Vicugna pacos (alpaca): 102544996
Help
Entry
102544996 CDS
T08098
Symbol
MAP3K5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5 isoform X1
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
vpc
Vicugna pacos (alpaca)
Pathway
vpc01524
Platinum drug resistance
vpc04010
MAPK signaling pathway
vpc04071
Sphingolipid signaling pathway
vpc04141
Protein processing in endoplasmic reticulum
vpc04210
Apoptosis
vpc04530
Tight junction
vpc04668
TNF signaling pathway
vpc04714
Thermogenesis
vpc04722
Neurotrophin signaling pathway
vpc04932
Non-alcoholic fatty liver disease
vpc04936
Alcoholic liver disease
vpc05010
Alzheimer disease
vpc05012
Parkinson disease
vpc05014
Amyotrophic lateral sclerosis
vpc05016
Huntington disease
vpc05017
Spinocerebellar ataxia
vpc05022
Pathways of neurodegeneration - multiple diseases
vpc05208
Chemical carcinogenesis - reactive oxygen species
vpc05417
Lipid and atherosclerosis
vpc05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
vpc00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
102544996 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102544996 (MAP3K5)
04668 TNF signaling pathway
102544996 (MAP3K5)
04071 Sphingolipid signaling pathway
102544996 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
102544996 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
102544996 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
102544996 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
102544996 (MAP3K5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
102544996 (MAP3K5)
09164 Neurodegenerative disease
05010 Alzheimer disease
102544996 (MAP3K5)
05012 Parkinson disease
102544996 (MAP3K5)
05014 Amyotrophic lateral sclerosis
102544996 (MAP3K5)
05016 Huntington disease
102544996 (MAP3K5)
05017 Spinocerebellar ataxia
102544996 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
102544996 (MAP3K5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102544996 (MAP3K5)
05418 Fluid shear stress and atherosclerosis
102544996 (MAP3K5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
102544996 (MAP3K5)
04932 Non-alcoholic fatty liver disease
102544996 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
102544996 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
vpc01001
]
102544996 (MAP3K5)
Enzymes [BR:
vpc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
102544996 (MAP3K5)
Protein kinases [BR:
vpc01001
]
Serine/threonine kinases: STE group
STE11 family
102544996 (MAP3K5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
Kinase-like
Pkinase_fungal
UPA
Motif
Other DBs
NCBI-GeneID:
102544996
NCBI-ProteinID:
XP_006200147
UniProt:
A0A6I9I2K8
LinkDB
All DBs
Position
8
AA seq
1364 aa
AA seq
DB search
MSAEAGEGITFSVPPFAEGGSYRRGGAAAVAEGEENQLPPPPPGSFWNVESAAAPGTGSP
SATSGSSATRCRGNSGGGRRTTVAYVINEASQGQLVVAESEALQCLREACEAVGATLETL
HFGKLDFGETAVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTNSD
SLQSLKEIICQKNTMCTGNYTFVPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGPIC
LPLVDRFIQLLKVAQASSSQYFRESILSDIRKARNLYTGKELAAELARIRQRVDNIEVLT
ADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHCAFALNRRNLPGDRAK
ALDIMLPLVQSEGQVASDMYCLVGRIYKDMFLDSNFMDTESRDRGASWFKKAFESEPTLQ
SGINYAVLLLASGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLAND
HLRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTSEQPVAKQELVDFWMDFLVEAT
KTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASSVR
GVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGRATEEGDCESDS
LEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHK
HLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEG
LKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEI
IDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAE
AKAFILKCFEPDPDKRDCANDLLLDEFLKVSSKKKKTQPKLSALSAGSNEYLRSISLPVP
VLVEDTSSSSEYGSVSPDTELKVDPFSFKTRAKSCGERDVKGIRTLFLGIPDENFEDHSA
PPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMESLAQGAEEPKLKWEHITTL
VTSLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIKPH
WMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDAEDDHEEQPSNQTVQRP
HVVLEDAVATSGVSTLSSTVSHDSQNAHRSLNVQLGRMKIETNRLLEELVQKEKELQALL
HQAIEEKDQEIKHLKLKSQPIEIPGLPVCHLNSPGTNTEDSELTDWLRENGADEDTISRF
LAEDYSLVDVLYYVTRDDLKCLRLRGGMLCTLWKAITDFRDKQT
NT seq
4095 nt
NT seq
+upstream
nt +downstream
