KEGG   Vicugna pacos (alpaca): 102540698
Entry
102540698         CDS       T08098                                 
Symbol
MAPK14
Name
(RefSeq) mitogen-activated protein kinase 14
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
vpc  Vicugna pacos (alpaca)
Pathway
vpc01522  Endocrine resistance
vpc04010  MAPK signaling pathway
vpc04015  Rap1 signaling pathway
vpc04068  FoxO signaling pathway
vpc04071  Sphingolipid signaling pathway
vpc04114  Oocyte meiosis
vpc04148  Efferocytosis
vpc04218  Cellular senescence
vpc04261  Adrenergic signaling in cardiomyocytes
vpc04370  VEGF signaling pathway
vpc04380  Osteoclast differentiation
vpc04550  Signaling pathways regulating pluripotency of stem cells
vpc04611  Platelet activation
vpc04613  Neutrophil extracellular trap formation
vpc04620  Toll-like receptor signaling pathway
vpc04621  NOD-like receptor signaling pathway
vpc04622  RIG-I-like receptor signaling pathway
vpc04625  C-type lectin receptor signaling pathway
vpc04657  IL-17 signaling pathway
vpc04658  Th1 and Th2 cell differentiation
vpc04659  Th17 cell differentiation
vpc04660  T cell receptor signaling pathway
vpc04664  Fc epsilon RI signaling pathway
vpc04668  TNF signaling pathway
vpc04670  Leukocyte transendothelial migration
vpc04714  Thermogenesis
vpc04722  Neurotrophin signaling pathway
vpc04723  Retrograde endocannabinoid signaling
vpc04728  Dopaminergic synapse
vpc04750  Inflammatory mediator regulation of TRP channels
vpc04912  GnRH signaling pathway
vpc04914  Progesterone-mediated oocyte maturation
vpc04917  Prolactin signaling pathway
vpc04926  Relaxin signaling pathway
vpc04932  Non-alcoholic fatty liver disease
vpc04933  AGE-RAGE signaling pathway in diabetic complications
vpc04935  Growth hormone synthesis, secretion and action
vpc04936  Alcoholic liver disease
vpc05014  Amyotrophic lateral sclerosis
vpc05020  Prion disease
vpc05022  Pathways of neurodegeneration - multiple diseases
vpc05132  Salmonella infection
vpc05133  Pertussis
vpc05135  Yersinia infection
vpc05140  Leishmaniasis
vpc05142  Chagas disease
vpc05145  Toxoplasmosis
vpc05152  Tuberculosis
vpc05161  Hepatitis B
vpc05163  Human cytomegalovirus infection
vpc05167  Kaposi sarcoma-associated herpesvirus infection
vpc05169  Epstein-Barr virus infection
vpc05170  Human immunodeficiency virus 1 infection
vpc05171  Coronavirus disease - COVID-19
vpc05205  Proteoglycans in cancer
vpc05208  Chemical carcinogenesis - reactive oxygen species
vpc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
vpc05415  Diabetic cardiomyopathy
vpc05417  Lipid and atherosclerosis
vpc05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:vpc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102540698 (MAPK14)
   04015 Rap1 signaling pathway
    102540698 (MAPK14)
   04370 VEGF signaling pathway
    102540698 (MAPK14)
   04668 TNF signaling pathway
    102540698 (MAPK14)
   04068 FoxO signaling pathway
    102540698 (MAPK14)
   04071 Sphingolipid signaling pathway
    102540698 (MAPK14)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    102540698 (MAPK14)
  09143 Cell growth and death
   04114 Oocyte meiosis
    102540698 (MAPK14)
   04218 Cellular senescence
    102540698 (MAPK14)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    102540698 (MAPK14)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102540698 (MAPK14)
   04613 Neutrophil extracellular trap formation
    102540698 (MAPK14)
   04620 Toll-like receptor signaling pathway
    102540698 (MAPK14)
   04621 NOD-like receptor signaling pathway
    102540698 (MAPK14)
   04622 RIG-I-like receptor signaling pathway
    102540698 (MAPK14)
   04625 C-type lectin receptor signaling pathway
    102540698 (MAPK14)
   04660 T cell receptor signaling pathway
    102540698 (MAPK14)
   04658 Th1 and Th2 cell differentiation
    102540698 (MAPK14)
   04659 Th17 cell differentiation
    102540698 (MAPK14)
   04657 IL-17 signaling pathway
    102540698 (MAPK14)
   04664 Fc epsilon RI signaling pathway
    102540698 (MAPK14)
   04670 Leukocyte transendothelial migration
    102540698 (MAPK14)
  09152 Endocrine system
   04912 GnRH signaling pathway
    102540698 (MAPK14)
