Ursus arctos horribilis (North American brown bear): 113263101
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Entry
113263101 CDS
T05909
Symbol
NFKB1
Name
(RefSeq) nuclear factor NF-kappa-B p105 subunit isoform X1
KO
K02580
nuclear factor NF-kappa-B p105 subunit
Organism
uah
Ursus arctos horribilis (North American brown bear)
Pathway
uah01523
Antifolate resistance
uah04010
MAPK signaling pathway
uah04014
Ras signaling pathway
uah04024
cAMP signaling pathway
uah04062
Chemokine signaling pathway
uah04064
NF-kappa B signaling pathway
uah04066
HIF-1 signaling pathway
uah04071
Sphingolipid signaling pathway
uah04151
PI3K-Akt signaling pathway
uah04210
Apoptosis
uah04211
Longevity regulating pathway
uah04218
Cellular senescence
uah04380
Osteoclast differentiation
uah04613
Neutrophil extracellular trap formation
uah04620
Toll-like receptor signaling pathway
uah04621
NOD-like receptor signaling pathway
uah04622
RIG-I-like receptor signaling pathway
uah04623
Cytosolic DNA-sensing pathway
uah04625
C-type lectin receptor signaling pathway
uah04657
IL-17 signaling pathway
uah04658
Th1 and Th2 cell differentiation
uah04659
Th17 cell differentiation
uah04660
T cell receptor signaling pathway
uah04662
B cell receptor signaling pathway
uah04668
TNF signaling pathway
uah04722
Neurotrophin signaling pathway
uah04917
Prolactin signaling pathway
uah04920
Adipocytokine signaling pathway
uah04926
Relaxin signaling pathway
uah04931
Insulin resistance
uah04932
Non-alcoholic fatty liver disease
uah04933
AGE-RAGE signaling pathway in diabetic complications
uah04936
Alcoholic liver disease
uah05010
Alzheimer disease
uah05022
Pathways of neurodegeneration - multiple diseases
uah05030
Cocaine addiction
uah05132
Salmonella infection
uah05133
Pertussis
uah05134
Legionellosis
uah05135
Yersinia infection
uah05140
Leishmaniasis
uah05142
Chagas disease
uah05145
Toxoplasmosis
uah05146
Amoebiasis
uah05152
Tuberculosis
uah05160
Hepatitis C
uah05161
Hepatitis B
uah05162
Measles
uah05163
Human cytomegalovirus infection
uah05164
Influenza A
uah05165
Human papillomavirus infection
uah05166
Human T-cell leukemia virus 1 infection
uah05167
Kaposi sarcoma-associated herpesvirus infection
uah05168
Herpes simplex virus 1 infection
uah05169
Epstein-Barr virus infection
uah05170
Human immunodeficiency virus 1 infection
uah05171
Coronavirus disease - COVID-19
uah05200
Pathways in cancer
uah05202
Transcriptional misregulation in cancer
uah05203
Viral carcinogenesis
uah05206
MicroRNAs in cancer
uah05207
Chemical carcinogenesis - receptor activation
uah05208
Chemical carcinogenesis - reactive oxygen species
uah05212
Pancreatic cancer
uah05215
Prostate cancer
uah05220
Chronic myeloid leukemia
uah05221
Acute myeloid leukemia
uah05222
Small cell lung cancer
uah05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
uah05321
Inflammatory bowel disease
uah05415
Diabetic cardiomyopathy
uah05417
Lipid and atherosclerosis
