Vicugna pacos (alpaca): 102530493
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Entry
102530493 CDS
T08098
Symbol
LCK
Name
(RefSeq) tyrosine-protein kinase Lck isoform X1
KO
K05856
lymphocyte cell-specific protein tyrosine kinase [EC:
2.7.10.2
]
Organism
vpc
Vicugna pacos (alpaca)
Pathway
vpc04064
NF-kappa B signaling pathway
vpc04380
Osteoclast differentiation
vpc04650
Natural killer cell mediated cytotoxicity
vpc04658
Th1 and Th2 cell differentiation
vpc04659
Th17 cell differentiation
vpc04660
T cell receptor signaling pathway
vpc05135
Yersinia infection
vpc05166
Human T-cell leukemia virus 1 infection
vpc05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
vpc05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
vpc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
102530493 (LCK)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
102530493 (LCK)
04660 T cell receptor signaling pathway
102530493 (LCK)
04658 Th1 and Th2 cell differentiation
102530493 (LCK)
04659 Th17 cell differentiation
102530493 (LCK)
09158 Development and regeneration
04380 Osteoclast differentiation
102530493 (LCK)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102530493 (LCK)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
102530493 (LCK)
09171 Infectious disease: bacterial
05135 Yersinia infection
102530493 (LCK)
09163 Immune disease
05340 Primary immunodeficiency
102530493 (LCK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
vpc01001
]
102530493 (LCK)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
vpc03036
]
102530493 (LCK)
Enzymes [BR:
vpc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
102530493 (LCK)
Protein kinases [BR:
vpc01001
]
Non-receptor tyrosine kinases
SRC family
102530493 (LCK)
Chromosome and associated proteins [BR:
vpc03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
102530493 (LCK)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_2
SH3_9
ABC1
Haspin_kinase
SH3_16
Kdo
SH3_3
Motif
Other DBs
NCBI-GeneID:
102530493
NCBI-ProteinID:
XP_006196992
UniProt:
A0A6I9HY71
LinkDB
All DBs
Position
13
AA seq
509 aa
AA seq
DB search
MGCSCSSNLEDDWMENIDVCENCHYPIVPLDVKATLPIRNGSEVRDPLVTYEGSNPPASP
LQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQNGEWWKAQSLTTGQEGFIPFNFVAKAN
SLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKH
YKIRNLDKGGFYISPRITFPGLHELVRHYTNSSDGLCTRLSRPCQTQKPQKPWWEDEWEV
PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL
VRLYAVVTQEPIYIITEYMENGSLVDFLKTPTGIKLTINKLLDMAAQIAEGMAFIEERNY
IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK
SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVQPDNCPEELYHLMMLCWKER
PEDRPTFDYLRSVLEDFFTATEGQYQPQP
NT seq
1530 nt
NT seq
+upstream
nt +downstream
nt
atgggctgtagctgcagctcaaaccttgaagatgattggatggaaaacattgatgtatgt
gagaactgccattacccaatagtcccactggatgtcaaggccacgctgcccatccggaat
ggctctgaagtgcgggatccactggtcacttatgaaggctccaaccctccagcctctcca
ctgcaagacaacctggttatcgccctgcacagctatgagccctctcacgatggagacctg
ggcttcgagaagggtgaacagctacgcatcctggagcagaacggcgagtggtggaaggcg
cagtccctgaccacaggccaggaaggtttcatccccttcaacttcgtggccaaagcaaac
agcctggagcccgaaccatggttcttcaaaaacctgagccgcaaggacgcggagagacag
ctcctggcgcccgggaacacgcacggttccttcctgatccgggagagcgagagcaccgcg
gggtcgttttcactgtctgtccgggacttcgaccagaaccagggagaagtggtgaaacat
tacaagatccgtaacctggacaaaggcggcttctacatctcccctcgcatcacttttcct
ggcttgcatgaactggtccgccattacacaaattcttcggacgggttgtgcacgcggttg
agccgcccctgccagacccagaagccccagaagccctggtgggaggacgagtgggaggtt
cccagggagacgctgaagctggtggagcggctgggggctggccagttcggggaggtgtgg
atggggtactacaacgggcacacgaaggtggcagtgaagagcctgaagcagggcagcatg
tcccccgatgccttcctggccgaggccaatctcatgaagcagctgcagcaccagcggctg
gttcggctctacgctgtggtcacccaggagcccatctacatcatcacggaatacatggag
aacggaagcctggtggattttctcaagacccccacaggcatcaagctgaccatcaacaaa
ctcttggacatggcagcccaaattgcagagggcatggcattcattgaagagcgaaattac
atccaccgtgacttgagggcagccaacatcctggtgtcagataccctgagctgcaagatc
gcagattttggcctagcacgtctgattgaggacaatgagtacacagccagagagggggcc
aagtttcccattaagtggacagcaccagaggccattaactacgggacattcaccatcaag
tcggacgtgtggtctttcgggatcctgctgacagagattgtcactcatggccgcatccct
tacccagggatgaccaatcctgaggtgattcagaacctggagcgaggctaccgcatggta
caacctgacaactgtccagaggagttgtaccacctcatgatgctgtgctggaaggagcgc
ccggaggatcggcccacctttgactacctgcgcagcgtgctggaggacttcttcacggcc
acagagggccagtaccagccccagccctga
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