Vulpes lagopus (Arctic fox): 121482235
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Entry
121482235 CDS
T07435
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
vlg
Vulpes lagopus (Arctic fox)
Pathway
vlg00010
Glycolysis / Gluconeogenesis
vlg00020
Citrate cycle (TCA cycle)
vlg00620
Pyruvate metabolism
vlg00785
Lipoic acid metabolism
vlg01100
Metabolic pathways
vlg01200
Carbon metabolism
vlg01210
2-Oxocarboxylic acid metabolism
vlg04066
HIF-1 signaling pathway
vlg04922
Glucagon signaling pathway
vlg05230
Central carbon metabolism in cancer
vlg05415
Diabetic cardiomyopathy
Module
vlg_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
vlg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
121482235 (PDHA1)
00020 Citrate cycle (TCA cycle)
121482235 (PDHA1)
00620 Pyruvate metabolism
121482235 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
121482235 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
121482235 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
121482235 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
121482235 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
121482235 (PDHA1)
Enzymes [BR:
vlg01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
121482235 (PDHA1)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
121482235
NCBI-ProteinID:
XP_041595988
LinkDB
All DBs
Position
X:15340857..15357361
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AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGVSQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLRYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDVLCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgctgtctcccgcgtgttgtcgggcgtctcccagaagccggca
agcagagtgttggtggcctcccgtaattttgcaaatgatgctacatttgaaattaagaaa
tgcgatcttcaccggctagaagagggccctcctgtcaccacagtgctcaccagggaggat
gggctcaggtactataggatgatgcagacagttcgccgaatggagttaaaggcagatcag
ctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgt
tgtgtgggcctggaggctggcataaatcccacagaccatcttatcacagcctatcgggct
catggctttacctttactcgtggcctttctgtcagagaaattctcgcagagcttacagga
agaagaggaggttgtgctaaaggaaaaggtggatcgatgcatatgtatgccaagaacttc
tatgggggtaatggcattgttggagctcaggtgcccttgggagcaggaattgctttggcc
tgtaagtataatggaaaggatgaggtctgtttgactttatatggcgatggtgctgctaat
cagggtcagatatttgaagcttacaacatggcagctttgtggaaattgccgtgtatcttc
atctgtgagaataaccgctacggaatgggaacgtctgttgagagagcagcagccagcact
gattactacaagagaggcgacttcattcctgggctgcgggtagatggaatggatgtcttg
tgtgtccgggaggcaacaaggtttgcagccgcctactgtagatctggaaaggggcccata
ttgatggagctacagacttaccgttaccatggacacagcatgagcgaccctggtgtcagt
taccgtacacgagaggagattcaggaagtaagaagtaagagtgaccctatcatgcttctc
aaggatagaatggtgaacagcaacctggccagtgtcgaggaactaaaggaaattgatgtt
gaagtgaggaaggaaattgaggatgctgcccagtttgccactgctgatccggaaccgcct
ttggaagaactaggctatcacatttacagcagcgatccgccttttgaagttcggggtgca
aatcagtggatcaagtttaagtctatcagttaa
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