Vicugna pacos (alpaca): 102535401 Help Entry 102535401         CDS       T08098                                  Symbol ADCY9 Name (RefSeq) adenylate cyclase type 9   KO K08049   adenylate cyclase 9 [EC:4.6.1.1] Organism vpc  Vicugna pacos (alpaca) Pathway vpc00230   Purine metabolism vpc01100   Metabolic pathways vpc01522   Endocrine resistance vpc04015   Rap1 signaling pathway vpc04020   Calcium signaling pathway vpc04022   cGMP-PKG signaling pathway vpc04024   cAMP signaling pathway vpc04062   Chemokine signaling pathway vpc04072   Phospholipase D signaling pathway vpc04114   Oocyte meiosis vpc04211   Longevity regulating pathway vpc04213   Longevity regulating pathway - multiple species vpc04261   Adrenergic signaling in cardiomyocytes vpc04270   Vascular smooth muscle contraction vpc04371   Apelin signaling pathway vpc04540   Gap junction vpc04611   Platelet activation vpc04713   Circadian entrainment vpc04714   Thermogenesis vpc04723   Retrograde endocannabinoid signaling vpc04724   Glutamatergic synapse vpc04725   Cholinergic synapse vpc04727   GABAergic synapse vpc04750   Inflammatory mediator regulation of TRP channels vpc04911   Insulin secretion vpc04912   GnRH signaling pathway vpc04913   Ovarian steroidogenesis vpc04914   Progesterone-mediated oocyte maturation vpc04915   Estrogen signaling pathway vpc04916   Melanogenesis vpc04918   Thyroid hormone synthesis vpc04921   Oxytocin signaling pathway vpc04923   Regulation of lipolysis in adipocytes vpc04925   Aldosterone synthesis and secretion vpc04926   Relaxin signaling pathway vpc04927   Cortisol synthesis and secretion vpc04928   Parathyroid hormone synthesis, secretion and action vpc04934   Cushing syndrome vpc04935   Growth hormone synthesis, secretion and action vpc04961   Endocrine and other factor-regulated calcium reabsorption vpc04962   Vasopressin-regulated water reabsorption vpc04970   Salivary secretion vpc04971   Gastric acid secretion vpc04972   Pancreatic secretion vpc04976   Bile secretion vpc05032   Morphine addiction vpc05163   Human cytomegalovirus infection vpc05166   Human T-cell leukemia virus 1 infection vpc05200   Pathways in cancer vpc05207   Chemical carcinogenesis - receptor activation vpc05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:vpc00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102535401 (ADCY9)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102535401 (ADCY9)    04371 Apelin signaling pathway     102535401 (ADCY9)    04020 Calcium signaling pathway     102535401 (ADCY9)    04072 Phospholipase D signaling pathway     102535401 (ADCY9)    04024 cAMP signaling pathway     102535401 (ADCY9)    04022 cGMP-PKG signaling pathway     102535401 (ADCY9)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102535401 (ADCY9)   09144 Cellular community - eukaryotes    04540 Gap junction     102535401 (ADCY9)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102535401 (ADCY9)    04062 Chemokine signaling pathway     102535401 (ADCY9)   09152 Endocrine system    04911 Insulin secretion     102535401 (ADCY9)    04923 Regulation of lipolysis in adipocytes     102535401 (ADCY9)    04912 GnRH signaling pathway     102535401 (ADCY9)    04913 Ovarian steroidogenesis     102535401 (ADCY9)    04915 Estrogen signaling pathway     102535401 (ADCY9)    04914 Progesterone-mediated oocyte maturation     102535401 (ADCY9)    04921 Oxytocin signaling pathway     102535401 (ADCY9)    04926 Relaxin signaling pathway     102535401 (ADCY9)    04935 Growth hormone synthesis, secretion and action     102535401 (ADCY9)    04918 Thyroid hormone synthesis     102535401 (ADCY9)    04928 Parathyroid hormone synthesis, secretion and action     102535401 (ADCY9)    04916 Melanogenesis     102535401 (ADCY9)    04925 Aldosterone synthesis and secretion     102535401 (ADCY9)    04927 Cortisol synthesis and secretion     