Vicugna pacos (alpaca): 102524937 Help Entry 102524937         CDS       T08098                                  Symbol ACACB Name (RefSeq) acetyl-CoA carboxylase 2   KO K01946   acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15] Organism vpc  Vicugna pacos (alpaca) Pathway vpc00061   Fatty acid biosynthesis vpc00620   Pyruvate metabolism vpc00640   Propanoate metabolism vpc01100   Metabolic pathways vpc04152   AMPK signaling pathway vpc04910   Insulin signaling pathway vpc04920   Adipocytokine signaling pathway vpc04922   Glucagon signaling pathway vpc04931   Insulin resistance vpc04936   Alcoholic liver disease Brite KEGG Orthology (KO) [BR:vpc00001]  09100 Metabolism   09101 Carbohydrate metabolism    00620 Pyruvate metabolism     102524937 (ACACB)    00640 Propanoate metabolism     102524937 (ACACB)   09103 Lipid metabolism    00061 Fatty acid biosynthesis     102524937 (ACACB)   09110 Biosynthesis of other secondary metabolites    00254 Aflatoxin biosynthesis     102524937 (ACACB)  09130 Environmental Information Processing   09132 Signal transduction    04152 AMPK signaling pathway     102524937 (ACACB)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102524937 (ACACB)    04922 Glucagon signaling pathway     102524937 (ACACB)    04920 Adipocytokine signaling pathway     102524937 (ACACB)  09160 Human Diseases   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     102524937 (ACACB)    04931 Insulin resistance     102524937 (ACACB) Enzymes [BR:vpc01000]  2. Transferases   2.1  Transferring one-carbon groups    2.1.3  Carboxy- and carbamoyltransferases     2.1.3.15  acetyl-CoA carboxytransferase      102524937 (ACACB)  6. Ligases   6.3  Forming carbon-nitrogen bonds    6.3.4  Other carbon-nitrogen ligases     6.3.4.14  biotin carboxylase      102524937 (ACACB)   6.4  Forming carbon-carbon bonds    6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)     6.4.1.2  acetyl-CoA carboxylase      102524937 (ACACB) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  ACC_central Carboxyl_trans CPSase_L_D2 ACCA_BT Biotin_carb_N Biotin_carb_C Biotin_lipoyl ATP-grasp Dala_Dala_lig_C Motif Other DBs NCBI-GeneID:  102524937 NCBI-ProteinID:  XP_031526044 UniProt:  A0A6J2ZX70 LinkDB All DBs Position 32 AA seq 2521 aa AA seqDB search MILLLFLSCLIFSCLTFSWLKIWGKMTDSKQVIKSKSKVRFTPNQEPLPSSDSSQEPRQA NDNSSSLPKTTDQIEPASSKGPKDVSWPRNSQPPPQQNPQGDPPFSDDTSPAHQANGTGT KAVEAPNTNDLSSPAKPQGQRVKTLSKEDKKQAHIRRQLMTNFILGSFDDNSSDEDSGTG LFRESSRRGSRPSLGTLSLEAALIAGETETPVSTIRSSMSGLHLVRRGREQKRLDLHRDF TVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPE DLKANAEYIKMADQYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPE LLHKHEIAFLGPPSEAMWAMGDKIASTIVAQTLKVPTLPWSGSGLTVEWAEDALLQGQRI SIPEDIYDQGCVRDVDEGLEAAEKIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQS EIPGSPVFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIAMPA VFEFMEQCAVLLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPA AQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFEAPSNPPLARGHVIAARITSENPDEGF KPSSGTVQELNFRSSKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALK ELSIRGDFRTTVEYLTNLLETESFQNNDIDTSWLDHLIAEKVQAEKPDIMLGVVCGALNV ADSMFRTCMTDFLHSLERGQVLPAASLRNIVDVELIYGGVKYILKVARQSPTMFVLIMNG CHIEIDAHRLNDGGLLLSYNGNSHTTYMKEEVNSYRITIGNKTCVFEKENDPTVLRAPSA GKLMQYMVEDGGHVEAGGSYAEIEVMKMIMTLTVQESGRVKYIKRPGAVLEAGCVVARLE LDDPSKVHSAEPFMGELPAQQTLPILGEKLNQVFHNVLENLTNVMNGYCLPEPIFSIKLK DWVQKLLMTLRDPSLPLLELQETMTSLSGRIPAPVEKAVRRVMAQYASNITSVLCQFPSQ QIATILDCHAATLQRKADREVFFMNTQSIVQLVQRYRSGTRGYMKAVVLDLLRKYLLVEH HFQQAHYDKCVINLREQLKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSDEL TSILNELTQLSKTEHCKVALRARQVLIASHLPSYELRYNQVESIFLSAIDLYGHQFCPEN LKKLILSETTIFDVLPTFFYHANKIVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVE FQFMLPSSHPNRMAAPISVTNPELLRHSTELFMDSGFSPLCQRMGAMVAFQRFEDFTRNF DEVISCFTNVPKDTPLFSKARTTLFSEDDSKSLREEPIHILNVAIQYADHLEDEQLVPIF RTFVQSKKNILVNCGLRRITFLIAQEVSPILNAPVSRIGYISPPYLRTPHSRIQPTTDGI SEALNLLKHQGVQESGAWIKQAPSPAPSSACACVSVWFLSPVGLQFAEDRIYRHLEPALA FQLELSRLRNFDVTAMPCANHKMHLYLGAARVKEGVEVTDHRFFIRVIIRHSDLITKEAS FEYLQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPSKIEEAVRSMVMR YGSRLWRLRVLQAEVKINIRQTTLDSAVPIRLFITNESGYYLDISLYKEVTDPRSGNIMF HSFGNKQGPQHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKMWGSPDK YPKDILTYTELVLDPQGQLAEMNRLPGGNEVGMVAFKMRFKTPEYPEGRNVILISNDITF RIGSFGPREDLLYLRASEMARAEGIPKIYLAANSGARIGLAEEIKHMFQVAWEDPADPHK GFKYLYLTPQDYTKISPLNSVHCKHIEEEGESRYVITDIIGKEEGLGVENLRGSAMIAGE TSLAYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGAMALNKVLGREVYTSN NQLGGVQIMHYNGVSHITVPDDFEGVCTILEWLSYMPKDNHSPVPIITPTDPIDREIEFQ PSRVPYDPRWLLAGRPHPTLKGSWQSGFFDQGSFKEIMAPWASTVVTGRARLGGIPVGVI AVETRTVEVAVPADPANPDSEAKVIQQAGQVWLPDSAYKTAQAIKDFSRENLPLMIFANW RGFSGGMKDMYDQVLKFGAYILDGLRQYKQPILVYIPPYAELRGGSWAVMDTTINPLCIE MYADKESRGNVLEPEGIVEIKYRKKDLIKTMRRIDPTCKKLVEQLGTSELSDEDRKELEG QLKAREDLLLPIYHEVAVQFADLHDRPGTLLEKGLIADILDWKTTRTFLYWRLRRLLLES QVKQEILQACSELSHVHVQSMLRRWFVETEGAVKAYLWDNNQMVVQWLEQHWQVEDGLHS TIRENIKYLKRDSALKTIRGLVQENPEVAMDSLMYISQHISPAERAQVVHLLSTMDSPAT S NT seq 7566 nt NT seq  +upstreamnt  +downstreamnt atgatcctacttctttttctatcttgtctgattttctcctgcctgacattctcctggtta