Ursus maritimus (polar bear): 103674684 Help Entry 103674684         CDS       T03271                                  Symbol GCK Name (RefSeq) hexokinase-4 isoform X1   KO K12407   glucokinase [EC:2.7.1.2] Organism umr  Ursus maritimus (polar bear) Pathway umr00010   Glycolysis / Gluconeogenesis umr00052   Galactose metabolism umr00500   Starch and sucrose metabolism umr00520   Amino sugar and nucleotide sugar metabolism umr00524   Neomycin, kanamycin and gentamicin biosynthesis umr01100   Metabolic pathways umr01200   Carbon metabolism umr01250   Biosynthesis of nucleotide sugars umr04910   Insulin signaling pathway umr04911   Insulin secretion umr04917   Prolactin signaling pathway umr04922   Glucagon signaling pathway umr04930   Type II diabetes mellitus umr04950   Maturity onset diabetes of the young umr05230   Central carbon metabolism in cancer Module umr_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate umr_M00549   Nucleotide sugar biosynthesis, glucose => UDP-glucose umr_M00892   UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc Brite KEGG Orthology (KO) [BR:umr00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     103674684 (GCK)    00052 Galactose metabolism     103674684 (GCK)    00500 Starch and sucrose metabolism     103674684 (GCK)    00520 Amino sugar and nucleotide sugar metabolism     103674684 (GCK)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     103674684 (GCK)  09150 Organismal Systems   09152 Endocrine system    04911 Insulin secretion     103674684 (GCK)    04910 Insulin signaling pathway     103674684 (GCK)    04922 Glucagon signaling pathway     103674684 (GCK)    04917 Prolactin signaling pathway     103674684 (GCK)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     103674684 (GCK)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     103674684 (GCK)    04950 Maturity onset diabetes of the young     103674684 (GCK) Enzymes [BR:umr01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.2  glucokinase      103674684 (GCK) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  103674684 NCBI-ProteinID:  XP_040500385 UniProt:  A0A8M1GXB8 LinkDB All DBs Position Unknown AA seq 465 aa AA seqDB search MLDDRARMEVTKKEKAEQILADFQLQEADLKKVMRRMQKEMARGLRLETHEEASVKMLPT YVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVTTKHQMYSIPEDAMTGTAE MLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNN IVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRRCEVGMIVGTGCNACYMEEMQN VELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRVVDENSLNPGQQLYEKLIGGKYMGE LVRLVLLKLVDENLLFRGEASEQLRTRGAFETRFVSQVESDSGDRKQIYNILSTLGLRPS ATDCDIVRRACESVSTRAAHMCAAGLAGVINRMRESRSEDAMRITVGVDGSVYKLHPSFK ERFHASVRRLTPSCEITFIESEEGSGRGAALISAVACKKACMLGQ NT seq 1398 nt NT seq  +upstreamnt  +downstreamnt atgctggatgacagagccaggatggaggtcaccaagaaggaaaaggcggagcagatcctg gcagacttccagctgcaggaggctgacctgaagaaggtgatgcggcggatgcagaaggag atggcgcggggcctgcggctggagacccacgaggaggccagcgtgaagatgctgcccacc tacgtacgctccaccccggagggctcagaagtcggggacttcctctccctggacctgggc ggcaccaacttcagggtgatgctggtgaaggtgggggagggcgaggaggggcagtggagt gtgacaaccaagcatcagatgtactccatccccgaggacgccatgactggcaccgctgag atgctcttcgactacatctccgagtgcatctccgacttcctggacaagcatcagatgaag cacaagaagctgcccttgggcttcaccttctccttccccgtgaggcatgaagacatagac aagggcatcctcctcaactggaccaagggcttcaaggcctcgggagcagaagggaacaac atcgtggggctcctccgtgacgccatcaaacggagaggggactttgaaatggacgtggta gcgatggtgaacgacacggtggccacgatgatctcctgctactacgaagaccgccggtgt gaggttggcatgattgtgggcacgggctgtaacgcctgctacatggaggaaatgcagaac gtggagctcgtggaaggggacgagggccgcatgtgcgtcaacactgagtggggtgccttt ggggactctggagagctggacgagttcctgctggagtatgaccgcgtggtggacgagaac tccctgaaccccggccagcagctgtacgagaagctcatcggcggcaagtacatgggcgag ctggtgcggctcgtgctgctaaaactcgtggacgaaaacctgcttttccgcggggaggcc tcggaacagctgcgcacgcgcggcgccttcgagacgcgcttcgtgtcgcaggtggagagt gactcgggcgaccgcaagcagatctacaacatcctgagcacgctggggctgaggccctcg gccaccgactgcgacatcgtgcgccgcgcctgcgagagcgtgtccacgcgcgccgcgcac atgtgcgccgccgggctggcgggcgtcatcaaccgcatgcgcgagagccgcagcgaggac gcgatgcgcatcaccgtgggcgtggacggctcggtgtacaagctgcaccccagcttcaag gagaggttccacgccagcgtgcgcaggctgacgcccagctgcgagatcacattcatcgag tcggaggagggcagtggccggggcgcggccctgatctccgcggtggcctgcaagaaggcc tgcatgctgggccagtga

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