102535401 (ADCY9)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102535401 (ADCY9)    04270 Vascular smooth muscle contraction     102535401 (ADCY9)   09154 Digestive system    04970 Salivary secretion     102535401 (ADCY9)    04971 Gastric acid secretion     102535401 (ADCY9)    04972 Pancreatic secretion     102535401 (ADCY9)    04976 Bile secretion     102535401 (ADCY9)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     102535401 (ADCY9)    04961 Endocrine and other factor-regulated calcium reabsorption     102535401 (ADCY9)   09156 Nervous system    04724 Glutamatergic synapse     102535401 (ADCY9)    04727 GABAergic synapse     102535401 (ADCY9)    04725 Cholinergic synapse     102535401 (ADCY9)    04723 Retrograde endocannabinoid signaling     102535401 (ADCY9)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102535401 (ADCY9)   09149 Aging    04211 Longevity regulating pathway     102535401 (ADCY9)    04213 Longevity regulating pathway - multiple species     102535401 (ADCY9)   09159 Environmental adaptation    04713 Circadian entrainment     102535401 (ADCY9)    04714 Thermogenesis     102535401 (ADCY9)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102535401 (ADCY9)    05207 Chemical carcinogenesis - receptor activation     102535401 (ADCY9)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102535401 (ADCY9)    05163 Human cytomegalovirus infection     102535401 (ADCY9)   09165 Substance dependence    05032 Morphine addiction     102535401 (ADCY9)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102535401 (ADCY9)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102535401 (ADCY9)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102535401 (ADCY9) Enzymes [BR:vpc01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102535401 (ADCY9) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom Motif Other DBs NCBI-GeneID:  102535401 NCBI-ProteinID:  XP_006204380 UniProt:  A0A6I9I7G7 LinkDB All DBs Position 18 AA seq 1353 aa AA seqDB search MASPPHQQLLQHHSTEVSCDSSGDSNSVRVKINPKQLSSNSHPKHCKYSISSSCSSSGDS GGIPRRMGAGGRLRRQKKLPQLFERASSRWWDPKFDSVNLEEACMERCFPQTQRRFRYAL FYIGFACLLWSIYFGVHMRSKLIVMVVPALCFLVVCVGFFLFTFTKLYARHYVWTSLVLT LLVFALTLAAQFQVLTPLSGRVDSSNHTPAAKSADTCLSQVGSFSMCIEVLFLLYTVMHL PLYLSLILGVAYSVLFETFGYHFRDEDCFPWPGAGAPQWELLSRALLHVCVHAIGIHLFI MSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKR HATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLN DLFGRFDQLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIRAIEQFCQEK KEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLD DRYEMEDGKVTERLGQSVVADQLKGLKTYLIAGQRAKESHCSCSEALLSGFEVIDGSRVS SGPRGQGTASPGSVSDLAQTVKTFDNLKTCPSCGITFAPTSEAGAEGGAVQNGCQEEQKN SAKASGGPSSKTQNGLLSPPPEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNI REKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELERAYRTSYQAEVIKNSPVKTF ASPTFSSLLDVLLSTTVFLILSVTCFLKYGAVSTPPPPAALAVFCAALLLEVLSLVVSVR MVFFLEDVMACTKRLLEWIAGWLPRHFIGAILVSLPALAVYSHVTSEFETNIHSTVLTGS AVLISVVHYCNFCQLSSWMRSSLATVVGAGPLLLLYVSLCPDSSIVISDLAAVQNFSSAR SPCNASLLHDSRKPASLIGQEVILVIFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTK IQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDNGGVIFASIVNFSEFYEENYEGGKE CYRVLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNATQCRDGGHPQEHLQILFE FAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTT GVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCTDSGMVPQHQLSISP DIRVQVDGSIGRSPTDEIANLVPSVQNPDQASLGSDHNLQAKDVHLTSKRPWKEPIKAEE RCRFGKAIEKSDYDEMGLEETSELTKLNVSQRV NT seq 4062 nt NT seq  +upstreamnt  +downstreamnt atggcttccccgccccaccagcagctgctgcagcaccacagcaccgaggtgagttgtgac tccagcggagacagcaacagcgtgagggtcaaaatcaaccccaagcagctgtcctccaac agccaccccaaacattgcaagtacagcatctcctccagctgtagcagctccggggactca ggagggatccccaggagaatgggcgccggaggccgcctgcgcaggcagaagaagctgccc cagctgttcgagagggcctccagccggtggtgggaccccaagtttgactctgtgaacttg