver disease
uah05132  Salmonella infection
uah05133  Pertussis
uah05135  Yersinia infection
uah05140  Leishmaniasis
uah05142  Chagas disease
uah05145  Toxoplasmosis
uah05152  Tuberculosis
uah05161  Hepatitis B
uah05162  Measles
uah05164  Influenza A
uah05168  Herpes simplex virus 1 infection
uah05169  Epstein-Barr virus infection
uah05170  Human immunodeficiency virus 1 infection
uah05171  Coronavirus disease - COVID-19
uah05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:uah00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    113257718 (IRAK4)
   04064 NF-kappa B signaling pathway
    113257718 (IRAK4)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    113257718 (IRAK4)
   04621 NOD-like receptor signaling pathway
    113257718 (IRAK4)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    113257718 (IRAK4)
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    113257718 (IRAK4)
   05161 Hepatitis B
    113257718 (IRAK4)
   05171 Coronavirus disease - COVID-19
    113257718 (IRAK4)
   05164 Influenza A
    113257718 (IRAK4)
   05162 Measles
    113257718 (IRAK4)
   05168 Herpes simplex virus 1 infection
    113257718 (IRAK4)
   05169 Epstein-Barr virus infection
    113257718 (IRAK4)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    113257718 (IRAK4)
   05135 Yersinia infection
    113257718 (IRAK4)
   05133 Pertussis
    113257718 (IRAK4)
   05152 Tuberculosis
    113257718 (IRAK4)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    113257718 (IRAK4)
   05140 Leishmaniasis
    113257718 (IRAK4)
   05142 Chagas disease
    113257718 (IRAK4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    113257718 (IRAK4)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    113257718 (IRAK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:uah01001]
    113257718 (IRAK4)
Enzymes [BR:uah01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     113257718 (IRAK4)
Protein kinases [BR:uah01001]
 Serine/threonine kinases: TKL group
  IRAK family
   113257718 (IRAK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_fungal Death Haspin_kinase
Other DBs
NCBI-GeneID: 113257718
NCBI-ProteinID: XP_026357853
LinkDB
Position
Unknown
AA seq 460 aa
MNKPITSSTYVRCLNVGLIRKLSDFIDPQEGWKKLAVAIKKPSGDDRYNQFHIRRFEALL
QTGKSPTCELLFDWGTTNCTVGDLVHLLIQNEFFAPASLLLPDAVPKTVHTLPSKEAVTV
QQKHVPLHGKDRTFVLPVQNIEQNCMPPDSSSPENTSLEGSDTRFHSFSFYELKNVTNNF
DERPISLGGNKMGEGGFGVVYKGYVNNKTVAVKKLVAMVDISTEELKQQFDQEIKVMAKC
QHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDDTPPLSWHMRCKIAQGAANGIS
FLHENHHIHRDIKSANILLDEDFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEAL
RGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDTKMND
TDPTSIETMYSVASQCLHEKKNKRPDIKKVQQLLQDMTTS
NT seq 1383 nt   +upstreamnt  +downstreamnt
atgaacaaacccataacatcttcaacatatgtgcgctgcctcaatgttggactaattagg
aagctgtcagattttattgatcctcaagaaggatggaagaagttagcagtagctattaaa
aaaccatctggtgatgatagatacaatcagtttcacataaggagatttgaagcattactt
caaactggaaaaagtcccacttgtgaattgctgtttgactggggcaccacaaattgcaca
gttggtgatcttgtgcatcttttgattcaaaatgagttttttgccccagcaagtcttttg
ctaccagatgctgttcccaaaacggttcatacactaccttctaaagaagctgtaacagtt
cagcagaagcatgtgcctctccatggcaaagacaggacatttgtgttacctgtgcagaat
attgaacaaaactgtatgccacctgactcctcaagtccagaaaatacaagtttagaaggt
agtgatacacgttttcacagtttttcattttatgaactgaagaatgtcacaaataacttt
gatgagagacccatttctcttggtggcaacaagatgggagagggaggatttggagttgta
tataaaggctacgtgaacaacaaaactgtagcagtgaagaagcttgtagcaatggttgac
attagtactgaagaactgaaacagcagtttgatcaagaaataaaagttatggcaaagtgt
caacatgagaacttagtagaactgcttggtttctcaagtgatggagatgacctctgctta
gtgtatgtttatatgcccaatggctcattactagacaggctgtcttgcttggatgatact
ccaccactttcttggcacatgagatgcaagattgctcaaggtgcagctaatggcatcagt
tttttacatgaaaaccatcatattcatagagacattaaaagtgcaaatatcttactagat
gaagactttacagccaaaatatctgacttcgggcttgcacgggcttctgagaagtttgcc
cagacagtcatgactagcagaattgtgggaacaacagcttatatggcacctgaggcttta
cgaggagagataacacccaaatctgacatctacagctttggtgtggttttattagaaata
ataactggacttccagctgtggatgaacaccgtgagcctcagttattgctagatattaaa
gaagaaattgaagatgaagaaaagacaattgaagactatattgatacaaagatgaatgac
actgatcctacttccattgaaactatgtactctgttgctagtcaatgcttgcatgaaaag
aaaaataagagaccagatattaagaaggttcaacagctgctgcaagacatgacaacttct
taa

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