Varroa destructor (honeybee mite): 111246654
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Entry
111246654 CDS
T07383
Name
(RefSeq) proto-oncogene tyrosine-protein kinase ROS-like
KO
K05088
proto-oncogene tyrosine-protein kinase ROS [EC:
2.7.10.1
]
Organism
vde
Varroa destructor (honeybee mite)
Brite
KEGG Orthology (KO) [BR:
vde00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
vde01001
]
111246654
Enzymes [BR:
vde01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
111246654
Protein kinases [BR:
vde01001
]
Receptor tyrosine kinases (RTK)
ROS family
111246654
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
fn3
Pkinase
Pur_ac_phosph_N
PhoD_N
Motif
Other DBs
NCBI-GeneID:
111246654
NCBI-ProteinID:
XP_022652321
LinkDB
All DBs
Position
Unknown
AA seq
3106 aa
AA seq
DB search
MRMKRSLGCRWRRLFTAVILMGLARCAIVYTELAESRIKDLCVHKCSQGYYRDELNTVCD
KECQSTCADGCRLWKLELSGNCSHLCEFRLAWSISESLEALYTIPQNVTTQEYGPPQGPP
QKVTCALSSYNQVAVSWRPPPFPAGPEVSYLLEARKTYGGTPFVHELITYNSTCDQTFSY
LFRELLPNTGYIVNVQAANRNGRGMSASCQVNTTDMEKESVNRGQGFAASGGDLYKFDLS
DTILGRGHVVFSVQGDGALIRGVTGSLQSRELYVSDNHGRIHVVGMDRSSSDRVPRTLSL
DVQKPSLLSYDWLNKRLFVFDESSWEIKSCTIEQRFICAVVVDGFSPSTAPKKLIVDSYN
GYLFWMAKGAEGEGSAMVLYRVDLIVAEENTKLHWDKAEVVHQSKGMKTFAVEYAQSRLH
VLDSSKDSIYAINMDSGNIVSKVRDQWAFYSNGSDIVFANEHFYVATTDGFFVEDGPTPQ
VGPSYRKFNNFTAFRFAFIDHKTAEPIPSPATPPENVRALFGSTFAKIFWDVPRPLTWQG
KGAFRKFLYTVDVTDLHTGKEVEHIENVKRSQLLITWLRNATKYRVTVRAHSELRATGPP
SSGFVGSTLKSDAETLVWSTLMSSTAGGLKRYVFASDATGDEAKMLVSSMQLQNNDVNAI
AWLDDTLFLGHNRTSLISVNLGNGLIRELPEVTGVTCLGIDSYARKVYWGSLTQRAIMRC
DMEGLRVELVTSNVVAHSLAVDSARGLIIWADQFGVYTANLSGKGYRALYETHISRGFVV
QGLVYDSKRGVAISSSRSIDGLELRMDSIDRNGARPVPVQMNDTSLRGPVIYLDDRLIWL
DRRSQPVITSLDGSFPAAMQYRPALGHGNGAFEDGSSDSELGHRDFPEALAVATKIRSSK
IMVIPKDIKDGEIKVEGTYDNFTIRWPQEQSLHVAVFYRIRVTPCSQNESDPCCSDNAQS
QWSVTSSKVKPLSLNTNRHVYPDKLRPHTRLAVQLQPYTDWANAKSVCHVLRSPESTPSA
PQTPKVFVAHRSVFPKYKAGVSYPEAEFRWSDPEHPNGFIKGYILNAWYRRNSPYLQTSQ
DTEPAAEVKLDNRIDQNNLQQAGEDSVIVWKNVRVSGHSYSIPKLVPNSTYFFKVSAFTS
IGEGPASTVLSINSDDEMPVPRLLVVDQQEAAPEADSPANRRGQNSLGKGIHHSSVQVSD
VDNGNVTVVSNKVTNPIGVAFLDDTVFWLEQRGPIMSSAMDGSNISVVHSTLETGTSLAV
DWVGRRLYWVEYDGTNSIIFVLDLADGRSVKIVLEIPKKYVSSIAADPFSSSLVFTVSSQ
PSMAASIMLVQLDGLNKRQLFSPRRRRSSLAHLYKNGTVAHGNTGDCTCLSVKPITRSVV
ALDAQSKKGPGTIYFADAEQGNIWRTDLVGCHCHLVANASLTKGLPPDVLTVDLQRVYWS
