Varanus komodoensis (Komodo dragon): 123024016
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Entry
123024016 CDS
T07701
Symbol
ARAF
Name
(RefSeq) serine/threonine-protein kinase A-Raf
KO
K08845
A-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
vko
Varanus komodoensis (Komodo dragon)
Pathway
vko04010
MAPK signaling pathway
vko04012
ErbB signaling pathway
vko04068
FoxO signaling pathway
vko04270
Vascular smooth muscle contraction
vko04810
Regulation of actin cytoskeleton
vko04910
Insulin signaling pathway
vko04914
Progesterone-mediated oocyte maturation
Brite
KEGG Orthology (KO) [BR:
vko00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
123024016 (ARAF)
04012 ErbB signaling pathway
123024016 (ARAF)
04068 FoxO signaling pathway
123024016 (ARAF)
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
123024016 (ARAF)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
123024016 (ARAF)
04914 Progesterone-mediated oocyte maturation
123024016 (ARAF)
09153 Circulatory system
04270 Vascular smooth muscle contraction
123024016 (ARAF)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
vko01001
]
123024016 (ARAF)
Enzymes [BR:
vko01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
123024016 (ARAF)
Protein kinases [BR:
vko01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
123024016 (ARAF)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
ABC1
Pkinase_fungal
Kdo
TUG-UBL1
C1_2
Motif
Other DBs
NCBI-GeneID:
123024016
NCBI-ProteinID:
XP_044287190
Ensembl:
ENSVKKG00000008822
LinkDB
All DBs
Position
Unknown
AA seq
656 aa
AA seq
DB search
MRHSQNYSGSLTNGFSSSCPDPSPAGGGGGEGPPPSSNSLMTTLTSRKKKRAMAETRGTI
KVDLPNQQRTVVTVRPGTTIYSSLDKALKVRGLNQDCCVVYKKRRDGRKTITDWNTDLVS
LEGAELSVEVLEDVPLTMHNFVRKTFFSIAFCDFCLKFMFHGFRCQTCGYKFHEHCSSRV
PTVCVDLATTHKPVYSHELWQYPALWSDSVPATPAQLSHEPITPHVISPRKQSPPRSEAF
SFPSPLSDGQCLQRHRSTSTPNVHMVSTTSPVDGNILEIVSKGHIAEAAGGPEVPPRTPP
PPPVSSMAAVSSGRRSPHPKSPGESPRERKAPTEDKKKPKSLGYRDSSYYWEVSPNEVTM
QKRIGAGSFGTVFKGRWHGDVAIKILKVTNPTSEQVQAFKNEMQVLRKTRHVNILLFMGF
MTRPSFAIITQWCEGNSLYQHLHVQETPLEMVQRIDVARQTAQGMDYLHAKNIIHRDLKS
NNIFLHEGLTVKIGDFGLATVKTRWSGSQQVEQPSGSILWMAPEVIRMQDPNPYSFQSDV
YSYGVVLYELLSGTLPYSHINNRDQIIFMVGRGYLSPDLSKVASNCPKAMRRLMGDCLKF
KREERPLFPQILASIESLQHSLPKIERSASEPALHRVAHNEELTFFALPPALWLRS
NT seq
1971 nt
NT seq
+upstream
nt +downstream
nt
atgagacacagccagaactactctggctctcttacgaatggcttctcttcatcctgccca
gacccaagccctgcaggtgggggtgggggtgagggccccccaccttcctcgaatagcctg
atgacaaccctcacttcccgcaagaagaagagagccatggccgagactcggggtaccatc
aaggtggatcttcccaatcagcagcgcactgtggtgactgtccggccaggtacaacaatc
tacagctctttggacaaggccctgaaggtgcgcgggctcaaccaggactgctgcgttgtc
tacaagaaaaggagagatgggcgaaagaccatcacagactggaacactgacctggtcagc
ctggagggggccgagctctctgtggaagttctggaggatgttccgctgactatgcacaac
tttgtccggaagaccttcttcagcattgccttttgtgatttctgccttaagttcatgttc
catggtttccgctgccagacgtgcggctacaagttccacgagcactgcagcagccgcgtg
ccgacggtttgcgtggatctcgccactacgcataagcctgtttacagtcatgagttgtgg
cagtaccctgccttgtggtctgacagtgtccctgccactccagcccagctcagccacgaa
cccatcactccacatgtgatcagccctcgcaagcagtcgcccccccgctccgaagccttc
agcttccccagccctctcagcgatgggcagtgcctgcagcgccaccgctccacttccact
cccaacgtccacatggtcagcaccaccagccctgtggacggcaacatccttgagattgtg
agcaagggccacattgcagaggctgcaggtgggccagaggtacctcctcgcaccccacca
cctcctcctgtctccagcatggctgctgtttcttctggccgacgctccccacaccctaag
tcccctggcgagtccccaagggagcgcaaggctcctaccgaagacaagaagaaaccgaaa
tccttggggtaccgggactcgagttactactgggaggtgtcccccaatgaggtaaccatg
cagaagcgcattggggccgggtcctttggcaccgtcttcaagggtcgctggcacggagat
gtggccatcaagattctcaaggtcaccaaccccaccagcgagcaagtgcaggccttcaag
aatgagatgcaggtgctcaggaaaacacgccatgtgaacatcctgctcttcatgggcttc
atgacgcgtcccagcttcgcaattatcacccagtggtgcgaaggcaacagcctctaccag
cacctccatgtgcaggagacgccgctggagatggtgcagcggatcgatgtggcccggcag
acggcacagggcatggattaccttcacgcaaagaacattatccaccgggacctcaaatcc
aacaatatcttcctgcatgaaggcctgacggtgaaaattggcgactttggccttgccaca
gtgaagacgcgctggagcggctcacagcaggtggagcagcccagtggctccatactctgg
atggcccccgaagtgatccgaatgcaggaccccaacccctacagcttccagtctgatgtc
tactcttacggagttgttctctatgagctcctctctgggacccttccctacagtcacatc
aacaaccgggaccagattatattcatggttggaaggggctacctgtcccctgaccttagt
aaggtggccagcaattgccccaaagccatgcgcaggctgatgggagactgccttaaattc
aagcgcgaggagaggcccctcttccctcagattttagcttccattgagtcactccagcat
tctttgcccaagattgagcgcagcgcttcagagcctgcactccaccgggtggcccacaat
gaagaactgaccttcttcgctcttccacctgccctgtggctccgcagctaa
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