aaaatctgggggaaaatgacggactccaagcaagtcatcaagagtaaatcgaaagtgagg ttcaccccaaatcaggagcctcttccatcctcagacagctcccaggagccacgacaggca aatgacaacagtagctctttgccaaagaccactgaccagattgagccagcctccagcaaa ggtcccaaagatgtctcttggccaagaaactctcagccacccccacagcagaatccccaa ggagacccccctttctccgatgacacctccccagcacaccaagccaatgggaccggtacc aaagctgtggaagccccgaataccaatgacttgtcctcaccagccaaaccccagggccag cgagtgaaaaccctttccaaagaagacaagaagcaggcgcacatcagaaggcagctgatg accaacttcatcctgggctcttttgatgacaactcctccgatgaggactctggcactggc ttgttccgagagtcttcccggaggggcagccggcccagcctggggaccctgtccctggag gctgctctgatcgcaggcgagactgagacccccgtctccactataaggtccagcatgtca gggctccacctggtaagaagaggccgggaacagaagaggctggacctgcacagagacttc actgtggcttccccagccgagttcgtcacgcgctttggaggggatcgggtcatcgagaag gtgctcatcgccaacaatggcattgccgctgtgaagtgcatgcgctccatccgcaggtgg gcctacgagatgttccgaaacgagcgggccatccggtttgtagtcatggtgacccccgag gacctcaaggccaacgcagagtatatcaagatggcagatcagtatgtccccgtcccagga gggcccaacaacaacaattacgccaacgtggagctgattgtggacattgccaagagaatc cccgtgcaggcggtgtgggctggctggggccacgcttctgaaaaccccaaacttccggag ctcctgcacaagcacgagattgctttcttaggccctcccagtgaggccatgtgggccatg ggagacaagatcgcctccaccatcgtggcccagacgctgaaggtcccaacgctcccctgg agcggaagtggtctgacggtggagtgggcggaggacgccctgctgcaagggcaaagaatt agcatccccgaggacatttacgaccagggttgcgtgagagacgtagacgagggcttggag gcagcagaaaaaattggttttcccttgatgatcaaagcttctgaaggaggtggagggaaa ggaatccgaaaggcggagagtgcagaggacttccccatccttttcagacaagtgcagagc gagatcccaggctccccggtctttctcatgaagctggcccagcacgcccgtcacctggag gtccagatcctcgccgaccagtacgggaacgccgtgtccctgtttggacgtgactgttcc atccagcggaggcatcagaagatcattgaggaggcgccggctaccatcgccatgccggcc gtgttcgagttcatggagcagtgcgccgtgctcctggccaagactgtgggctacgtgagc gcagggacggttgaatacctctacagccaggatggcagcttccacttcttggagctgaat ccccgcctgcaggtggaacatccctgcacggagatgatcgccgatgtcaacctgccggcc gcccagctacagatcgccatgggcgtgccgctgcaccggctgaaggatatccggcttctg tatggagagtccccatggggggtgacgcccatttcttttgaagctccttccaaccctccc cttgcccgaggccacgtcattgcagccagaatcaccagcgaaaacccagatgaggggttt aagccaagctccggaacagtccaggaactgaatttccgcagcagcaagaatgtgtggggt tatttcagcgttgccgccgcgggtggcttacacgaatttgccgattcccagtttgggcac tgcttctcctggggagagaaccgggaagaggccatctcgaacatggtggtggctttaaag gaactgtccatccggggtgacttcaggaccaccgtggaatatctcactaatctcctggag accgagagcttccagaacaatgacattgacaccagctggttggatcaccttattgccgag aaagtgcaggccgagaagccagatatcatgctcggggtggtgtgcggagccttgaacgtg gccgactcgatgttcagaacctgcatgactgatttcttacactcactggaaaggggccag gtcctccccgcagcctctctccggaacattgtggatgtggaattaatttacggaggcgtg aagtacattcttaaggtggcccggcagtctccgaccatgttcgtcctcatcatgaatggc tgtcacatcgagatcgatgcccaccggctgaacgacgggggtctgctgctgtcctacaac