QRGREEVFSILKDSLGRPTHGKTENHVAAVKVASGVRNIRALNSQHYPDPMCMEISAPST
APAAVGAPKHSSLQVELFPPEIAKECSKISRPTVRYIVKYKKTKCLGTLCHREKQSLSAT
PVLQDLESYTNYTISYYYIDPYSQKLHGPSPPALFQTDDAEPGPAQFLSAVPLTPDSLEI
RWTATLPSRTRKPPRYELRYWEADSMAKREQKRPSDIKNFANHGMNLRAHNSNRIDGNET
LFSRNFEELADNNYTAIISDLKPSTIYKVEVVAVNVEKPEMRSAGTFVSSRTFDAPSDLT
ARNIGNRTIELTWSSSKKVKDRAGQESFRLEYSLEGRNWRPLAENRSSTLIKPDFEHSLK
VSGLTPYTDYWFRLRITYRSEYDRRLNFTWPFPSSVTNETASGFRVRTKEDVPELPGQPR
FTGPETNLTWEKSASNSGANVTYELQARQLDINTTQYWKELYIGDENHYDAYNLSSDSRY
LFRVRAINPNGSTDWVQTKKPLAIPAVMVIEKISSKSVIGIVLPSLLILILGVIMAVERF
SRRRSATHKQPHGLCPPVELITLRGLPYTSNFVQQHNELYTFCDVPLTDGELASIPTIDR
EQIRLNQLLGSGAFGDVYEGVLYGDTAQKIAVKMLRKGANELEKAEFLKEAKLMSNFRHP
HILTLLGISFDFNMSFIIMELMEDGDLLSVLRSCRNSSVGDPEESVGLTLEDLLSMCVDI
SKGCKYLEEMRFVHRDLAARNCLVASETLEDGRVKRVVKIGDFGLARDVYKSDYYRKEGE
GLLPVRWMAPEALLDGVFTNYTDVWAFGVLTWEVLSLGQQPYPAMSNVDVLNYVRAGGVL
ACLPGCPVELYALMCRCWSYTPEERPKFYHLLAELEKLQTRVQSLTLPAAGTLGGSSSAF
HNGTAPPTQYNYIIPPTTAAAEHYQQHQLEEHNQAHYNKGHRLGAETYRRLTSVPLLGLG
PNGRSKRIGVDNLAYEPSSTSSLPSSSCFCRPPSNSLPIASTNPCSLRLLSCQGPLETAL
ASWAATSSLQASMTSHGDPFYSLKPCSIAGWSQRYSKERSLNSMGQPTPGSLSDSLLNFE
VRTSTLNTTISTDSLRGCTGSLEIQSSSEAETEQLPLEPTLASNNDLAEIGRAVLPGELG
MQASYEKSDVLQSNVDFQVTDSNNKLTVLQWMLEDETEGSACSDLSAITAEDQQDDGVTL
RRDKPRPHSMELLGSVSSGSYDVTSSASTHQKMNAKTLTLQRASFANLPDDEIAGKMIGR
NLNELTADAQSDARLYLTLLPPSTSDGSAANVTTGTASEVSSKTQLQHLTERNLPPHANS
SSSETATNRTHDNNNHNRTGNKSDTMSSAVNNKINGANEKLTNKRINETRIAARSAEHQV
PPSRDHSMDHPVLIVGGATFNRSRPDKSATLGHMTGLNNHRSYYSQYPSLSCLVDVSSGS
GHIATGRRGCPTSQATTSNGVSQQKSAPQNYTGFTQTCPVAGLIMSSAATKNSSRVTNGA
GHGSALTSRWGATRTSAATQVTTPMSPTRTHLAVGTTVHNQAYNHVSHPAQHQQKQHQHY
NNNNKSNNNNPSRFVSYISVGSGEAKLSPSEVMPTSRSINSGKPDQIRCQLRQFLGAASQ
KMTPLTRTPAQLHKVNYEGIRPHTETISIHQGGDSNNNSYRTASWC
NT seq
9321 nt
NT seq
+upstream
nt +downstream
nt
atgcggatgaagagatccttgggctgtcggtggaggagactcttcaccgcggtgatcttg
atgggcctcgctcggtgcgctatcgtttataccgagttagcggaaagccggatcaaggat
ttatgtgtacacaaatgtagccagggctactatagggatgagctgaatactgtttgtgat
aaggagtgccaatcaacctgtgccgatggatgtcgcctatggaaactggaactgtccggc
aactgctcgcatttatgcgagtttcgacttgcttggtcaatatcggaaagcctcgaggca
ctgtacacgattccacaaaatgtgaccactcaggaatatggccccccacaaggtccccct
caaaaagtgacgtgcgcgcttagttcgtacaatcaggtagcagtctcatggcgtccaccc
ccatttcctgccggcccagaagtgtcctatctgcttgaggctagaaaaacctacgggggc
