Vicugna pacos (alpaca): 102539212
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Entry
102539212 CDS
T08098
Symbol
IKBKE
Name
(RefSeq) inhibitor of nuclear factor kappa-B kinase subunit epsilon
KO
K07211
inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:
2.7.11.10
]
Organism
vpc
Vicugna pacos (alpaca)
Pathway
vpc04620
Toll-like receptor signaling pathway
vpc04621
NOD-like receptor signaling pathway
vpc04622
RIG-I-like receptor signaling pathway
vpc04623
Cytosolic DNA-sensing pathway
vpc04625
C-type lectin receptor signaling pathway
vpc04657
IL-17 signaling pathway
vpc04936
Alcoholic liver disease
vpc05160
Hepatitis C
vpc05161
Hepatitis B
vpc05162
Measles
vpc05164
Influenza A
vpc05165
Human papillomavirus infection
vpc05167
Kaposi sarcoma-associated herpesvirus infection
vpc05168
Herpes simplex virus 1 infection
vpc05169
Epstein-Barr virus infection
vpc05171
Coronavirus disease - COVID-19
vpc05207
Chemical carcinogenesis - receptor activation
vpc05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
vpc00001
]
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
102539212 (IKBKE)
04621 NOD-like receptor signaling pathway
102539212 (IKBKE)
04622 RIG-I-like receptor signaling pathway
102539212 (IKBKE)
04623 Cytosolic DNA-sensing pathway
102539212 (IKBKE)
04625 C-type lectin receptor signaling pathway
102539212 (IKBKE)
04657 IL-17 signaling pathway
102539212 (IKBKE)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
102539212 (IKBKE)
09172 Infectious disease: viral
05161 Hepatitis B
102539212 (IKBKE)
05160 Hepatitis C
102539212 (IKBKE)
05171 Coronavirus disease - COVID-19
102539212 (IKBKE)
05164 Influenza A
102539212 (IKBKE)
05162 Measles
102539212 (IKBKE)
05168 Herpes simplex virus 1 infection
102539212 (IKBKE)
05167 Kaposi sarcoma-associated herpesvirus infection
102539212 (IKBKE)
05169 Epstein-Barr virus infection
102539212 (IKBKE)
05165 Human papillomavirus infection
102539212 (IKBKE)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102539212 (IKBKE)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
102539212 (IKBKE)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
vpc01001
]
102539212 (IKBKE)
Enzymes [BR:
vpc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
102539212 (IKBKE)
Protein kinases [BR:
vpc01001
]
Serine/threonine kinases: Other
IKK family [OT]
102539212 (IKBKE)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
TBK1_CCD1
Pkinase
TBK1_ULD
PK_Tyr_Ser-Thr
ABC1
Pkinase_fungal
Kinase-like
RH_dom
Motif
Other DBs
NCBI-GeneID:
102539212
NCBI-ProteinID:
XP_006215529
UniProt:
A0A6I9IKS4
LinkDB
All DBs
Position
23
AA seq
718 aa
AA seq
DB search
MQSTVNYLWHTDDLLGQGATASVYKARNKKSGELVAVKVFNTASYLRPREVQVREFEVLR
KLNHQNIIKLFAVEETGGSRQKVLVMEYCSSGSLLNVLESPENAFGLPEDEFLVVLRCVV
AGMNHLRENGVVHRDIKPGNIMRLVGEEGQSIYKLTDFGAARELGDDEHFVSVYGTEEYL
HPDMYERAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFVPFGGPRRNKEIMYRITTE
KPAGAIAGTQRRENGPLEWSYTLPITCQLSTGLQSQLVPILANILEVEQAKCWGFDQFFA
ETSDILQRVIVHVFSLPQAILHHVYVHAHNTIAIFLEAVYKQTNVAPQHQEYLFEGHLCV
LEPSLSAQHIVHTTASSPLTLFSMASETPKGLAFRDPALDIPKFVPKVDLQADYNTAKGV
LGAGYQALRLARSLLAGQELMLRGLHWFTEILQATCRRTLEVTRMALLFLSSSLGTERFG
SVAGGPELQELMRVAELRAKLRTLAEVLSRCSHNITETQMTLSSLSSELGKNRDQVHEDR
SIQQIQCCLDKMYLIYKQFKKSRMRPGLGYNEEQIHKLDKVNFSHLAKRLLQVFQEEHVQ
KYQASLATHGKRMRVVHETRNHLRLVGCSVAACNTEAQGAQESLSKILDRLSHQLLQDRT
QGAGASSPPAAPYPSPALRELTLHMQELCEEMKLLSSDLQDNNRIIEGLSRVPSAPDI
NT seq
2157 nt
NT seq
+upstream
nt +downstream
nt
atgcagagcaccgtcaattacctgtggcacacggatgacctgctggggcagggcgccact
gccagtgtgtacaaggcccgaaacaagaaatctggggagctggttgctgtgaaagtcttc
aacactgccagctacctgcgaccccgggaggtgcaggtgagggagttcgaggtcctgcgg
aagctgaaccatcagaacatcatcaagctctttgcagtggaggagacggggggcagcagg
cagaaggtgctggtgatggagtactgctccagcgggagtctgctcaatgtgctggagagc
cctgagaacgccttcgggctgccggaggacgagttcctggtggtcctgcgctgtgtggtg
gccggcatgaaccacctgcgggagaacggcgtcgtgcaccgagacatcaagccggggaac
atcatgcgcctggtgggcgaggagggccagagcatctacaagctgacggacttcggggcc
gcccgggagctgggcgatgacgagcatttcgtgtcggtctacggcactgaggagtacctg
catcctgacatgtatgagcgggcagtgcttcgcaagccccagcagaaggcttttggggtg
accgtggatctctggagcattggggtgaccctgtaccacgcagccaccggcagcctgccc
ttcgtccccttcggcgggcctcggcgcaacaaggagatcatgtaccggatcaccacggag
aagccggccggggccattgcgggcactcagaggcgggagaacgggcccctggagtggagc
tacaccctccccatcacctgccagctgtccacagggctgcagagccagttggtgcccatc
ctggcaaacatcctggaagtggagcaggccaagtgctggggcttcgaccagttctttgcg
gagaccagtgacatcctgcagcgagtcatcgtccacgtcttctccctgccccaggccatc
ctgcaccacgtctatgtccacgcacacaacacgatagccatctttctggaggccgtgtac
aagcagaccaacgtggccccccagcaccaggagtacctctttgagggtcacctctgtgtc
ctcgagcccagcctctcagcacagcacatcgtccacaccacagcaagcagccccctcacc
ctgttcagcatggccagtgagacccccaagggtctggccttcagggaccctgctctggac
atccccaagttcgtcccaaaagtggacctgcaggcagattacaacacggctaagggggtg
ttgggggccggctaccaggccctgcggctggcacggtccctgctggcggggcaggagctg
atgcttcgggggctgcactggttcacggagattctccaggccacgtgcaggcggacgctg
gaggtcaccaggatggccctcctcttcctcagcagcagcctgggcaccgagaggttcggc
agcgtggctggggggcctgagctccaggaactgatgagagttgcagagctgagggccaag
ctgcggactttggctgaggtcctctccagatgttcccacaatatcacagagacccagatg
accctgagcagcctgagctctgagctggggaagaaccgggatcaggtacatgaggacaga
agcatccagcagattcagtgttgtttggacaagatgtatcttatctacaaacagttcaag
aaatccaggatgaggccagggcttggctacaatgaggagcagattcacaagctggataag
gtgaattttagtcatttagccaaaaggctcctgcaggtgttccaggaggagcacgtgcag
aagtaccaggcatcgctggccacacacggcaagaggatgagggtggtgcatgagaccagg
aaccacctgcgcctggttggctgttctgtggctgcctgtaacaccgaagcccagggagcg
caggagagcctcagcaagatccttgaccggctatcgcatcagctcctccaggacagaaca
cagggggctggggcctcatcgccccctgcagccccttatcccagccctgcactaagggag
ctgactctgcacatgcaggagctctgcgaggagatgaagctgctgtcgtctgacctccag
gacaacaaccgcatcattgaagggttaagtcgggtcccatcggctcctgacatctga
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