   04914 Progesterone-mediated oocyte maturation
    102540698 (MAPK14)
   04917 Prolactin signaling pathway
    102540698 (MAPK14)
   04926 Relaxin signaling pathway
    102540698 (MAPK14)
   04935 Growth hormone synthesis, secretion and action
    102540698 (MAPK14)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102540698 (MAPK14)
  09156 Nervous system
   04728 Dopaminergic synapse
    102540698 (MAPK14)
   04723 Retrograde endocannabinoid signaling
    102540698 (MAPK14)
   04722 Neurotrophin signaling pathway
    102540698 (MAPK14)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102540698 (MAPK14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102540698 (MAPK14)
  09159 Environmental adaptation
   04714 Thermogenesis
    102540698 (MAPK14)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    102540698 (MAPK14)
   05208 Chemical carcinogenesis - reactive oxygen species
    102540698 (MAPK14)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102540698 (MAPK14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102540698 (MAPK14)
   05161 Hepatitis B
    102540698 (MAPK14)
   05171 Coronavirus disease - COVID-19
    102540698 (MAPK14)
   05163 Human cytomegalovirus infection
    102540698 (MAPK14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102540698 (MAPK14)
   05169 Epstein-Barr virus infection
    102540698 (MAPK14)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102540698 (MAPK14)
   05135 Yersinia infection
    102540698 (MAPK14)
   05133 Pertussis
    102540698 (MAPK14)
   05152 Tuberculosis
    102540698 (MAPK14)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    102540698 (MAPK14)
   05140 Leishmaniasis
    102540698 (MAPK14)
   05142 Chagas disease
    102540698 (MAPK14)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    102540698 (MAPK14)
   05020 Prion disease
    102540698 (MAPK14)
   05022 Pathways of neurodegeneration - multiple diseases
    102540698 (MAPK14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102540698 (MAPK14)
   05418 Fluid shear stress and atherosclerosis
    102540698 (MAPK14)
   05415 Diabetic cardiomyopathy
    102540698 (MAPK14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    102540698 (MAPK14)
   04932 Non-alcoholic fatty liver disease
    102540698 (MAPK14)
   04933 AGE-RAGE signaling pathway in diabetic complications
    102540698 (MAPK14)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    102540698 (MAPK14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:vpc01001]
    102540698 (MAPK14)
Enzymes [BR:vpc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     102540698 (MAPK14)
Protein kinases [BR:vpc01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   102540698 (MAPK14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kinase-like
Other DBs
NCBI-GeneID: 102540698
NCBI-ProteinID: XP_006202133
UniProt: A0A6I9I4C0
LinkDB
Position
20
AA seq 283 aa
MKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRG
LKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNW
MHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARN
YIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDE
PVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
NT seq 852 nt   +upstreamnt  +downstreamnt
atgaaacatgaaaatgtgattggtctgttggatgttttcacacctgcaaggtcgttggag
gaattcaatgatgtgtatctggtgacccatctcatgggggcagatctgaacaacattgtg
aaatgtcagaagcttacggatgaccacgttcagttcctcatctaccaaattctccgaggt
ctcaagtatatacattcagctgacataattcacagggacctaaaacctagtaatctagct
gtgaatgaagactgtgagctgaagatcttggattttggactggctcggcatacagatgat
gaaatgacaggctatgtggccactaggtggtacagggctcctgagatcatgctgaactgg
atgcattacaaccagacagttgatatttggtcagttggatgtatcatggctgagctgttg
actggaagaacattgtttcctggtacagaccatattgatcagttgaagctcattttaaga
ctcgttggaaccccaggggctgagcttttgaagaaaatctcctcagagtctgcaagaaac
tacattcaatcattgactcagatgccgaagatgaactttgcaaatgtatttattggtgcc
aatcccttggctgtcgacttgctggagaagatgctcgtattggactcagataagaggatt
accgcggcccaagccctggcacatgcctactttgctcagtaccacgatcctgacgatgaa
cccgtggctgatccttatgatcagtcttttgaaagcagggacctccttatagatgagtgg
aaaagcctgacctatgatgaagtcatcagctttgtgccgccaccccttgaccaagaagag
atggagtcttga

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