acgccgtttgtgcacgaactcatcacgtataattcaacctgtgaccagacattcagctat
ctattccgcgagctgcttccaaataccgggtatattgtcaatgtgcaagcagcaaatcgg
aacgggcgaggcatgtcagcctcatgccaggtgaacacgacggacatggaaaaagaaagc
gtaaatcgtgggcagggcttcgcggccagcggtggggacttgtataaatttgacctcagt
gacacgattctgggtcgcggtcatgtggtattcagcgtacaaggtgacggagccctcatt
agaggagtaactggaagccttcagtcaagggagctgtacgtgtccgataaccatggccgt
attcacgttgtcggaatggatcggagttcctcggatcgcgtacctcggacgctatcactt
gatgttcagaaaccatcacttctttcgtacgattggctaaataagcggttatttgttttt
gacgaatcgtcgtgggaaattaagtcgtgcacaatcgaacagagatttatatgcgccgtc
gtagtggacggattctcgccatcaacagccccgaaaaagctaatagtggattcatacaat
ggctacttgttttggatggccaaaggggctgaaggcgaaggctcggccatggttctgtac
cgtgtagatctcattgttgctgaagaaaacaccaagctccactgggacaaagctgaggtg
gtgcatcaatcaaagggaatgaaaacgttcgcagttgaatacgcccaatcccgacttcac
gttttggactctagcaaggacagcatatacgctatcaacatggattccgggaatattgta
tcgaaggtccgcgaccaatgggcattctacagcaacggctcggatatcgtatttgcgaac
gaacacttttatgtagccacgacggacggcttttttgttgaggacgggccgacacctcaa
gttggaccgtcctaccggaaattcaataactttactgcctttagatttgctttcattgac
cacaagactgctgaacccataccatctccagctacgccgccggaaaacgtgcgagcattg
ttcggttccacgtttgcaaaaattttctgggatgtgccaaggccactaacgtggcagggc
aaaggtgcctttcgtaaattcctctacacagtcgatgttactgatctgcacactggaaaa
gaggttgaacacatcgaaaacgttaaacgtagccagctattaattacttggttgcgtaat
gcaacgaagtacagagtgacagtgagagctcatagcgaactcagagcaactggcccgcca
tccagtggctttgtgggttccactcttaaaagcgatgcagaaacgctggtttggagcact
ctgatgtctagcacagctgggggtttgaagagatacgtttttgcctccgatgcaactggg
gacgaggcgaagatgttagtaagctcaatgcaactacaaaataatgatgtcaatgcaatt
gcatggctggatgataccttattcctgggacacaaccggaccagtttgattagtgtgaat
cttgggaatggattgattcgagagctgcctgaagttactggtgtaacgtgccttggtatt
gacagctatgccagaaaagtttactggggctctcttactcagcgtgcgataatgcgttgc
gacatggaaggcttgcgcgttgagctggtcacgtccaatgttgtagcacactcgttggcc
gtggatagcgctcgtggtctcataatttgggctgaccagttcggtgtctacaccgctaac
cttagcgggaaaggatacagggctctttacgagactcacatcagccgtgggtttgtcgtt
caaggtttggtgtatgactcaaagcgtggtgtagcgatatcaagtagtaggagcattgac
gggttagaactacgaatggacagcatcgacagaaacggcgcccgtccggtccccgtacaa
atgaacgacacttcattaagagggcctgtaatatacctggatgatcgtctcatttggctg
gatcgccgatctcagcccgtgatcacaagtcttgatggctcatttccagccgctatgcaa
tatcgtccggctttaggtcacggaaacggtgcctttgaggatggatccagcgacagcgaa
ttaggccaccgagatttccctgaagcgttggctgtggcgacaaaaatcagaagctccaaa
