Vicugna pacos (alpaca): 102534219 Help Entry 102534219         CDS       T08098                                  Symbol ADCY5 Name (RefSeq) adenylate cyclase type 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism vpc  Vicugna pacos (alpaca) Pathway vpc00230   Purine metabolism vpc01100   Metabolic pathways vpc01522   Endocrine resistance vpc04015   Rap1 signaling pathway vpc04022   cGMP-PKG signaling pathway vpc04024   cAMP signaling pathway vpc04062   Chemokine signaling pathway vpc04072   Phospholipase D signaling pathway vpc04114   Oocyte meiosis vpc04211   Longevity regulating pathway vpc04213   Longevity regulating pathway - multiple species vpc04261   Adrenergic signaling in cardiomyocytes vpc04270   Vascular smooth muscle contraction vpc04371   Apelin signaling pathway vpc04540   Gap junction vpc04611   Platelet activation vpc04713   Circadian entrainment vpc04714   Thermogenesis vpc04723   Retrograde endocannabinoid signaling vpc04724   Glutamatergic synapse vpc04725   Cholinergic synapse vpc04726   Serotonergic synapse vpc04727   GABAergic synapse vpc04728   Dopaminergic synapse vpc04750   Inflammatory mediator regulation of TRP channels vpc04911   Insulin secretion vpc04912   GnRH signaling pathway vpc04913   Ovarian steroidogenesis vpc04914   Progesterone-mediated oocyte maturation vpc04915   Estrogen signaling pathway vpc04916   Melanogenesis vpc04918   Thyroid hormone synthesis vpc04921   Oxytocin signaling pathway vpc04923   Regulation of lipolysis in adipocytes vpc04924   Renin secretion vpc04925   Aldosterone synthesis and secretion vpc04926   Relaxin signaling pathway vpc04927   Cortisol synthesis and secretion vpc04928   Parathyroid hormone synthesis, secretion and action vpc04934   Cushing syndrome vpc04935   Growth hormone synthesis, secretion and action vpc04970   Salivary secretion vpc04971   Gastric acid secretion vpc04972   Pancreatic secretion vpc04976   Bile secretion vpc05012   Parkinson disease vpc05030   Cocaine addiction vpc05031   Amphetamine addiction vpc05032   Morphine addiction vpc05034   Alcoholism vpc05163   Human cytomegalovirus infection vpc05166   Human T-cell leukemia virus 1 infection vpc05200   Pathways in cancer vpc05207   Chemical carcinogenesis - receptor activation vpc05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:vpc00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102534219 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102534219 (ADCY5)    04371 Apelin signaling pathway     102534219 (ADCY5)    04072 Phospholipase D signaling pathway     102534219 (ADCY5)    04024 cAMP signaling pathway     102534219 (ADCY5)    04022 cGMP-PKG signaling pathway     102534219 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102534219 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     102534219 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102534219 (ADCY5)    04062 Chemokine signaling pathway     102534219 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     102534219 (ADCY5)    04923 Regulation of lipolysis in adipocytes     102534219 (ADCY5)    04912 GnRH signaling pathway     102534219 (ADCY5)    04913 Ovarian steroidogenesis     102534219 (ADCY5)    04915 Estrogen signaling pathway     102534219 (ADCY5)    04914 Progesterone-mediated oocyte maturation     102534219 (ADCY5)    04921 Oxytocin signaling pathway     102534219 (ADCY5)    04926 Relaxin signaling pathway     102534219 (ADCY5)    04935 Growth hormone synthesis, secretion and action     102534219 (ADCY5)    04918 Thyroid hormone synthesis     102534219 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     