KEGG   Ursus americanus (American black bear): 123780774
Entry
123780774         CDS       T07931                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor I isoform X1
  KO
K05459  insulin-like growth factor 1
Organism
uar  Ursus americanus (American black bear)
Pathway
uar01521  EGFR tyrosine kinase inhibitor resistance
uar01522  Endocrine resistance
uar04010  MAPK signaling pathway
uar04014  Ras signaling pathway
uar04015  Rap1 signaling pathway
uar04066  HIF-1 signaling pathway
uar04068  FoxO signaling pathway
uar04114  Oocyte meiosis
uar04115  p53 signaling pathway
uar04150  mTOR signaling pathway
uar04151  PI3K-Akt signaling pathway
uar04152  AMPK signaling pathway
uar04211  Longevity regulating pathway
uar04213  Longevity regulating pathway - multiple species
uar04510  Focal adhesion
uar04550  Signaling pathways regulating pluripotency of stem cells
uar04730  Long-term depression
uar04750  Inflammatory mediator regulation of TRP channels
uar04913  Ovarian steroidogenesis
uar04914  Progesterone-mediated oocyte maturation
uar04935  Growth hormone synthesis, secretion and action
uar04960  Aldosterone-regulated sodium reabsorption
uar05200  Pathways in cancer
uar05202  Transcriptional misregulation in cancer
uar05205  Proteoglycans in cancer
uar05214  Glioma
uar05215  Prostate cancer
uar05218  Melanoma
uar05224  Breast cancer
uar05410  Hypertrophic cardiomyopathy
uar05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:uar00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123780774 (IGF1)
   04014 Ras signaling pathway
    123780774 (IGF1)
   04015 Rap1 signaling pathway
    123780774 (IGF1)
   04066 HIF-1 signaling pathway
    123780774 (IGF1)
   04068 FoxO signaling pathway
    123780774 (IGF1)
   04151 PI3K-Akt signaling pathway
    123780774 (IGF1)
   04152 AMPK signaling pathway
    123780774 (IGF1)
   04150 mTOR signaling pathway
    123780774 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    123780774 (IGF1)
   04115 p53 signaling pathway
    123780774 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    123780774 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    123780774 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    123780774 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    123780774 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    123780774 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    123780774 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    123780774 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    123780774 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    123780774 (IGF1)
   04213 Longevity regulating pathway - multiple species
    123780774 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123780774 (IGF1)
   05202 Transcriptional misregulation in cancer
    123780774 (IGF1)
   05205 Proteoglycans in cancer
    123780774 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    123780774 (IGF1)
   05218 Melanoma
    123780774 (IGF1)
   05215 Prostate cancer
    123780774 (IGF1)
   05224 Breast cancer
    123780774 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    123780774 (IGF1)
   05414 Dilated cardiomyopathy
    123780774 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    123780774 (IGF1)
   01522 Endocrine resistance
    123780774 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:uar04052]
    123780774 (IGF1)
Cytokines and neuropeptides [BR:uar04052]
 Cytokines
  Growth factors (RTK binding)
   123780774 (IGF1)
SSDB
Motif
Pfam: Insulin DUF2865
Other DBs
NCBI-GeneID: 123780774
NCBI-ProteinID: XP_045635849
LinkDB
Position
Unknown
AA seq 187 aa
MGKISSLPTQLFKCCFCDFLKVKMHIMSSSHLFYLALCLLTFTSSATAGPETLCGAELVD
ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS
VRAQRHTDMPKAQKYRPPSTTKKTKSQRRRKGGPKKRPGGEQKVGTETSQQMKGKKKEQR
RETGARN
NT seq 564 nt   +upstreamnt  +downstreamnt
atgggaaaaatcagcagtcttccaactcaattatttaagtgctgcttttgtgatttcttg
aaggtaaagatgcacatcatgtcctcctcgcatctcttctacctggccctgtgcttgctc
accttcaccagctctgccacagctggaccggagacgctctgtggggctgaattggtggac
gctcttcagttcgtgtgtggagacaggggtttttatttcaacaagcccacggggtatggc
tccagcagtcggagggcacctcagacaggcatcgtggatgagtgctgcttccggagctgt
gatctgaggaggctagagatgtactgcgcacccctcaagcctgccaagtctgcccgttca
gtccgtgcccagcgccacactgacatgcccaaggctcagaagtatcgtcccccatctacc
accaagaaaacgaagtctcagaggagaaggaaaggtgggccaaagaaacgcccaggaggg
gaacagaaggtggggacggaaacaagtcagcagatgaaaggaaagaagaaagagcagaga
agggagactggagctagaaactga

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