attatggtgataccaaaagatatcaaagatggagagataaaggtcgagggtacatacgac
aactttacgattcgctggccgcaggaacagtcgttacacgtcgctgttttctacaggatc
cgggtgactccgtgttcccaaaacgagagtgacccatgttgctcggataatgcacagtct
caatggtccgtaacctcctcgaaagtgaagccactaagcttgaataccaaccgacacgtt
taccctgataaacttcgtcctcacacccgtttagcggttcagcttcaaccatatactgat
tgggcaaatgcaaagtccgtctgccatgtactgcgttcgcctgagagtacaccctcagct
ccacagacgcccaaggtgtttgttgcccatcgttcggtgtttccgaaatacaaagctggc
gtatcttatcctgaagccgaattccgttggtctgatccagagcaccccaatggcttcata
aagggttacattctcaatgcgtggtatcgtcggaactcaccgtatttgcaaacgtcacag
gacacggagccggctgccgaagtaaaacttgacaatagaattgatcagaataatttacag
caagctggagaagacagcgtcatcgtttggaaaaatgtcagggtgtccgggcattcgtat
agtatacccaagctcgtaccaaacagcacatactttttcaaggtgagcgcattcacctcg
attggggaaggtcctgcgtcgacagttttatcaataaacagcgacgatgaaatgcctgta
cctcgattgttagtcgttgatcaacaggaagccgcccccgaagcagatagccctgctaac
cgcaggggtcaaaactcactgggcaaaggaatacaccatagttcagtgcaggtaagcgac
gtggacaacgggaacgtcacagtggtttcgaacaaagttactaatcctatcggggtggct
ttcctggatgacactgttttctggttagaacaacgcggtccgattatgtcttccgcaatg
gacggctccaacatctctgtggtccacagtacccttgaaactggaacatcacttgcggtc
gactgggtcggccgccgtctctattgggtcgaatatgacggaacaaactccattattttt
gtcctcgaccttgccgatggacgaagtgtgaagatcgttcttgagatacccaagaaatac
gtcagttcgatagccgctgacccattctcaagctcgttggtcttcacggtgtcgagccaa
ccatcgatggcagcttccattatgctagttcaattggacggtttgaataaacgacagctt
ttttctccgcgacggcgaaggtcatcactagcccatctttacaaaaacggaacagttgct
catggaaataccggagactgtacctgcttatcggttaagcctataactagatccgtggtc
gcgttagacgctcagtcaaagaaaggccctggtaccatttattttgcagatgcagaacaa
ggaaacatttggcgtaccgatctcgttggctgtcattgccacctggtagcgaatgctagt
ctgacgaaaggtcttccaccggacgtgttgacagtagatctacagagagtgtattggagt
caacggggccgcgaagaagtgtttagcatacttaaagactctctgggacgtcctacacat
ggcaagaccgagaaccatgtcgcagccgtaaaagtcgccagtggtgtcaggaacattcgt
gcccttaattctcagcattacccagacccaatgtgtatggaaataagcgcaccgtcaaca
gctccggcggcggttggagcaccgaagcatagttcgctccaggtagaacttttccctccg
gaaatagccaaggagtgctctaaaatctctcggccaacggtgcgctatattgtcaaatac
aagaaaactaaatgtttgggaacgctgtgtcatcgagaaaagcaatctctgtcagcaact
ccggttctacaagatctagagtcctacacaaactacacaatatcgtattactatattgat
ccatactcgcaaaaactgcatggaccatcacctcctgcgttgtttcaaaccgacgatgca
gagcctgggcccgcacaatttctgtctgccgtaccattaactcctgattctttggagatt
cgctggaccgccacattaccgagtcgtacaagaaagccaccacgatatgaattgcgttac