102534219 (ADCY5)    04916 Melanogenesis     102534219 (ADCY5)    04924 Renin secretion     102534219 (ADCY5)    04925 Aldosterone synthesis and secretion     102534219 (ADCY5)    04927 Cortisol synthesis and secretion     102534219 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102534219 (ADCY5)    04270 Vascular smooth muscle contraction     102534219 (ADCY5)   09154 Digestive system    04970 Salivary secretion     102534219 (ADCY5)    04971 Gastric acid secretion     102534219 (ADCY5)    04972 Pancreatic secretion     102534219 (ADCY5)    04976 Bile secretion     102534219 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     102534219 (ADCY5)    04727 GABAergic synapse     102534219 (ADCY5)    04725 Cholinergic synapse     102534219 (ADCY5)    04728 Dopaminergic synapse     102534219 (ADCY5)    04726 Serotonergic synapse     102534219 (ADCY5)    04723 Retrograde endocannabinoid signaling     102534219 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102534219 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     102534219 (ADCY5)    04213 Longevity regulating pathway - multiple species     102534219 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     102534219 (ADCY5)    04714 Thermogenesis     102534219 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102534219 (ADCY5)    05207 Chemical carcinogenesis - receptor activation     102534219 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102534219 (ADCY5)    05163 Human cytomegalovirus infection     102534219 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     102534219 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     102534219 (ADCY5)    05031 Amphetamine addiction     102534219 (ADCY5)    05032 Morphine addiction     102534219 (ADCY5)    05034 Alcoholism     102534219 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102534219 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102534219 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102534219 (ADCY5) Enzymes [BR:vpc01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102534219 (ADCY5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  102534219 NCBI-ProteinID:  XP_015104581 UniProt:  A0A6J0AWP6 LinkDB All DBs Position 1 AA seq 1194 aa AA seqDB search MSSSKSVSPPGYAAQTTAAPASRGGPEHRSAWGEADSRANGYPHAPGGSARGSTKKPGGA VTPQKQQRLASRWRSDDDDDPPLSGDDPLVGGFGFSFRSKCLEERRGKGRAADELEAGAV EDDEESGDGGSSAGSGSAPGAVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLNQS SLTMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLVAAVSVILVMAVLCNRAAFHQDHMGL ACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSAL HLAIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLH SQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTS LASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEM GMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGK AGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMN RQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEFL GRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQI TIVPHSVFMLSFYLTCFLLLTLVVFVSVIYSCVKLFPAPLQTLSRKIVRSKMNSTLVGVF TITLVFLSAFVNMFTCNSKDLFGCLADEHNVSVSQVNACHVVESAVNYSLGDERGFCGSS WPNCNFPEYFTYSVLLCLLACSVFLQISCIGKLVLMLAIELVYVLVVEVPGVTLFDNADL LVTANAIDFSNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKL QATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANF SEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTY DKVGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWG NTVNVASRMDSTGVPDRIQVSAGTSTPPTWGPLCVAKWSSSSPHSCQSEFLQPI NT seq 3585 nt NT seq  +upstreamnt  +downstreamnt atgtccagctccaaaagcgtgagccccccgggctacgcggcgcagacaacggcggcgccg