Varanus komodoensis (Komodo dragon): 123019075
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Entry
123019075 CDS
T07701
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
vko
Varanus komodoensis (Komodo dragon)
Pathway
vko00270
Cysteine and methionine metabolism
vko00480
Glutathione metabolism
vko01100
Metabolic pathways
vko01240
Biosynthesis of cofactors
vko04216
Ferroptosis
Module
vko_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
vko00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
123019075 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
123019075 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
123019075 (GCLC)
Enzymes [BR:
vko01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
123019075 (GCLC)
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Ortholog
Paralog
GFIT
Motif
Pfam:
GCS
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
123019075
NCBI-ProteinID:
XP_044277468
Ensembl:
ENSVKKG00000000796
LinkDB
All DBs
Position
Unknown
AA seq
637 aa
AA seq
DB search
MGLLSQGSPLSWEKTQRHAEHVRRHGILQFLHIYRAVGERHKDVLKWGDEVEYMLVAFDH
KNKRAQLSLTGEEVLHTLQEKGEMVNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
QDNMRKRRQEAASVLKKNEAVCTVTSFPRLGCPGFTIPEYDPTPVETGASKSLFFPDQAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPNDDGEAARAAKPDHVYMD
AMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAAAPFYRGYVTDIDCRWGV
ISASVDDRTREERGLEPLKNNHYRIHKSRYDSIDSYLSECGEKYNDIDLTIDKEIYEHLI
KEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAV
RQGMFYFRKDICKGGNAVVDGCGPAQNGTETDAEEYILMSIDTIINGKEGVFPGLIPILN
SYLENMEVDVDTRCSILNYLKLIKKRASGELMTAARWMREFVANHPEYKHDSVITEEMNY
SLMWKCNQIAQEQVECPELLGVGFNKVKYSGMKTGTF
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atgggcctcctgtcgcagggctccccgctgagctgggagaagacgcagcggcacgcggag
cacgtgcgcaggcacggcatcctccagttcttgcacatctaccgagcggtcggggagagg
cacaaggacgtgctgaagtggggggacgaggtggaatacatgttggtagcttttgaccat
aaaaacaagagagctcagctgtccttaactggcgaagaagttcttcacactttgcaagaa
aagggtgaaatggtaaacccaaaccatccaactctgtggagacctgaatatggaagttac
atgattgaagggactcctggacagccatatggaggaacaatgtctgaatttaacaccgta
caagacaacatgagaaaacgacgtcaagaagctgcttctgtactgaaaaaaaatgaagct
gtttgcactgtgacctcatttccaagattaggctgtccaggattcacaataccagaatat
gatccaacacctgttgaaacaggggcctccaaatctctcttttttccagatcaagccatc
aacaaacatcctagatttagtactttaacaagaaacattcgtcatagaagaggagaaaaa
gtagtgataaatgtaccaatatttaaggacaagaatactccatcaccatttatagaaaca
ttccctaatgatgatggtgaagcagcaagagcagccaagcctgaccatgtatatatggat
gccatggggtttggaatgggcaattgttgccttcaggtaacattccaggcttgcagtatt
tctgaagcacgatatctttatgatcaactagcaacaatctgtcccattgtgatggcttta
agtgcagcagctccattctacagaggttatgtgacagatattgattgccgctggggagta
atatctgcatccgtagatgacagaacaagagaggagaggggattagagcccttgaagaac
aaccattacagaatccataaatcccgatatgattccatagatagttatctctctgaatgt
ggtgaaaagtacaatgacattgatttgacaatagataaagaaatctacgagcatctaata
aaagaaggcattgaccatctcttggcacaacacattgctcacttatttattcgtgatcca
ttaactctgtttgaagagaaaatacatctggatgatgcaaatgaatctgaccattttgag
aatattcagtcaacaaactggcagacaatgaggtttaagccacccccaccaaattcagat
attggatggagagttgagttcagaccaatggaggtccaattaacagactttgaaaactca
gcatatgttgtgtttgttgtgctgctgactcgagtcattctctcttacaagttggatttt
ctgattcctttatccaaggtggatgagaacatgaaagtagctcagaagcgggatgccgtc
cggcagggcatgttttatttcagaaaagacatttgtaaaggtggcaacgctgtagtggat
ggatgtggtccagctcaaaatggtacagaaacagatgcagaagagtatattttaatgagc
atagatacaataatcaatggaaaggagggagtatttcctggattaattccaattttaaac
tcctaccttgaaaatatggaagtggatgtggatacaagatgcagtattctaaactacctg
aaactaataaaaaagagagcatcaggagaattaatgacagctgctcgttggatgcgagag
tttgttgcaaaccatccagaatataaacatgatagtgtgatcacagaagagatgaactac
agcctgatgtggaagtgcaaccagattgcacaagagcaagttgagtgcccggagttgctt
ggagtaggctttaacaaagtaaaatacagtggaatgaaaactggcactttttga
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