tgggaggctgattctatggcaaaacgcgaacagaagcgtccgtcagatattaaaaacttc
gccaaccatgggatgaacctgcgagctcataactccaatagaattgatggtaatgagacg
cttttctccaggaacttcgaggagttagctgacaacaactataccgcaataatctccgat
cttaaaccaagcaccatttacaaggtggaggttgtagctgtgaatgtggaaaagccggaa
atgaggagtgcgggcaccttcgtttccagccgaacttttgatgcaccgtcagatctcacc
gctcgaaatatcggaaatcgaacaatcgaacttacatggtcatcgtcgaaaaaagtaaag
gacagggccggacaggagagcttcaggctcgaatactcccttgaaggacggaattggcgg
ccgcttgcagagaatcgatcgagtaccttgattaagcccgatttcgagcattcgcttaaa
gttagtggactgacaccatacacagattactggtttcgtttacgtataacttatcgatca
gagtatgatcggcgtttgaacttcacttggccatttcctagctccgttacgaatgaaact
gcctcaggttttagagtgcgtacgaaagaggacgttcccgagttaccaggacaaccaagg
tttacaggacctgaaactaatctcacctgggaaaagagcgcctctaatagcggtgcaaat
gtcacttacgaactgcaggcaaggcaattggatataaacacaacgcagtactggaaagaa
ctttacatcggagatgagaatcactacgatgcgtacaatctgtcttccgatagtcgttac
ctttttcgagtgcgagctataaacccaaacggtagtactgactgggtgcaaacgaagaag
ccacttgcaattcctgccgtaatggttattgaaaaaattagttcaaaatcggtcataggc
attgtgctgcctagtttactaatcttaatactcggagttattatggccgtggaacgtttt
agtcgtcgtcggtcagccacgcacaaacagccacacgggctgtgtccaccggtagaactg
atcactctgcgggggctaccctatacgtctaactttgtacagcagcataatgaactctac
acattttgtgatgtgccgctaaccgatggggaactcgcttcgattccgacaattgaccga
gagcagatccgactaaaccagctgctgggttctggtgctttcggagatgtgtacgagggc
gtcctctatggcgatacggcacagaagatcgccgtcaaaatgctccgcaaaggcgccaac
gagctcgaaaaggcggaatttcttaaagaggccaagcttatgtccaacttccgtcatccg
cacatcctgacactgcttggcatctcgttcgacttcaatatgagtttcattattatggag
ctcatggaagatggggacctcctgtccgttctcagaagctgccgcaactcatcggttggc
gacccagaggaatcagttggactaaccctggaggatttattaagtatgtgtgtggacatt
tctaaaggctgcaagtaccttgaagaaatgcgttttgtgcacagagatctcgcagcccga
aactgtctggtggccagtgaaacattggaggacggtcgagtaaagagggtagtgaaaata
ggagatttcggtctggccagggatgtgtataagagtgactactatcgaaaagaaggcgaa
ggtctactacctgtgaggtggatggctcccgaagcccttctcgacggtgtcttcactaat
tatactgatgtgtgggcctttggagtgctcacatgggaagtcctctcactaggacaacag
ccgtacccagccatgagcaatgtcgacgtcctgaactatgttcgggctggcggagtctta
gcatgtttgcctggttgcccagtcgagttatatgcactaatgtgtcgctgttggagctac
acgcctgaagaacgacccaaattctaccatttgctagccgagttggagaaactgcaaaca
cgagtgcagtcactcacgctgccagcggctggtacgttgggaggcagttcaagtgccttc
cataatggaactgcccctccaactcagtacaactatataattcccccaacaacggcggca
gctgagcattatcaacaacatcaactcgaagaacataaccaggcacactacaacaaaggc
