Vulpes vulpes (red fox): 112911455 Help Entry 112911455         CDS       T05911                                  Symbol ADCY1 Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism vvp  Vulpes vulpes (red fox) Pathway vvp00230   Purine metabolism vvp01100   Metabolic pathways vvp01522   Endocrine resistance vvp04015   Rap1 signaling pathway vvp04020   Calcium signaling pathway vvp04022   cGMP-PKG signaling pathway vvp04024   cAMP signaling pathway vvp04062   Chemokine signaling pathway vvp04072   Phospholipase D signaling pathway vvp04114   Oocyte meiosis vvp04211   Longevity regulating pathway vvp04213   Longevity regulating pathway - multiple species vvp04261   Adrenergic signaling in cardiomyocytes vvp04270   Vascular smooth muscle contraction vvp04371   Apelin signaling pathway vvp04540   Gap junction vvp04611   Platelet activation vvp04713   Circadian entrainment vvp04714   Thermogenesis vvp04720   Long-term potentiation vvp04723   Retrograde endocannabinoid signaling vvp04724   Glutamatergic synapse vvp04725   Cholinergic synapse vvp04727   GABAergic synapse vvp04750   Inflammatory mediator regulation of TRP channels vvp04911   Insulin secretion vvp04912   GnRH signaling pathway vvp04913   Ovarian steroidogenesis vvp04914   Progesterone-mediated oocyte maturation vvp04915   Estrogen signaling pathway vvp04916   Melanogenesis vvp04918   Thyroid hormone synthesis vvp04921   Oxytocin signaling pathway vvp04923   Regulation of lipolysis in adipocytes vvp04925   Aldosterone synthesis and secretion vvp04926   Relaxin signaling pathway vvp04927   Cortisol synthesis and secretion vvp04928   Parathyroid hormone synthesis, secretion and action vvp04934   Cushing syndrome vvp04935   Growth hormone synthesis, secretion and action vvp04970   Salivary secretion vvp04971   Gastric acid secretion vvp04972   Pancreatic secretion vvp04976   Bile secretion vvp05032   Morphine addiction vvp05142   Chagas disease vvp05146   Amoebiasis vvp05163   Human cytomegalovirus infection vvp05166   Human T-cell leukemia virus 1 infection vvp05200   Pathways in cancer vvp05207   Chemical carcinogenesis - receptor activation vvp05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:vvp00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     112911455 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     112911455 (ADCY1)    04371 Apelin signaling pathway     112911455 (ADCY1)    04020 Calcium signaling pathway     112911455 (ADCY1)    04072 Phospholipase D signaling pathway     112911455 (ADCY1)    04024 cAMP signaling pathway     112911455 (ADCY1)    04022 cGMP-PKG signaling pathway     112911455 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     112911455 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     112911455 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     112911455 (ADCY1)    04062 Chemokine signaling pathway     112911455 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     112911455 (ADCY1)    04923 Regulation of lipolysis in adipocytes     112911455 (ADCY1)    04912 GnRH signaling pathway     112911455 (ADCY1)    04913 Ovarian steroidogenesis     112911455 (ADCY1)    04915 Estrogen signaling pathway     112911455 (ADCY1)    04914 Progesterone-mediated oocyte maturation     112911455 (ADCY1)    04921 Oxytocin signaling pathway     112911455 (ADCY1)    04926 Relaxin signaling pathway     112911455 (ADCY1)    04935 Growth hormone synthesis, secretion and action     112911455 (ADCY1)    04918 Thyroid hormone synthesis     112911455 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     112911455 (ADCY1)    04916 Melanogenesis     112911455 (ADCY1)    04925 Aldosterone synthesis and secretion     112911455 (ADCY1)    04927 Cortisol synthesis and secretion     112911455 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     112911455 (ADCY1)    04270 Vascular smooth muscle contraction     112911455 (ADCY1)   09154 Digestive system    04970 Salivary secretion     112911455 (ADCY1)    04971 Gastric acid secretion     112911455 (ADCY1)    04972 Pancreatic secretion     112911455 (ADCY1)    04976 Bile secretion     112911455 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     112911455 (ADCY1)    04727 GABAergic synapse     112911455 (ADCY1)    04725 Cholinergic synapse     112911455 (ADCY1)    04720 Long-term potentiation     112911455 (ADCY1)    04723 Retrograde endocannabinoid signaling     112911455 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     112911455 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     112911455 (ADCY1)    04213 Longevity regulating pathway - multiple species     112911455 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     112911455 (ADCY1)    04714 Thermogenesis     112911455 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     112911455 (ADCY1)    05207 Chemical