Variovorax sp. PMC12: C4F17_11240
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Entry
C4F17_11240 CDS
T05380
Name
(GenBank) bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase
KO
K01682
aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:
4.2.1.3
4.2.1.99
]
Organism
vam
Variovorax sp. PMC12
Pathway
vam00020
Citrate cycle (TCA cycle)
vam00630
Glyoxylate and dicarboxylate metabolism
vam00640
Propanoate metabolism
vam01100
Metabolic pathways
vam01110
Biosynthesis of secondary metabolites
vam01120
Microbial metabolism in diverse environments
vam01200
Carbon metabolism
vam01210
2-Oxocarboxylic acid metabolism
vam01230
Biosynthesis of amino acids
Module
vam_M00009
Citrate cycle (TCA cycle, Krebs cycle)
vam_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
vam_M00012
Glyoxylate cycle
Brite
KEGG Orthology (KO) [BR:
vam00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
C4F17_11240
00630 Glyoxylate and dicarboxylate metabolism
C4F17_11240
00640 Propanoate metabolism
C4F17_11240
Enzymes [BR:
vam01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.3 aconitate hydratase
C4F17_11240
4.2.1.99 2-methylisocitrate dehydratase
C4F17_11240
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Gene cluster
GFIT
Motif
Pfam:
Aconitase_2_N
Aconitase_B_N
Aconitase
Ketoacyl-synt_C
Motif
Other DBs
NCBI-ProteinID:
AVQ81478
UniProt:
A0A2P1V8L2
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Position
1:complement(2419416..2422001)
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AA seq
861 aa
AA seq
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MLQAYVDHVAERAALGIPPLPLSAKQTSEAIELLKSANAKDGAFLLDLLTYRVPAGVDDA
AKVKASYLAAVAHGTEKSEFISRARATELLGTMLGGYNISPMIDLLDDAEVGAVAAEGLK
KTLLMFDQFHDVKEKADKGNANAKGVLQSWADAEWFTSRPEVPESITVSIFKVAGEINTD
DLSPAPDATTRPDIPMHALAMHKNARPGIVPEEDGKRGPVKFIEDLRARGHLVAYAGDVV
GTGSSRKSATNSVLWFTGEDIPYVPNKRFGGVCLGGKIAPIFYNTMEDSGALPIELDVTQ
MNMGDVVELRPYEGKALKDGKVIAEFQVKSDVLFDEVRAGGRIPLIIGRGLTAKAREALG
LPVSTLFRLPQSPVDTKKGFSLAQKMVGRACGLPEGQGVRPGTYCEPKMTSVGSQDTTGP
MTRDELKDLACLGFSADLVMQSFCHTAAYPKKVDVKMHHELPEFMANRGGVSLRPGDGVI
HSWLNRLLTPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLVRFKGK
MQPGVTLRDLVNAIPLYAIKSGLLTVEKKGKKNIFSGRILEIEGLPDLKVEQAFELSDAS
AERSAAGCTVHLNKEPIIEYINSNITLMKWMIAEGYADARTLQRRIAAQEAWLANPQLLK
GDDDADYAAVIEIDLAEIHEPIVACPNDPDDVKTLSDVAGAAIDEVFIGSCMTNIGHFRA
ASKLLEGKRDIPVKLWIAPPTKMDAQQLTEEGHYGVFGNAGARTEMPGCSLCMGNQAQVR
EGATVMSTSTRNFPNRLGKNTNVYLGSAELAAICSRLGRIPTREEYMAASGVLDASSAQI
YQYLNFDKIEDYKGVADSVTA
NT seq
2586 nt
NT seq
+upstream
nt +downstream
nt
atgttgcaagcctacgttgaccatgtagccgaacgcgccgcgctcggtatcccgccgctg