uah05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
113263101 (NFKB1)
04014 Ras signaling pathway
113263101 (NFKB1)
04064 NF-kappa B signaling pathway
113263101 (NFKB1)
04668 TNF signaling pathway
113263101 (NFKB1)
04066 HIF-1 signaling pathway
113263101 (NFKB1)
04071 Sphingolipid signaling pathway
113263101 (NFKB1)
04024 cAMP signaling pathway
113263101 (NFKB1)
04151 PI3K-Akt signaling pathway
113263101 (NFKB1)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
113263101 (NFKB1)
04218 Cellular senescence
113263101 (NFKB1)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
113263101 (NFKB1)
04620 Toll-like receptor signaling pathway
113263101 (NFKB1)
04621 NOD-like receptor signaling pathway
113263101 (NFKB1)
04622 RIG-I-like receptor signaling pathway
113263101 (NFKB1)
04623 Cytosolic DNA-sensing pathway
113263101 (NFKB1)
04625 C-type lectin receptor signaling pathway
113263101 (NFKB1)
04660 T cell receptor signaling pathway
113263101 (NFKB1)
04658 Th1 and Th2 cell differentiation
113263101 (NFKB1)
04659 Th17 cell differentiation
113263101 (NFKB1)
04657 IL-17 signaling pathway
113263101 (NFKB1)
04662 B cell receptor signaling pathway
113263101 (NFKB1)
04062 Chemokine signaling pathway
113263101 (NFKB1)
09152 Endocrine system
04920 Adipocytokine signaling pathway
113263101 (NFKB1)
04917 Prolactin signaling pathway
113263101 (NFKB1)
04926 Relaxin signaling pathway
113263101 (NFKB1)
09156 Nervous system
04722 Neurotrophin signaling pathway
113263101 (NFKB1)
09158 Development and regeneration
04380 Osteoclast differentiation
113263101 (NFKB1)
09149 Aging
04211 Longevity regulating pathway
113263101 (NFKB1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113263101 (NFKB1)
05202 Transcriptional misregulation in cancer
113263101 (NFKB1)
05206 MicroRNAs in cancer
113263101 (NFKB1)
05207 Chemical carcinogenesis - receptor activation
113263101 (NFKB1)
05208 Chemical carcinogenesis - reactive oxygen species
113263101 (NFKB1)
05203 Viral carcinogenesis
113263101 (NFKB1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
113263101 (NFKB1)
09162 Cancer: specific types
05212 Pancreatic cancer
113263101 (NFKB1)
05221 Acute myeloid leukemia
113263101 (NFKB1)
05220 Chronic myeloid leukemia
113263101 (NFKB1)
05215 Prostate cancer
113263101 (NFKB1)
05222 Small cell lung cancer
113263101 (NFKB1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
113263101 (NFKB1)
05170 Human immunodeficiency virus 1 infection
113263101 (NFKB1)
05161 Hepatitis B
113263101 (NFKB1)
05160 Hepatitis C
113263101 (NFKB1)
05171 Coronavirus disease - COVID-19
113263101 (NFKB1)
05164 Influenza A
113263101 (NFKB1)
05162 Measles
113263101 (NFKB1)
05168 Herpes simplex virus 1 infection
113263101 (NFKB1)
05163 Human cytomegalovirus infection
113263101 (NFKB1)
05167 Kaposi sarcoma-associated herpesvirus infection
113263101 (NFKB1)
05169 Epstein-Barr virus infection
113263101 (NFKB1)
05165 Human papillomavirus infection
113263101 (NFKB1)
