Vicugna pacos (alpaca): 102544796
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Entry
102544796 CDS
T08098
Symbol
TH
Name
(RefSeq) LOW QUALITY PROTEIN: tyrosine 3-monooxygenase
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
vpc
Vicugna pacos (alpaca)
Pathway
vpc00350
Tyrosine metabolism
vpc00790
Folate biosynthesis
vpc01100
Metabolic pathways
vpc04728
Dopaminergic synapse
vpc04917
Prolactin signaling pathway
vpc05012
Parkinson disease
vpc05030
Cocaine addiction
vpc05031
Amphetamine addiction
vpc05034
Alcoholism
Module
vpc_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
vpc00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
102544796 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
102544796 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
102544796 (TH)
09156 Nervous system
04728 Dopaminergic synapse
102544796 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
102544796 (TH)
09165 Substance dependence
05030 Cocaine addiction
102544796 (TH)
05031 Amphetamine addiction
102544796 (TH)
05034 Alcoholism
102544796 (TH)
Enzymes [BR:
vpc01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
102544796 (TH)
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Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
102544796
NCBI-ProteinID:
XP_031546431
UniProt:
A0A6J3BPS2
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All DBs
Position
25
AA seq
458 aa
AA seq
DB search
MPTPSATTPQAKGFRRAVSELDAKQAEAIMVRGQERDGKALLNLLFSLRPTRPPSLSRAV
KALETFEAQIHHLETRPAQKPRAGGPQLEYFVRCEVPSTALPALLSSVRRVAEDVRGVGE
NKVLWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQAYRQRRKAIAAIAFQYKQGDPIP
HVEYTAEETATWKQVYSTLRGLYTTHACREYLEAFELLEQFCGYQEDRIPQLEDVSRFLR
ERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLA
DRTFAQFSQDIGLASLGVSDEEIEKLSTLYWFTVEFGLCKQNGQVKAYGAGLLSSYGELL
HSLSEEPEVRAFDPDAAAVCPSSSPSPQCLRVPTGXQGVCAAPPTRSYASRIQRPFSVKF
DPYTLAIDVLDSPHAIRRSLEGIQDELHTLAHALNAIS
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
atgcccactcccagcgccaccacgccgcaggccaagggcttccgccgggccgtctccgag
ctggacgccaagcaggccgaggccatcatggtaagaggacaggagcgggacggcaaggcc
ctgctgaacctgctcttctccctgcggcccaccaggccgccctcgctgtcccgggccgtg
aaggcgctggagacatttgaagcccaaatccatcacctggagacgcggccagcccagaag
ccacgggcggggggcccacagctggagtactttgtgcgctgtgaggtgcccagcaccgcc
ctgcccgctctgctcagctccgtgcgccgggtggcagaagatgtgcgtggtgttggggag
aacaaggtcctctggttcccaaggaaggtttctgagctggacaagtgtcaccacctggtc
accaagtttgaccctgacctggacttggatcacccgggcttctcggaccaggcgtaccgc
cagcgcaggaaggcgatcgccgcgattgccttccagtacaagcaaggtgaccctattccc
cacgtggagtacacggccgaggagactgccacctggaagcaggtctactccaccctacgg
ggtctctacaccacccacgcctgccgggagtacctggaggccttcgagctgctggagcag
ttctgcgggtaccaggaggaccgcatcccccagctggaggacgtctcccgcttcctgagg
gagaggaccggcttccagctgcggcccgtggccggcctgctgtccgcccgggacttcctg
gccagcctggccttccgggtgttccagtgcacccagtacatccgccacgcctcctccccc
atgcactccccggagccggactgctgccacgagctgctggggcatgtgcccatgctggcc
gaccggaccttcgcccagttctcccaggacatcggcctcgcatccttgggggtgtcggac
gaggaaattgagaagctgtccacgctgtactggttcaccgtggagttcggactgtgcaag
cagaacggccaggtgaaggcctacggcgcggggctgctgtcctcctatggggagctcctg
cactccctgtcggaggagcccgaggtccgggccttcgaccccgacgcagccgccgtctgc
cccagctcctccccgtctccccagtgcctccgagtccccactgggtgacagggggtctgt
gctgcccccccaaccaggagctacgcctcccgcatccaacgccccttctctgtgaagttc
gacccatacacgctggccatcgatgtgctggacagtccccacgccatccggcgctccctg
gagggcatccaggacgagctgcacaccctggcccacgcgctgaatgccatcagctag
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