Ursus americanus (American black bear): 123795550
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Entry
123795550 CDS
T07931
Symbol
PTEN
Name
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
KO
K01110
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:
3.1.3.16
3.1.3.48
3.1.3.67
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar00562
Inositol phosphate metabolism
uar01100
Metabolic pathways
uar01521
EGFR tyrosine kinase inhibitor resistance
uar04068
FoxO signaling pathway
uar04070
Phosphatidylinositol signaling system
uar04071
Sphingolipid signaling pathway
uar04115
p53 signaling pathway
uar04140
Autophagy - animal
uar04150
mTOR signaling pathway
uar04151
PI3K-Akt signaling pathway
uar04218
Cellular senescence
uar04510
Focal adhesion
uar04931
Insulin resistance
uar05165
Human papillomavirus infection
uar05166
Human T-cell leukemia virus 1 infection
uar05200
Pathways in cancer
uar05206
MicroRNAs in cancer
uar05208
Chemical carcinogenesis - reactive oxygen species
uar05213
Endometrial cancer
uar05214
Glioma
uar05215
Prostate cancer
uar05218
Melanoma
uar05222
Small cell lung cancer
uar05224
Breast cancer
uar05225
Hepatocellular carcinoma
uar05230
Central carbon metabolism in cancer
uar05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
uar05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
123795550 (PTEN)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
123795550 (PTEN)
04070 Phosphatidylinositol signaling system
123795550 (PTEN)
04071 Sphingolipid signaling pathway
123795550 (PTEN)
04151 PI3K-Akt signaling pathway
123795550 (PTEN)
04150 mTOR signaling pathway
123795550 (PTEN)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
123795550 (PTEN)
09143 Cell growth and death
04115 p53 signaling pathway
123795550 (PTEN)
04218 Cellular senescence
123795550 (PTEN)
09144 Cellular community - eukaryotes
04510 Focal adhesion
123795550 (PTEN)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123795550 (PTEN)
05206 MicroRNAs in cancer
123795550 (PTEN)
05208 Chemical carcinogenesis - reactive oxygen species
123795550 (PTEN)
05230 Central carbon metabolism in cancer
123795550 (PTEN)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
123795550 (PTEN)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
123795550 (PTEN)
05214 Glioma
123795550 (PTEN)
05218 Melanoma
123795550 (PTEN)
05215 Prostate cancer
123795550 (PTEN)
05213 Endometrial cancer
123795550 (PTEN)
05224 Breast cancer
123795550 (PTEN)
05222 Small cell lung cancer
123795550 (PTEN)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
123795550 (PTEN)
05165 Human papillomavirus infection
123795550 (PTEN)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
123795550 (PTEN)
09167 Endocrine and metabolic disease
04931 Insulin resistance
123795550 (PTEN)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
123795550 (PTEN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
uar01009
]
123795550 (PTEN)
Enzymes [BR:
uar01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.16 protein-serine/threonine phosphatase
123795550 (PTEN)
3.1.3.48 protein-tyrosine-phosphatase
123795550 (PTEN)
3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
123795550 (PTEN)
Protein phosphatases and associated proteins [BR:
uar01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Dual specificity phosphatases)
Phosphatase and Tensin homologs (PTEN)
123795550 (PTEN)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PTEN_C2
DSPc
Y_phosphatase
PTPlike_phytase
Y_phosphatase3
DUF3256
Motif
Other DBs
NCBI-GeneID:
123795550
NCBI-ProteinID:
XP_045658333
LinkDB
All DBs
Position
Unknown
AA seq
369 aa
AA seq
DB search
MGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHN
PPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDF
YGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQ
FVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFW
VNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKAN
RYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDE
DQHTQITKV
NT seq
1110 nt
NT seq
+upstream
nt +downstream
nt
atggggtttcctgcagaaagacttgaaggcgtatacaggaacaatattgatgatgtagta
aggtttttggattcaaagcataaaaaccattacaagatatacaatctgtgtgctgaaaga
cattatgataccgccaaatttaactgcagagttgcacagtatccttttgaagaccataat
ccaccacagctagaacttatcaaacccttttgtgaagatcttgaccaatggctaagtgaa
gatgacaatcatgttgcagcaattcactgtaaagctggaaagggacgaactggtgtaatg
atttgtgcatatttattacatcggggcaaatttttaaaggcacaagaggccctagatttc
tatggggaagtaaggaccagagacaaaaagggagtaactattcccagtcagaggcgctat
gtgtattattatagctacctgttaaagaatcatctggattatagaccagtggcactgttg
tttcacaagatgatgtttgaaactattccaatgttcagtggcggaacttgcaatcctcag
tttgtggtctgccagctaaaggtgaagatctattcctccaattcaggacccacacgacgg
gaagacaagttcatgtacttcgagttccctcagccgttacctgtgtgtggtgacatcaaa
gtagagttcttccacaaacagaacaagatgctaaaaaaggacaaaatgtttcacttttgg
gtaaacacattcttcataccaggaccagaggaaacctcagaaaaagtagaaaatggaagt
ctatgtgatcaagaaattgatagtatttgcagtatagagcgtgcagataatgacaaggaa
tatctagtactcactttaacaaaaaatgatctcgacaaagcaaataaagacaaggccaac
cgatacttttctccaaattttaaggtgaagctgtacttcacgaaaacagtagaggagcca
tcaaatcccgaggctagcagttcaacttctgtaacaccagatgttagtgacaatgaacct
gaccattatcgatattctgacaccactgactctgatccagagaatgaaccttttgatgaa
gatcagcatacacagattacaaaagtctga
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integrated database retrieval system