09171 Infectious disease: bacterial
05132 Salmonella infection
113263101 (NFKB1)
05135 Yersinia infection
113263101 (NFKB1)
05133 Pertussis
113263101 (NFKB1)
05134 Legionellosis
113263101 (NFKB1)
05152 Tuberculosis
113263101 (NFKB1)
09174 Infectious disease: parasitic
05146 Amoebiasis
113263101 (NFKB1)
05145 Toxoplasmosis
113263101 (NFKB1)
05140 Leishmaniasis
113263101 (NFKB1)
05142 Chagas disease
113263101 (NFKB1)
09163 Immune disease
05321 Inflammatory bowel disease
113263101 (NFKB1)
09164 Neurodegenerative disease
05010 Alzheimer disease
113263101 (NFKB1)
05022 Pathways of neurodegeneration - multiple diseases
113263101 (NFKB1)
09165 Substance dependence
05030 Cocaine addiction
113263101 (NFKB1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
113263101 (NFKB1)
05418 Fluid shear stress and atherosclerosis
113263101 (NFKB1)
05415 Diabetic cardiomyopathy
113263101 (NFKB1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
113263101 (NFKB1)
04932 Non-alcoholic fatty liver disease
113263101 (NFKB1)
04931 Insulin resistance
113263101 (NFKB1)
04933 AGE-RAGE signaling pathway in diabetic complications
113263101 (NFKB1)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
113263101 (NFKB1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
uah03000
]
113263101 (NFKB1)
Transcription factors [BR:
uah03000
]
Eukaryotic type
beta-Scaffold factors with minor groove contacts
RHR (Rel homology region) Rel/Ankyrin
113263101 (NFKB1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RHD_DNA_bind
RHD_dimer
Ank
Ank_2
Ank_4
Ank_3
Ank_5
Death
Motif
Other DBs
NCBI-GeneID:
113263101
NCBI-ProteinID:
XP_026365430
LinkDB
All DBs
Position
Unknown
AA seq
972 aa
AA seq
DB search
MAEDDTYLGGHEQMFHLDPLTHTIFNPELFQPEMALPTADGPYLQILEQPKQRGFRFRYV
CEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNTHLHAHSLVGKHCED
GICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACTKGYNPGLLVHPDLAYLQA
EGGGDRQLTDREKEIIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIY
DSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGIWEGFGDF
SPTDVHRQFAIVFKTPKYKDVNITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQ
RKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGAGGTGPGYGFPHYGFPTYGGITFH
PGTTKSNAGMKHGTINTLSKNDSEGCGKSVDREAVNLSGKVTEPTERDKESSSGDDEITL
TYTVGVKEENSRFHDNLFLQKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQDENG
DSVLHLAIIHLHAQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEAVVDDLLR
AGADLSLLDRAGNSVLHLAAKEGQDKILSILLKHKKAAPLMDHPNGEGLNAIHLAVMSDS
MPCLLLLVAAGADVNAQERKSGRTALHLAVERDNISLAGCLLLEGDAHVDSTTYDGTTAL
HIAAGRGSTRLAALLKAAGADPLVENFEPLYELDDSWDKDGEDEGVVPGTTPLDMATNWQ
VFDILNGKPYEPEFTSDDLLAQGDMKQLTEEAKLQLYKLLEIPDPDKNWATLAQKLGLGI
LNNAFRLSPAPSKTLMDNYEVSGGTIRELVEALRQMGYTEAIEVIQAAFCTPGSVAPGPG
KAIPQTLSLPLSPASTRSPLDEVRDDSICDSGVETSFRKLSFTESLTSGSSLLTLNKVPH
EYGQEGPIEGKI
NT seq
2919 nt
NT seq
+upstream
nt +downstream
nt
atggcagaagacgatacgtatttgggagggcatgaacaaatgtttcatttggatcctttg