caccgactaggtgccgaaacgtatcggcggttgacatctgtaccgcttctgggtctcggc
ccaaacggtcgctccaaaagaataggcgtcgacaaccttgcgtatgaaccttcatcaacg
tcatctcttccctcgtcgtcatgcttctgccgtccgccaagcaattcgctcccgattgcc
tcgacgaatccgtgctctttacgattattaagctgtcaagggcctttggaaacagcattg
gcatcgtgggcagcaaccagctcgctccaagcatcaatgacttcccacggagacccattt
tattcattgaagccttgttcaatagcaggatggtcgcagagatactccaaagagcgatcg
ctgaactcgatgggtcagccgaccccaggaagtctcagtgattcattgctaaattttgag
gtgagaacatcaactctgaatacgacaatctcaacagattctcttcgcggctgcacgggg
tctttggaaattcaaagttcatccgaagcggaaaccgagcagcttcccttggaacctaca
ctagctagcaataacgatctggccgagatcggtcgagctgtcctgccaggcgagctgggg
atgcaagcttcatacgaaaagtcggatgtattgcagagcaatgtcgatttccaagtaact
gatagcaataataaactaacggtacttcaatggatgttggaagacgagactgaaggatca
gcctgctccgatctcagtgcaataacagcagaggatcaacaagacgacggagtgaccctc
aggcgcgacaagcctcgtccccattctatggaactattgggctccgtatcttcgggttca
tatgatgttacttcaagcgcgtcaactcaccaaaagatgaacgccaagacgctgacactt
caacgagcgtcctttgcgaacttgcccgatgacgagatagcgggtaagatgattggccgt
aatctaaatgagctcacagctgatgcccaaagtgatgcaagactctatctcactcttttg
ccgccaagcacaagcgacggaagcgctgcgaacgttaccactggcaccgcgtcagaagta
tcttcgaaaactcaactacagcatctcacggaacgcaatctaccaccacacgccaactcg
tcttcgtctgagacggccactaacaggactcatgacaataataaccataatagaaccggc
aacaaaagcgatactatgagcagtgccgttaacaataaaatcaatggagctaacgaaaag
ttaacaaacaaacgtatcaacgaaactcggattgccgcacgctcagcagaacatcaggtt
ccgccctcacgcgatcattcgatggatcatcctgtcctcatcgtcggaggggccaccttc
aatcgatctcgacctgacaaatctgccactcttggccatatgacaggccttaacaatcat
cgctcttattacagtcaatatccgtctcttagctgcctcgttgatgtcagcagtggcagt
ggacatatcgcaacaggcaggcgcggctgtcccacttctcaagcaactacttccaacggc
gttagtcagcagaaatctgccccccagaattacaccggcttcacacagacctgtccagta
gcaggactcataatgtcatctgcggctacaaaaaattcgtctcgagttactaatggtgcc
ggccacggcagcgctttgacttcccgctggggggcaacgagaacatcagctgcgacccaa
gttacaactccaatgtcacccacccgcacgcatttggccgtcggcaccaccgttcacaat
caagcctataaccacgtttctcacccagctcaacaccagcagaagcaacatcaacattat
aataacaacaataagagcaataataataatccttcccgattcgtcagctacatttctgtt
ggtagtggcgaagctaaattgtccccttcggaagtaatgcccactagccgttccattaac
agtggcaaacccgatcaaattcgctgtcaactacgccaatttctaggcgctgccagtcaa
aaaatgactccgttaacgcgaacgccggctcaattgcacaaagtgaattatgaggggatt
cggccccatacggaaactatttccatccaccaggggggtgatagcaataacaattcttac
cgaacggcctcttggtgctaa
DBGET
integrated database retrieval system