cccctgagcgcgaagcagacctctgaagcgatcgagctcctcaagagcgcgaatgccaag
gacggtgccttcctgctggacctgctcacctatcgcgtgcccgccggcgtcgacgacgcg
gccaaggtcaaggcgagctacctcgcggccgtggcgcacggcaccgagaagagcgagttc
atttcgcgcgcccgcgcgaccgaactgctcggcaccatgctcggcggctacaacatcagc
cccatgatcgacctgctcgacgacgccgaagtgggcgccgtggcggcagagggcctgaag
aagaccctgctgatgttcgaccagttccacgacgtcaaggaaaaggccgacaagggcaac
gccaacgccaagggcgttctgcagagctgggccgacgccgagtggttcaccagccgcccc
gaagtgcccgagagcatcaccgtcagcatcttcaaggtggctggcgaaatcaacaccgac
gacctgtcgcccgcacccgatgcgacgacccgtcccgacatcccgatgcacgccctggcg
atgcacaagaacgcgcgccccggcatcgtgcccgaagaagacggcaagcgcggcccggtg
aagttcatcgaagacctgcgcgcgcgcggccacctcgtggcctacgccggcgacgtggtc
ggcacgggttcgtcgcgcaagagcgccaccaactcggtgctgtggttcaccggcgaagac
attccgtacgtgcccaacaagcgcttcggcggcgtctgcctcggcggcaagatcgctccc
atcttctacaacacgatggaagactcgggcgcgctgccgatcgaactcgacgtcacgcag
atgaacatgggcgacgtggtcgaactgcgcccctatgaaggcaaggcgctgaaggacggc
aaggtcatcgccgaattccaggtcaagagcgacgtgctgttcgacgaagtgcgcgccggc
ggccgcattccgctgatcatcggccgcggcctgacggccaaggcgcgtgaagcgctgggc
ctgcccgtttccacgctgttccgcctgccgcaaagcccggtcgacaccaagaagggcttc
tcgctcgcgcagaagatggtcggccgcgcctgcggcctgcccgaaggccagggcgtccgc
ccgggcacgtactgcgaacccaagatgacctcggtcggctcgcaggacaccaccggcccg
atgacgcgcgacgaactgaaggacctggcctgcctgggcttctcggccgacctcgtcatg
cagtcgttctgccacacggcggcgtaccccaagaaggtcgacgtcaagatgcaccacgaa
ctccccgagttcatggccaaccgcggcggcgtgtcgctgcgtccgggcgacggcgtgatc
cacagctggctcaaccgcctgctgacgcccgacaccgtgggcacgggcggcgacagccac
acccgcttccccatcggcatcagcttccccgcgggctccggcctcgtggccttcgcggcc
gccaccggcgtgatgccgctggacatgcccgaatcggtgctcgtgcgcttcaagggcaag
atgcagcccggcgtcacgctgcgcgacctggtcaacgcgattccgctgtatgccatcaag
tccggtctgctgacggtcgagaagaagggcaagaagaacatcttctcgggccgcatcctc
gagatcgaaggcctgcccgacctgaaggtggaacaggcattcgagctgagcgacgcctcg
gccgaacgctcggccgccggctgcacggtgcacctgaacaaggaaccgatcatcgagtac
atcaacagcaacatcacgctgatgaagtggatgattgccgaaggctacgccgatgcccgc
acgctgcagcgccgcatcgccgcgcaggaagcctggctcgcgaacccgcaactgctcaag
ggcgacgacgacgccgactacgccgccgtcatcgagatcgacctggccgagatccacgag
cccatcgtggcctgcccgaacgaccctgacgacgtgaagacgctgagcgacgtggccggt
gccgcgatcgacgaagtgttcatcggttcgtgcatgaccaacatcggccacttccgggcc
gcgtccaagctgctcgaaggcaagcgcgacatcccggtcaagctgtggatcgctccgccg
accaagatggacgcgcagcagctcaccgaagaaggccactacggcgtgttcggcaatgcc
ggtgcccgcaccgaaatgccgggctgctcgctgtgcatgggcaaccaggcacaggtgcgc
gaaggcgcgacggtcatgtcgaccagcacgcgcaacttcccgaaccgcctgggcaagaac
accaacgtgtacctcggctcggccgagctggccgccatctgctcgcgcctgggccgcatc
ccgacgcgcgaggaatacatggctgcttcgggcgtgctcgacgcctccagcgcgcagatc
taccagtacctgaacttcgacaagatcgaagactacaagggcgtggcggactcggtcacg
gcctga
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