gaggaggcttgcatggagcgctgcttcccgcagacccagcgtcgcttccggtatgcgctg ttctacatcggcttcgcctgccttctctggagcatctattttggggtacatatgagatcc aaattgattgtcatggtagtccctgctctgtgcttcctcgtggtgtgtgtgggctttttt ctgtttaccttcaccaagctgtatgcccggcattatgtgtggacctcgctggttctcact ctcctggtgtttgccctgaccctggctgcccagtttcaggtcttgacgcctctctcagga cgagttgacagttccaatcatactcctgcagccaagtcggcagacacttgcttatctcaa gtggggagcttttccatgtgcattgaagtgctctttttgctctacaccgtcatgcactta cctttgtatttgagcttgattttgggagtggcctattctgttctttttgagacctttggg tatcatttccgagacgaagactgcttcccctggcctggagcgggggccccacagtgggag ctgctgagccgagccctgctccatgtctgtgttcatgccatcgggatccacctgttcatc atgtcacaggtgagatccaggagcaccttcctcaaggtgggacagtccatcatgcatggg aaggatctggaagtggaaaaagccctgaaagagaggatgattcattctgtgatgccaaga attatagctgatgacttgatgaaacagggggacgaggagagtgagaattctgttaaaagg cacgccacctccagccccaagaacaggaagaaaaagtcttccatacagaaagcccccatt gcgttccgcccgtttaagatgcagcagatcgaagaagtcagtattttatttgcagatatc gtgggcttcaccaagatgagtgccaacaagtccgcccatgccctggtgggtctcctcaac gatttgtttggccgctttgaccagttgtgtgaggagaccaagtgtgagaaaatcagtacc ctgggagactgctactactgtgtggctgggtgtccggaaccccgggccgaccatgcctac tgctgcatcgaaatgggcttgggcatgataagagccatcgagcagttctgccaggagaag aaagagatggtgaacatgcgtgttggggttcacacggggaccgtcttgtgtggcatcttg ggcatgaggaggtttaaatttgatgtgtggtccaatgatgtaaacctggccaatctcatg gagcagctgggagtggctggcaaggttcacatttccgaggccactgcaaaatacctagat gaccggtacgaaatggaagatgggaaggttactgagcgtctcggccagagtgtggttgct gaccagttgaaaggtttgaagacatacctgatagcgggtcagagagcgaaggagtctcat tgcagctgttcagaggccttgctttctggctttgaggtcattgacggctcgcgggtgtcc tcaggccctaggggacaggggacagcatcgccagggagtgtcagtgacttggcgcagact gtcaaaacctttgataaccttaagacctgcccttcatgtggaatcacatttgctcccaca tcagaggccggcgcagaaggcggggcggtccagaacggctgccaggaggagcagaagaac agcgccaaggcttccggagggcccagctccaagacacagaatggactgctcagtcctccc cccgaggagaagctcaccaacagccagacctccctgtgtgagatcttgcaggagaaggga aggtgggcaggtgtgagcttggaccagtcggctctccttccgctgagattcaagaacatt cgggagaaaacagatgcccactttgtggacgtcatcaaggaggacagcctgatgaaagat tatttttttaagccgcctattaatcagttcagcttgaacttcctggatcaggagctagag agagcctacaggaccagctaccaggcagaggttataaagaattctcccgtgaagactttt gccagtcccaccttcagctctctcctggatgtgcttctgtcaacgacagtgtttctgatt ctctctgttacctgcttcctgaagtatggggctgtctccacgccgcccccgccggctgct ctggcggtcttctgtgcggccctgctgctggaggtgctatccctcgtggtctccgtcagg atggtgttcttcctggaggatgtgatggcttgtaccaagcgcctgctggagtggatagcc ggctggctcccacgccatttcattggggccatcctggtgtcccttcccgctctcgcggtc tattcacacgtcacctccgaatttgagacaaacatacactccaccgtgctcacgggctcg gctgtcctgatctccgtggtgcactactgtaacttctgccagctcagctcctggatgagg tcctccttagccaccgtcgtcggggccgggcctttgctgctgctctatgtgtccctgtgc ccggacagttccatagtaatttcagaccttgctgcagtacagaatttcagctctgcaagg agtccgtgcaatgcttcgctgctgcatgacagcaggaaaccagccagcctgattggccag gaggtgattcttgtcatctttctcctgcttttgctggtctggttcctgaatcgagagttt gaagtcagctaccgcctgcactaccacggggacgtggaggcggacctgcaccgcaccaag atccagagcatgagggaccaagccgactggctgctgaggaacatcatcccctaccacgtg gctgagcagctgaaggtctcccagacctactccaagaaccacgacaacggaggcgtcatc ttcgccagcatcgtcaacttcagcgagttctacgaggagaactatgagggcggcaaggag tgctaccgggtcctcaacgagctgattggggacttcgacgagctcctgagcaagccggac tacagcagcatcgagaagatcaagaccatcggggccacatacatggcggcgtcggggctg aatgccacgcagtgccgggatggcggccacccgcaggagcacctgcagatcctcttcgag ttcgccaaggagatgatgcgcgtggtggatgacttcaacaacaacatgctctggttcaac ttcaagctcagggtgggcttcaaccatggacccctcacggcgggcgtcattggcaccacc aagctgctgtacgacatctggggtgacacggtcaacattgccagccggatggacaccacg ggggtggagtgccgcatccaggtgagcgaggagagctaccgcgtcctgagcaagatgggc tacgacttcgactacagggggacagtgaacgtcaagggcaaaggccagatgaagacctac ctttaccccaagtgcacggacagcgggatggtgccgcagcaccagctgtccatctcccct gacatccgcgtccaggtggacggcagcatcggtcgctctcccacggacgagatcgccaac ctggtgccttccgtgcagaacccggaccaggcgtccctgggttccgatcacaacctgcag gccaaggacgtacacctgacttcgaagagaccctggaaggagcccatcaaagccgaagaa aggtgtcggttcggcaaagccatagagaaaagcgactatgatgaaatggggctggaggag accagcgagctcaccaagctcaacgtctcgcagagggtgtga

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