ggtaacagccacaccacctacatgaaggaagaggtcaacagttaccgcatcaccatcggc aacaagacatgtgtgtttgagaaggagaatgatcccacggtcctgcgagccccttcggcg gggaagctgatgcagtacatggtggaggatgggggccacgtcgaggctgggggcagctac gctgagatcgaggtgatgaagatgatcatgaccctgaccgtgcaggaaagtggccgggtg aagtatatcaagcgcccgggggctgtgctggaagcgggctgtgtggtggccaggctggag ctcgatgacccttctaaagtgcactcagctgagccattcatgggagagctccccgcccag caaacgctgcccatcctcggagagaaactgaaccaggttttccacaacgtcctggagaat ctgaccaatgtcatgaacggctactgcctgccggagcctatttttagcatcaagctgaag gactgggtacagaagctcctgatgaccctccgggacccgtcgctgccgctgctggagctg caggagaccatgaccagcttgtcaggccgcatccctgcccctgtggagaaggcggtccgc agggtgatggcccagtatgccagcaacatcacctcggtgctgtgccagttccctagccag cagatagccactatcctggactgccatgcggccaccctgcagcggaaggctgaccgcgaa gtcttcttcatgaacacccagagcatcgtgcagctggtccagagataccgcagcgggacc cgcggctatatgaaggcggtggtgttggatctcctgcgaaaatatttactggttgagcac catttccaacaagcccactacgacaagtgtgtgataaacctcagggagcagctaaagcca gacatgtcgcaggtgctggactgcatcttctcccacgcgcaggtggctaagaagaaccaa ctggtgatcatgttgatcgatgagctctgtggtccagacccctccctgtcggatgagctg acctccatcctcaacgagctcactcagctgagcaaaaccgagcactgcaaagtggccctc agagccagacaggtcctgattgcctcccacctcccctcctacgagctgaggtacaaccag gtggagtccattttcctgtctgccatcgacctgtacggccatcagttctgcccggaaaac ctcaagaaattaatactctcagaaacgaccatatttgacgtcctgccaactttcttctat catgctaacaaaatcgtttgcatggcatccttggaggtttatgtgcggaggggctacatc gcctatgagttaaacagcctgcagcaccggcagctcccagatggcacctgtgtggtggaa ttccagttcatgctgccctcctcccacccaaaccggatggccgcccccatcagcgtcacc aaccctgaactgctgagacacagcacggagctcttcatggacagtggcttctccccactg tgccagcggatgggagccatggtcgccttccagagattcgaggatttcaccagaaacttt gatgaggtcatctcctgcttcaccaatgtgcccaaggacacccccctcttcagcaaggcc cgcactaccctgttctccgaggacgacagcaagagtctccgagaagagccgatccacatc ctgaacgtggccatccagtacgcggaccacctggaggacgagcagctggtgccgattttc cggacatttgtgcagtccaagaaaaacatccttgtgaattgtggactccgaagaatcaca ttcctaatagcccaagaggtcagtccgattctcaacgcacctgtcagccgaattgggtac atcagccctccgtatctgcggactccacattcgcggattcagccaaccaccgacggaatc tccgaggcactaaacctgctaaaacaccagggggtgcaggagagtggggcatggatcaag caggcacccagcccagcacccagctccgcgtgtgcctgtgtgtccgtctggtttctctct ccggtcggcctgcagtttgcggaagaccgcatctaccgtcacttggagccggccctggcc ttccagctggagctcagccggttgcggaacttcgacgtgaccgccatgccctgcgccaac cacaagatgcacctctacctgggcgccgccagagtgaaggagggcgtggaggtgaccgac cacaggttcttcatccgcgtcatcatcaggcactccgacctgatcaccaaggaagcctcc ttcgagtacctgcagaacgagggggagcggctgctcctggaggccatggacgagctggag gtggcgttcaacaacaccagcgtgcgcaccgactgcaaccacatcttcctcaacttcgtg cccaccgtcatcatggacccctctaagatcgaagaggcggtgcgctccatggtgatgcgc tacggcagccgcttgtggaggctccgcgtgctccaggctgaagtcaaaatcaacatccgc