Ursus americanus (American black bear): 123789299
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Entry
123789299 CDS
T07931
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar00010
Glycolysis / Gluconeogenesis
uar00020
Citrate cycle (TCA cycle)
uar00620
Pyruvate metabolism
uar00785
Lipoic acid metabolism
uar01100
Metabolic pathways
uar01200
Carbon metabolism
uar01210
2-Oxocarboxylic acid metabolism
uar04066
HIF-1 signaling pathway
uar04922
Glucagon signaling pathway
uar05230
Central carbon metabolism in cancer
uar05415
Diabetic cardiomyopathy
Module
uar_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
123789299 (PDHA2)
00020 Citrate cycle (TCA cycle)
123789299 (PDHA2)
00620 Pyruvate metabolism
123789299 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
123789299 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
123789299 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
123789299 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
123789299 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
123789299 (PDHA2)
Enzymes [BR:
uar01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
123789299 (PDHA2)
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Motif
Pfam:
E1_dh
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
123789299
NCBI-ProteinID:
XP_045649239
LinkDB
All DBs
Position
Unknown
AA seq
391 aa
AA seq
DB search
MKKMLAAAVSRVLSRVAQKPASRVLVASCNYSNDAMFEIKKCDLYRLEEGPPVTTVLTRE
DGLKYYRMMQTIRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPTDHVITSYR
AHGLCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYVKNFYGGNGIVGAQAPLGAGIAL
ACKYKGNNEVCLTLYGDGAANQGQIAEAFNMAALWKLPCVFICENNLYGMGTAAERAAAS
TDYYKRGHFIPGLRVDGMDVLCVREATKFAADYCRSEKGPIVMELQTYRYHGHSMSDPGI
SYRTRQEIQNVRSKSDPIMLLKDRMVNSKLATIEEFKEIDVEVRKEIEDAAHFAITDPEP
PLEELGHHIYCDNEPFEVRGSSQWIKFKSLS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaagaagatgctcgccgccgctgtctcccgcgtgttgtcccgggtcgcccagaagccc
gcgagcagagtgctggtggcttcctgtaactattcaaatgatgctatgttcgaaattaag
aaatgtgacctttatcgattagaagagggtccccctgtcacgacagtgctcacccgggag
gatgggctcaaatactacaggatgatgcagaccattcgccgaatggaattgaaggcagat
cagctgtataaacaaaaattcattcgcgggttctgtcacttgtgcgatggtcaggaagct
tgttgtgtgggtctggaggccgggatcaatcccaccgatcatgtcatcacatcctatcgg
gctcacggcttgtgctatactcgtggactttctgtccgatcgatccttgcggagctgacg
ggacgaaggggagggtgcgctaaaggcaaaggaggatctatgcatatgtatgtaaagaac
ttctatggcggcaacggcattgttggcgcccaggcacctctgggagccggcatcgccctg
gcctgtaaatataagggcaacaatgaggtctgtttgactctctatggggatggtgctgcg
aatcagggtcagatagcggaagctttcaatatggctgctttgtggaaattaccttgtgtt
ttcatctgtgagaataacctctatggcatgggcacggctgctgagagagcagcagcgagc
actgattactacaagagaggccattttatccctggactaagggtggatggaatggatgtt
ctatgtgttcgggaggcaactaagtttgccgctgactactgtagatctgaaaaggggccc
atagtgatggagctgcagacctaccgttatcatggacacagcatgagtgaccctggaata
agttatcgtacccgacaagaaattcagaatgtaagaagcaaaagtgatcccataatgctt
ctcaaagatagaatggtaaacagtaagcttgccactattgaagagttcaaggaaattgat
gtggaagtgaggaaagaaattgaggatgcagcccactttgctataactgaccctgaacca
cctttggaggaattaggtcatcacatctactgcgataatgaaccttttgaagttcgtggt
tcaagtcagtggatcaagtttaagtccctcagttaa
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