nt
atgagcgcggaggcgggcgagggcatcactttttccgtgccacccttcgccgagggcggc
agctaccggaggggaggagcggcagcggtggccgagggcgaggagaaccagctgccaccg
ccgccaccgggcagcttctggaacgtggagagtgccgccgcccctggcaccgggagtccc
agtgccacctcggggagcagcgccacccgatgccggggcaactctggtggcggccgacgg
accacagtggcatatgtcatcaacgaagcgagccaggggcagctggtggtggccgagagc
gaggccctgcagtgcctgcgggaggcgtgcgaggcggtgggcgccaccctggagaccttg
cattttggtaaactggactttggggaaaccgcggtgctggaccgtttttacaatgcagat
attgccgtggtggagatgagtgatgccttccggcagccatccttattttaccaccttgga
gtgagagaaagtttcagcatggccaacaacatcatcctctactgtgatactaattcagac
tctctgcagtcactgaaggaaatcatttgccagaagaatactatgtgcactgggaactac
acgtttgttccttacatgataactccgcataacaaggtctactgctgtgatagcagcttc
atgaagggtttgacggagctcatgcagccaaacttcgagctgcttcttggacccatctgc
ttacctcttgtggatcgtttcattcagcttttgaaggtggcacaagcaagttccagccag
tatttccgagaatctatactcagtgatatcaggaaagctcgtaacttatacactggtaaa
gagttggcagctgaattggcaaggattcgacagcgagtggataatattgaagtcttgaca
gcagatattgtcataaatctgttactttcctacagagatattcaggactatgattctatt
gtgaagctagtagagactttagaaaagctgccgacctttgatttggcctcccatcaccat
gtgaagtttcattgtgcatttgcactgaataggagaaatctccctggagatagagcaaaa
gctcttgacattatgcttcccctggtgcaaagtgaagggcaagtggcttcggatatgtat
tgcctcgttggtcgaatctacaaagatatgtttttggactctaacttcatggacactgaa
agcagagaccgtggagcatcttggttcaaaaaggcatttgaatctgagccaacactacag
tcaggaattaattatgcggtcctcctcctggcatctgggcaccagtttgaatcttccttt
gagcttcgaaaagttggcgtgaagctaagtagccttcttggtaaaaagggaaacttggaa
aaactccagagctactgggaagttggattttttctgggggcaagtgtcctggccaatgac
cacttgagagtcattcaagcatctgaaaagcttttcaaactgaagacaccagcatggtac
ctcaagtctattgtagagacaattttgatatataagcattttgtgaaactgacttcagaa
cagcctgtggccaaacaggaacttgtggacttctggatggatttcctggtcgaggccaca
aagacagatgtcactgtagttaggtttccagtattaattttagaaccaaccaaaatctat
caaccttcatatttgtctatcaacaatgaagttgaggaaaagacaatatctatttggcac
gtgcttcctgatgacaagaaaggtatacatgaatggaattttagtgcttcttctgtcaga
ggagtgagtatttctaaatttgaagaacgatgctgttttctttatgtgcttcacaattct
gatgatttccaaatctatttctgtacagaacttcattgtaaaaagtttttcgaaatggtg
aacaccattaccgaagagaaggggagagctacggaggaaggagattgtgaaagtgactcc
ctggagtatgactatgaatatgatgaaaatggtgacagagtcgttttaggaaaaggcact
tacgggatagtttatgctggtcgagatctgagcaaccaagtcagaatcgccattaaggag
atcccagagagagatagcagatactcccagcccctacatgaagaaatagcattgcacaag
catctcaagcacaaaaatattgtccagtatctgggctccttcagtgagaatggtttcatt
aaaatcttcatggagcaggtcccaggaggaagtctttctgctcttcttcggtccaaatgg
ggcccgctgaaggacaacgagcaaaccattggcttttatacaaagcagatactggaagga
ttaaaatacctccatgacaatcagatagttcaccgggatataaagggtgacaatgtgttg
attaatacctacagtggtgtcctcaagatctctgacttcgggacatcaaagagactcgct
ggcataaatccatgtactgaaacttttactggtacccttcagtatatggcaccagaaata
atagataaaggaccaagaggctacgggaaagcagcagacatttggtctttgggctgcacg
atcattgaaatggccactggaaaaccacccttttacgaactgggagaaccacaagcagct
atgttcaaggtgggaatgtttaaagttcaccccgagatcccagagtccatgtcagcagag
gccaaggcgttcatactgaaatgttttgaaccagaccctgacaagagagactgtgctaac
gacttgcttttggatgagttcttaaaagtttcaagcaaaaagaaaaagacacaaccgaag
ctttcagctctttcagctggatcaaatgagtatctcaggagtatctcgttgccggtccct
gtcctggtggaggacaccagcagcagcagtgagtacggctcagtttctccggacacggag
ttaaaggtggaccccttctctttcaaaacaagagccaagtcctgcggagaaagagatgtc
aaaggcataaggacgctctttctgggcatccccgatgaaaattttgaagatcacagtgca
ccaccgtctcctgaagaaaaagattccggattctttatgctgaggaaggacagtgagaga
cgggccacgcttcacaggatcctgacagaagaccaagacaaagttgtgagaaacttaatg
gaatctttggctcagggggctgaagaacccaaactgaaatgggagcacattacaaccctt
gtcacaagcctcagagaatttgtgaggtccactgaccgaaagatcatagccaccaccctg
tcaaagctgaagctggagctggacttcgacagccacggcattagtcaagtccaggtggtg
ctcttcggtttccaagatgctgtcaataaagttcttcggaaccataacatcaagccacac
tggatgtttgccttagacagtatcatccgaaaggcggtgcagacagccattaccattctg
gttccagaactgaggccacattttagccttgcatctgaaagtgatactgctgatcaagaa
gacttggatgcagaagatgaccatgaggaacagccttcgaatcaaactgtccaaagacct
cacgtggtccttgaagatgctgtggccacctcaggggtgagcacgctcagttctactgta
tcccatgactcccagaatgctcaccgatcactgaatgtacagcttggaaggatgaaaata
gaaacaaatagattattggaagaattggttcagaaagagaaagaattacaagcactcctt
catcaagctattgaagaaaaagaccaagaaattaaacacctgaagctcaagtcccaaccg
atagaaattcctggattgcctgtgtgccacctgaattctcctggcacaaataccgaagat
tctgaacttactgactggctgagagaaaacggagctgatgaagacactataagtcggttt
ttggctgaggattattcactagtggatgttctctactacgttacacgtgatgatttaaaa
tgcctgagactaaggggagggatgctgtgcacactgtggaaagccatcactgactttcga
gacaaacagacatga
DBGET
integrated database retrieval system
