Ursus maritimus (polar bear): 103677911
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Entry
103677911 CDS
T03271
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr00010
Glycolysis / Gluconeogenesis
umr00020
Citrate cycle (TCA cycle)
umr00620
Pyruvate metabolism
umr00785
Lipoic acid metabolism
umr01100
Metabolic pathways
umr01200
Carbon metabolism
umr01210
2-Oxocarboxylic acid metabolism
umr04066
HIF-1 signaling pathway
umr04922
Glucagon signaling pathway
umr05230
Central carbon metabolism in cancer
umr05415
Diabetic cardiomyopathy
Module
umr_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
103677911 (PDHA2)
00020 Citrate cycle (TCA cycle)
103677911 (PDHA2)
00620 Pyruvate metabolism
103677911 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
103677911 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
103677911 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
103677911 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
103677911 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
103677911 (PDHA2)
Enzymes [BR:
umr01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
103677911 (PDHA2)
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Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
103677911
NCBI-ProteinID:
XP_008705399
UniProt:
A0A384DF06
A0A452TDH6
LinkDB
All DBs
Position
Unknown
AA seq
391 aa
AA seq
DB search
MKKMLAAAVSRVLSRVAQKPASRVLVASCNYSNDAMFEIKKCDLYRLEEGPPVTTVLTRE
DGLKYYRMMQTIRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPTDHVITSYR
AHGLCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYVKNFYGGNGIVGAQAPLGAGIAL
ACKYKGNNEVCLTLYGDGAANQGQIAEAFNMAALWKLPCVFICENNLYGMGTAAERAAAS
TDYYKRGHFIPGLRVDGMDVLCVREATKFAADYCRSEKGPIVMELQTYRYHGHSMSDPGI
SYRTRQEIQNVRSKSDPIMLLKDRMVNSKLATIEEFKEIDVEVRKEIDDAAHFAITDPEP
PLEELGHHIYCDNEPFEVRGSSQWIKFKSLS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaagaagatgctcgccgccgccgtctcccgcgtgttgtcccgggttgcccagaagccc
gcgagcagagtgctggtggcttcctgtaactattcaaatgatgctatgttcgaaattaag
aaatgtgacctttatcgattagaagagggtccccctgtcacgacagtgctcacccgggag
gatgggctcaaatactacaggatgatgcagaccattcgccgaatggaattgaaggcagat
cagctgtataaacaaaaattcattcgcgggttctgtcacttgtgcgatggtcaggaagct
tgttgtgtgggtctggaggccgggatcaatcccaccgatcatgtcatcacatcctatcgg
gctcacggcttgtgctatactcgtggactttctgtccgatcgatccttgcggagctgacg
ggacgaaggggagggtgcgctaaaggcaaaggaggatctatgcatatgtatgtaaagaac
ttctatggcggcaacggcattgttggcgcccaggcacctctgggagccggcatcgccctg
gcctgtaaatataagggcaacaatgaggtctgtttgactctctatggggatggtgctgcg
aatcagggtcagatagcggaagctttcaatatggctgctttgtggaaattaccttgtgtt
ttcatctgtgagaataacctctatggcatgggcacggctgctgagagagcagcagcgagc
actgattactacaagagaggccattttatccctggactaagggtggatggaatggatgtt
ctatgtgttcgggaggcaactaagtttgccgctgactactgtagatctgaaaaggggccc
atagtgatggagctgcagacctaccgttatcatggacacagcatgagtgaccctggaata
agttatcgtacccgacaagaaattcagaatgtaagaagcaaaagtgatcccataatgctt
ctcaaagatagaatggtaaacagtaagcttgccactattgaagagttcaaggaaattgat
gtggaagtgaggaaagaaattgacgatgcagcccactttgctataactgaccctgaacca
cctttggaggaattaggtcatcacatctactgcgataatgaaccttttgaagttcgtggt
tcaagtcagtggatcaagtttaagtccctcagttaa
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