Ursus maritimus (polar bear): 103668071
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Entry
103668071 CDS
T03271
Symbol
RET
Name
(RefSeq) proto-oncogene tyrosine-protein kinase receptor Ret
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr04010
MAPK signaling pathway
umr04020
Calcium signaling pathway
umr04151
PI3K-Akt signaling pathway
umr05200
Pathways in cancer
umr05216
Thyroid cancer
umr05223
Non-small cell lung cancer
umr05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103668071 (RET)
04020 Calcium signaling pathway
103668071 (RET)
04151 PI3K-Akt signaling pathway
103668071 (RET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103668071 (RET)
05230 Central carbon metabolism in cancer
103668071 (RET)
09162 Cancer: specific types
05216 Thyroid cancer
103668071 (RET)
05223 Non-small cell lung cancer
103668071 (RET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
umr01001
]
103668071 (RET)
Enzymes [BR:
umr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
103668071 (RET)
Protein kinases [BR:
umr01001
]
Receptor tyrosine kinases (RTK)
RET family
103668071 (RET)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD4
RET_CLD3
Pkinase
RIO1
Pkinase_fungal
Haspin_kinase
ABC1
Motif
Other DBs
NCBI-GeneID:
103668071
NCBI-ProteinID:
XP_008694567
UniProt:
A0A384CID3
LinkDB
All DBs
Position
Unknown
AA seq
861 aa
AA seq
DB search
MVPFPVTVYDEDDSAPTFLGGFDTASAVVEFKRKEGTVVATIRVFDADVVPASGELLRRY
TSTLLPGEAWALQTFRVEHSPNETLVQANGSFVRATVHDYRLVLNRSLPISESRSLQLAV
LVNDSDFQGPGEGVLLLHFNVTVLPVSLHLPSAYSFTVSKRARRFAQIGKVCVDNCQEFS
GIHVQYKLQLSSTNCSVLGVVTSAEDTTGTLFVNDTEALQRLDCSQLQYTVVAADRPTRR
QTQAPLVVTVEGTYVAEEPGCPLSCAVSKRRPECEECGGLGSLTGRCEWRQGDGKGITRN
FSTCSPSIKTCPDGHCDAVESRNVNICPQDCLRGGSIIGGHEPGDRWGIKAGFGICNCFP
EEKKCFCEPEDSQDPLCDELCRTVIAAAVLFSFIISMLLSTFCIHRYHKNAHKPPIASAE
MTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKIPEDPKWEFPRKNLVLGKTLGEG
EFGKVVKATAFRLKGKAGYTTVAVKMLKENASPSELRDLLSEFNLLKQVNHPHVIKLYGA
CSQDGPLFLIVEYAKYGSLRGFLRESRKAGPGYVGSGGSRSSSYLDNPEERALTMGDLIS
FAWQISRGMRYLAEMKLVHRDLAARNVLVAEGRKMKISDFGLSRDVYEEDSYVKRSKGRI
PVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGYRMERP
DNCSEEMYGLMLQCWKQEPDKRPVFADISKDLEKMMVKNRDYLDLAASTPSDSLLYDDGL
SEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPEESPVPLTRADGTNTVCPRYAND
RVYANWMVSPSAAQLTDAFDS
NT seq
2586 nt
NT seq
+upstream
nt +downstream
nt
atggtgcccttccctgtgaccgtgtacgatgaggacgactcggcgcccaccttcctcggg
ggcttcgacaccgccagcgctgtggtggagttcaagaggaaggagggcactgtggtggcc
acaatacgtgtcttcgacgcagatgtggtgccagcatctggggagctcctgaggagatac
acaagcacactactccctggggaggcctgggccctccagacattccgtgtcgagcactca
cccaacgagaccttggtccaggccaatggcagctttgtgcgggcaactgtgcacgactac
aggctggttctcaaccggagcctccccatctcggagagccgctccctgcagctggccgtg
ctggtcaatgactcggacttccagggccccggggagggtgtcctcctcctccacttcaac
gtgaccgtgctgcctgtcagcctgcacttacccagcgcctactccttcactgtgagcaag
cgggcccgccgctttgcccagattgggaaagtctgtgtggacaactgccaggagttcagc
ggcatccacgtgcagtacaagctgcagctctccagcaccaactgcagtgtcctgggggtg
gtcacctcagccgaggacaccacggggaccctgttcgtgaatgacacggaagccctgcag
cggctcgattgttctcaactccagtacacggtggtggctgccgaccggccaacccgcagg
cagacccaggccccgctggtcgtcaccgtggaggggacgtatgtggctgaggagccaggc
tgccctctgtcctgtgcagtcagcaagaggcggcctgagtgtgaggagtgcggcggcctg
ggctctctgacgggcaggtgcgagtggagacagggagatggcaaagggatcacgaggaac
ttctccacctgctcccccagcatcaagacctgccccgatggccactgtgatgctgtggag
agcagaaatgtcaacatctgcccccaggactgcctcaggggcggcagcatcattggtggg
cacgagccaggggaccgctggggaataaaagctggcttcggtatctgcaactgtttccct
gaagagaagaagtgcttctgtgagcctgaagacagccaggacccactgtgtgacgagctc
tgccgcacagtgatcgcggcggccgtgctcttctccttcatcatctccatgctgctctcc
accttctgcatccaccgctaccacaagaacgcccacaagccgcccatcgcctccgccgag
atgaccttccgccggccggcccaggccttcccagtcagttactcctcgtcgggtgcccgc
cggccctccctggactccatggagaaccaggtctctgtggatgccttcaagatcccggag
gatccaaagtgggaattccctcggaagaacttggttcttggaaaaactctgggagaaggt
gaatttggaaaagtggttaaggcaaccgccttccggcttaaaggcaaagcagggtacaca
accgtggccgtgaagatgctgaaagagaacgcctccccaagcgagctgcgggacctgctg
tcagagttcaacctcctgaagcaggtcaaccacccacatgtcatcaagctgtacggggcc
tgcagccaggatgggccactcttcctcattgtggagtacgccaagtacggctccctgcgg
ggattcctccgagagagccgcaaggccgggccgggctacgtgggcagtggaggcagccgc
agctccagctacctggacaaccccgaggagcgggccctgaccatgggtgacctcatctcc
ttcgcctggcagatctctcgggggatgcggtacctggcggagatgaagcttgtccatcgg
gacttggctgccagaaatgtcctggtagctgaggggcggaagatgaagatttcagatttt
ggcctatcccgagatgtttatgaagaggattcctatgtgaagaggagcaagggtcggatt
ccagtcaaatggatggcaattgagtctcttttcgatcatatctacaccacccagagtgat
gtgtggtccttcggtgtcctgctgtgggagattgtgactctgggaggcaacccctacccg
ggtattcctccagagcggctcttcaaccttctgaagacaggctaccggatggagaggcct
gacaactgcagcgaggagatgtatggtctaatgctgcagtgttggaagcaggaaccagac
aagaggccggtgtttgctgacatcagcaaagacctggagaagatgatggttaagaacaga
gactacttggacttggctgcgtccaccccatctgactccctgctttacgacgatggcctc
tcagaggaggagacgcccctggtggactgtaataatgctcccctccctcgagcccttccc
tccacgtggattgaaaacaaactctatggcatgtcagacccgaactggcctgaagagagt
cctgtaccactcacgagagctgatggcactaacactgtgtgtccacgatatgcaaatgat
agggtatatgctaactggatggtttcaccctcagcggcacaattaacggacgcgtttgat
agttaa
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