actcatacaatatttaatccagaattatttcaaccagaaatggcactacctacagcagat
ggtccataccttcaaatattagagcaacctaaacagagaggatttcgtttccgttatgta
tgtgaaggcccgtcccatggtggactccccggtgcatctagtgaaaagaacaagaagtcc
taccctcaggtcaaaatctgcaactatgtgggacctgcaaaggtcattgtccagttggtc
acaaatgggaaaaacacccacctgcatgcacacagcctggtgggaaaacactgtgaggac
gggatctgcactgtaactgccggacccaaggacatggtggtcggctttgcaaacttgggt
atacttcatgtgacaaagaaaaaagtatttgaaacactggaagcacggatgacagaggca
tgtacgaagggctacaatcccggacttttggtgcaccctgatctggcttacttgcaagcg
gaaggcggaggagaccggcagctcacagatcgggaaaaggagatcatccgccaggcagct
cttcagcagacgaaggagatggacctcagcgtggtgcggctcatgtttacagcttttctt
ccagacagcaccggcagcttcacgaggcgcctggagcccgtggtgtcagacgccatctac
gacagcaaagcccccaatgcgtccaacttgaaaattgtaagaatggacaggacagctgga
tgcgtaaccggaggggaagagatttatcttctctgtgacaaggttcagaaagatgacatc
cagattcgattttacgaagaggaggaaaatggtgggatctgggaaggatttggagatttt
tcccccacagatgttcatagacaattcgccatcgtcttcaaaactccaaagtataaagat
gtcaacatcacaaaaccagcttccgtgtttgtccagcttcggaggaaatctgatctggaa
accagcgaacccaaaccttttctctactaccctgaaatcaaagataaagaggaagtgcag
aggaaacggcagaagctcatgcctaatttctcagatagtttcggcggcgggagcggagct
ggagctggaggcggaggcatgtttggcagtggcggtggaggagggggtgctggaggtacg
gggccagggtatggcttccctcactacggatttcctacatatggtggaattactttccat
cctggaaccactaaatctaatgccgggatgaaacatggaaccataaacaccctatctaaa
aatgattctgaaggttgtggcaagagtgtggacagagaggcagtgaacctctctgggaaa
gtaactgaacccacagaacgagataaggagtccagctctggggatgatgagattactctg
acgtacacagtgggagtaaaggaagagaattctaggtttcacgataacctctttctccag
aaggctatgcagcttgccaagcggcatgccaacgccctttttgactacgcggtgacaggg
gatgtgaagatgctgctggctgtccaacgccacctcactgcagtgcaggatgagaatggg
gacagtgtcttacacttagcaatcatccatcttcatgcccagcttgtgagggatctactg
gaagtcacgtctggtttgatttctgatgacatcatcaatatgagaaatgatctctaccag
acgcccttgcacctggcggtgatcaccaagcaggaagctgtggtggacgacttgctgagg
gccggggccgacctgagccttctggaccgcgcgggtaactctgtgctgcacctagccgcc
aaagaaggacaagataagatcctcagtattttactcaagcacaaaaaggcagcgccactg
atggaccaccccaatggggaaggtctaaacgccattcacctagctgtgatgagcgacagc
atgccgtgtctgctgctgctggtggccgcgggcgccgacgtcaacgcccaggagcggaag
tccgggcgcacggcgctgcacctggcagtggagcgtgacaacatctccctggctggctgc
ctgctcctggagggtgatgcccatgtagacagtacgacctatgatggaactacagccctg
cacatagcagccgggagagggtccaccaggctggcggctcttctcaaggcagcaggcgca
gatcccctggtggagaactttgagcctctctatgagctggatgactcttgggacaaagat
ggagaggatgaaggagtcgtgcctggaaccacacctctagatatggccaccaactggcag
gtatttgatatattaaatgggaagccatacgagccagagtttacatctgatgatttattg
gcgcaaggagacatgaaacagctgactgaggaggcaaagctgcagctctacaagttgcta
gaaatccctgatccagacaaaaactgggctactctggcacagaaattaggtctggggata
ctaaataatgccttccggctgagtcctgctccttctaaaactcttatggacaactacgag
gtctccgggggcacgataagagagctggtggaggccctaagacaaatgggctataccgaa
gccatcgaagtgatccaggcggccttctgcaccccgggatctgtggcccccggccccggg
aaggccatacctcagaccctctcgctgcccctctcacctgcctccacgaggtcaccacta
gacgaggtccgagacgacagcatctgcgacagcggcgtggagacgtccttccgcaaactc
agctttacagagtctctgaccagtggcagctccttgctgactcttaacaaagtgccccac
gagtacgggcaggaaggacccatagagggcaaaatctag
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