cagaccactttggacagcgctgtgcccatccgcctgttcatcaccaacgagtccggctac tacctggacatcagcctctacaaagaagtgaccgaccccagatctggaaatatcatgttt cactcctttggcaacaaacaagggccccagcatgggatgctgatcaacactccctacgtc accaaggacctgcttcaggccaagcggttccaggcccagtccctggggaccacctacgtg tatgacttcccggagatgttcaggcaggctctttttaaaatgtggggctccccagacaag taccccaaagacatcctgacatacaccgaattggtgctggaccctcagggccagctggcg gagatgaaccgacttcctggaggaaacgaggtgggcatggtggccttcaaaatgaggttt aagacccccgagtacccggaagggcggaacgttatcctcatcagcaatgacatcaccttc cgaatcggatcctttggccccagagaagaccttctgtacctgcgggcgtccgagatggcc cgagcagagggcatccctaaaatctacctcgctgccaacagcggggcccgtatcggcctc gcagaggagatcaaacacatgttccaggtggcttgggaggacccggcagacccccacaag ggatttaaatacctgtacctgaccccgcaagattacacgaaaatcagccctctgaactcc gtccattgtaaacacatcgaggaagaaggagaatccaggtacgtcatcacggatatcatt gggaaggaggaaggtctgggcgtagagaatctgcgaggctcggccatgattgccggggag acctccctggcttatgaagagattgtcaccatcagcttggtgacctgccgggccattggg atcggggcctacctggtgcggctgggccagcgagtgatccaggtggagaactcccacatc atcctgaccggggcaatggctctcaacaaggtcctgggcagagaggtttacacatccaac aaccagctgggcggcgtacagatcatgcactacaatggcgtctcccacatcaccgtgcca gacgacttcgagggtgtctgtaccatcctggagtggctgtcctatatgccaaaggataat cacagcccagtccctatcatcacacccactgaccccattgacagagaaatagaattccaa ccgtcccgcgtgccctacgacccccggtggttgcttgcaggaaggcctcacccaactctg aaggggtcctggcagagtggattcttcgaccagggcagtttcaaggagatcatggcgccc tgggcctcaaccgtggtgacggggcgagcaaggctggggggtatccccgtcggggtgatt gccgtggagacacgaacagtggaggtggctgtgcccgcagaccccgccaacccggattcc gaggccaaggtgatccagcaggcaggccaggtgtggctcccagactcggcctacaagacg gcccaggccatcaaggatttcagccgggagaacttgcccctgatgatctttgccaactgg cgggggttctcgggtggcatgaaagacatgtacgaccaggtgctgaaatttggagcctac atcttggatggcctccggcagtacaaacagcccatcctggtctacatcccgccctacgcg gagctccggggaggctcttgggcagtcatggacaccactatcaatccactgtgcatagaa atgtacgcggacaaagagagcagggggaatgttctagagccggagggaatagtggagatc aagtaccggaagaaagatctgataaagaccatgagaaggattgacccaacttgcaagaag ctcgtggaacagctcggaacgtctgagctctcagacgaggaccgcaaggagctggagggc cagctgaaggcccgggaggacctgctgctgcccatctaccacgaggtggcggtgcagttc gccgacctccacgacaggccgggcactttgctggagaaggggctcattgctgacatcctg gattggaaaaccacacgcaccttcttgtactggcgcctgcgccggctgctgctggagagc caggtcaagcaggagatcctgcaggcctgcagtgagctcagccacgtgcacgtccagtcc atgctacgccgctggttcgtggagacggagggggccgtcaaggcctacctgtgggacaac aaccagatggtggtgcagtggctggagcagcactggcaggtggaggacgggctgcactcc accatccgcgagaacatcaagtatttgaagcgggattctgccctcaagaccatccgaggc ctggttcaagaaaaccccgaggtggccatggactccctgatgtacataagccagcacatc agcccagccgagcgggcacaggtcgttcacctcttgtccaccatggacagcccggccacc tcctga

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