gcgtcccggggaggcccagaacaccgctccgcgtggggtgaggcggactcccgcgccaat ggctaccctcacgcgcctgggggttcggcccgcgggtctaccaagaaacccgggggagcg gtgaccccgcagaagcagcagcgcctggccagtcgctggcgtagcgacgacgacgacgat cctccgctgagtggagacgaccctctggtcgggggcttcggcttcagcttccgttccaag tgcctggaggagcggcggggcaagggccgcgcggccgacgagctggaggccggtgccgtc gaggacgacgaagagtccggggatggcggtagctcagcaggttcgggctcggcgcccggc gcggtgctgtcgctgggcgcttgctgcctggcactgctgcagatattccgctccaagaag ttcccgtcggacaagctggagcggctgtaccagcgctacttcttccgtctgaaccagagc agcctcactatgctcatggctgtgctggtgctagtgtgcctcgtcatgttggcctttcac gctgcgcggcccccgctccagctgccctacctggccgtgctggtggccgcggtgagtgtg atcctcgtcatggccgtgctctgcaaccgtgccgccttccaccaggaccacatgggcctg gcctgctacgcgctcatagccgtggtgctggccgtccaggtggtgggcctcttgctgccc cagccacgcagcgcctccgaaggcatctggtggaccgtgttcttcatctataccatctac acgctcctgcctgtgcgcatgcgggccgcggtactcagcggggtgctcctgtctgccctc cacctggccattgccctgcgcaccaacgcccaggaccagttcttgctcaagcagcttgtc tccaatgtcctcattttctcctgcaccaacatcgtgggtgtctgtacccactacccggct gaggtctcccagagacaggccttccaggagacccgggagtgcatccaggcgcggctccat tcacagcgggagaatcagcagcaggagcggctcctgctgtctgtccttccccgtcacgtt gccatggagatgaaagcagacatcaacgccaagcaggaggatatgatgttccataagatt tacatccagaaacatgacaacgtgagcatcctgtttgcggacattgagggcttcaccagt ctggcatcccagtgcactgcccaggagctggtcatgaccctcaatgagctctttgcccgc tttgacaagctggctgcggagaatcactgtttacgtattaagatcctgggagattgctat tactgcgtctcggggctgcctgaagcgagggctgaccatgcccactgctgcgtggagatg ggcatggacatgattgaggccatctcgctggtccgggaggtgacgggtgtgaacgtgaac atgcgtgtgggaatccacagcgggcgagtgcactgcggtgtccttggtctcaggaagtgg cagttcgacgtctggtccaacgacgtcacgctggccaaccacatggaggctggaggcaag gcaggacgcatccatatcaccaaggccacactcaactacttgaatggcgactacgaagtg gagccaggctgtgggggcgagcgcaacgcctacctcaaggagcacagcatcgagaccttc ctcatcctgcgctgcacccagaagcggaaagaagagaaggccatgattgccaagatgaat cgccagagaaccaactccatcgggcacaacccgccacactggggggctgagcgccccttc tacaaccacttgggtggcaaccaggtgtccaaggagatgaagcggatgggttttgaagac cccaaggacaagaacgcccaggaaagtgcaaaccccgaggatgaagtggacgaatttctg ggccgtgccattgacgccaggagcatcgacaggctgcggtctgagcatgtccgcaagttc ctcttgaccttcagggagcctgacttagagaagaagtactccaagcaggtggatgaccga ttcggtgcctatgtggcatgtgcctcgctcgtcttcctcttcatctgctttgtccagatc accatcgtgccccactctgtgttcatgctgagtttctatctgacctgtttcctgctgctg accttggtggtgtttgtgtccgtgatctactcctgcgtgaagctctttccggccccgctg cagaccctctccaggaagatcgtacggtccaagatgaacagcaccctggtgggggtgttc accatcaccctggtgttcctgtcggcttttgtcaacatgttcacctgcaactccaaggac ctgtttggctgcctggcagatgagcacaatgtcagcgtcagccaagtcaacgcgtgccat gtggtggagtcggccgtcaactacagcctgggggacgagcggggcttctgcggcagctcc tggcccaactgcaacttccccgagtacttcacctacagcgtgctgctctgcctgctggcc tgctccgtgttcctgcagatcagctgcattgggaagctggtgctcatgctggccattgag ctcgtctacgtgctggtcgtcgaggtgcctggtgtcacactctttgacaacgccgacctg ctggtcaccgccaacgccatagacttcagcaacaacgggacctcccagtgccctgagcac gcgaccaaggtggcactgaaggtggtgacgcccatcatcatctccgtcttcgtgctggcc ctgtacctgcatgcccagcaggtggagtccaccgcccgccttgacttcctctggaaactg caggccacggaggagaaggaagagatggaggagttgcaggcctacaaccggcggctgctg cacaacatcctgcccaaggacgtggctgcgcacttcctggcccgcgagcggcgcaacgac gagctctactaccagtcgtgcgagtgcgtggccgtcatgttcgcctccatcgccaacttc tccgagttctacgtggagctggaggccaacaacgagggcgttgagtgcctgcggctgctc aacgagatcattgccgacttcgatgagatcatcagcgaggatcggttcagacagctagaa aagatcaagaccattggcagcacctacatggccgcctcaggcctcaacgactccacctac gacaaggtgggcaagacccacatcaaagctctcgctgacttcgccatgaagctgatggac caaatgaagtacatcaacgagcactcgttcaacaacttccagatgaagattgggcttaat attggccccgtggtggcaggggttattggggcccgcaagcctcagtacgacatctggggc aatacagtgaacgtggccagccgcatggacagtactggtgtgcccgaccgcatccaggtg agtgcaggaacatccaccccacccacatgggggcctctgtgtgttgctaagtggtcttct agcagcccccacagttgccagtcagaatttctgcagccgatttga

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