carcinogenesis - receptor activation     112911455 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     112911455 (ADCY1)    05163 Human cytomegalovirus infection     112911455 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     112911455 (ADCY1)    05142 Chagas disease     112911455 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     112911455 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     112911455 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     112911455 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     112911455 (ADCY1) Enzymes [BR:vvp01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      112911455 (ADCY1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom DUF6688 Motif Other DBs NCBI-GeneID:  112911455 NCBI-ProteinID:  XP_025843795 UniProt:  A0A3Q7SNX8 LinkDB All DBs Position Unknown AA seq 1434 aa AA seqDB search MYGVFVRVLAERSQRKAFLQARSYIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLK PPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATVSAAP DVRVSLEQPRGLRGCRCDLADAECVGPAQLSSPTASASPPATPLCKRGCLAERTQGAPSW PQTEGGGWVGRPRPEGHLSRLVAFDDAEPPCCGRRLLAFGPRFTRVWILTSHSSLMIRFH FGLFFLFFRSGCTASSRRLCFHLWNFSMNPPHTPAALSRSLPAAEDDDPLSLSAPRVLDV TAPCAHSLGPSPSLEDDEAAAMPLSPAQWTASVEALGLSGPRHLLVMSGVPSLAALFQAG YVSGFNIRWALADGTELVPLVTAPQTLKRAGQGMRGAEGAGQRGGAFSWFPQRKGEAGEG PDSRLWGLPAGASRLQGRGRPQPVSPDGEMPPHPAPHTDAAIASVLGKWFSSSSSGVSGR RGADVHDDRLLPRATPGAGPSRASLGLRSRRWADGLSAAGQTWLLCGSCPSGGQRLWDHR TLILPRGRLARAGGLAPAPGLPLRGLRLEHGQVGAAPPLSRELAHGSRDLEVRRRAGQPG GVEADSGTFTKDTSAADSLPGDGTLGEGSLSLACVSVLACLPTGDDGDGYRASGRTATSK RVPLWCQGDISRTRFAPALVFGVTSPSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYD VWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSFLKAHNIETFFIV PSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRR ALRTASEKLRNRSSFSANVVYTTPGTRVNRYIGRLLEARQMELEMADLDFFTLKYKQAER ERKYHQLQDEYFISAVVLALILTALFGLVYLLIIPQXVVVLLLLVFCICFLVACVLYLHI TRVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWAWSSSPNRTLVVLTPGGQSA LLPAAPCESAPHALLCGLVGTLPLAIFLRVSSLPKMIXTPGPWGRCAAARLPGHTRQALG GAVSGRSFEPIMAILLFSCTLALHARQVDVKLRLDYLWTAQAEEERDDMERVKLDNKRIL FNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFDDFYIELDGNNMGVECLRLL NEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTTGTKAKKCISSHLSTLADFAIE MFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGR IQVTEEVHRLLRRGTYRFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQARSLGAERKMCAY GRAGLQARLATGPPPVAPMAGLPVQAGLGALQGSGLPPCPHGQHLPPRAAGKEA NT seq 4305 nt NT seq  +upstreamnt  +downstreamnt atgtacggggtgttcgtgagggtcctggccgagcgctcccaaaggaaagccttcctgcag gcccgcagctacattgaagaccggctgaggctggaggacgagaacgagaagcaggagcgg ctgcttatgagccttctgccccggaatgttgccatggagatgaaggaggacttcctgaag ccccccgaaaggattttccacaagatttacatccagcggcatgacaatgtgagcatcctc ttcgcggacatcgtgggcttcacgggcttggcgtcacagtgcaccgcgcaggagttggtc aagctcctcaacgagctcttcggcaagtttgatgaactggccacggtaagcgcagccccc gatgttcgcgtgtcactggagcagcctcgggggctccggggttgcaggtgcgacctcgcg gatgccgaatgcgtcggtcccgcccagctgtcgtcacccacagcttctgcatcaccgccc gcgactcctttgtgcaaaagagggtgcttggccgagcgcacccagggcgccccgagctgg ccccagaccgagggtggtggctgggtggggaggccccgccctgaaggtcacctcagccgg ttggtggcgtttgacgatgccgagcccccttgctgtggcaggagactgctggcgtttgga ccccggtttacccgtgtgtggatcttgacgtcccacagctcactgatgatccgttttcat tttggcctcttcttccttttctttcgttccggatgcaccgcgtcgtctcggagattatgt ttccatctgtggaacttcagcatgaaccccccacacacgccagccgccctgtcgaggtcg ctgccggcagctgaggatgacgaccctctgtccttgagtgctccgagggtgttggatgtc accgcaccttgtgctcacagcctgggccccagcccttccctcgaggatgacgaggccgcc gcgatgcctttgtcacccgcccagtggaccgccagcgtggaagctctgggtctctctggg ccgcggcacctgctcgtcatgtcaggtgttccctccttggcagccttgttccaggcggga tacgtgtctgggtttaatatacgttgggcgctggccgatggcacggagctcgtgccactg gtcacggccccgcagaccctgaagagggcagggcaaggcatgcggggcgcagagggggct ggacagcgtggtggggctttctcgtggtttccacagcggaagggcgaggcgggcgagggg cctgacagtcggctctggggcctccccgcgggcgcctcccgcctccagggacgaggccgc ccccagcccgtgtccccggacggcgagatgcccccccaccccgccccgcacacagatgcg gcaattgcttccgtcctcgggaagtggttttccagctcgtcctccggcgtctcaggacgc aggggagccgacgtgcacgatgaccgcctgctgcccagagccacaccgggcgcggggccg tctcgggccagcctgggcctgcggagtcggcgctgggctgacggcctctctgcggccgga cagacgtggctcctgtgtggctcctgcccctccggcgggcagaggctctgggaccacagg accctcatcctaccccggggccggctcgcaagggccgggggcctggctccagctcccggg ctgcccctcaggggcttgaggttggagcacggccaagtcggtgcagcacctcctctgtct cgcgagctggcgcacggcagccgggacttggaggttagaagacgagccgggcagccggga ggggtggaggctgacagcgggaccttcaccaaggacacatccgccgctgacagcctgcct ggggacgggacgttgggagagggctccctgtccttggcctgcgtgagcgtcctggcctgc ctgcccactggggacgatggggacggctacagagcgtcgggtcgcacagccaccagcaag cgggtgccgctgtggtgccaaggagacattagccggacacgctttgccccggctctggtg tttggggttacgtctccgtcggtggccgaggccactgaggtggacctgaacatgcgtgtg gggctgcacaccggcagggtcctctgcggggtcctcggcctgcgcaagtggcagtatgac gtgtggtccaacgacgtgaccctggccaacgtcatggaggccgctggcctgcccgggaag gtccacatcacgaaaacgacgctggcgtgtctgaacggtgactacgaggtggagccgggc cacgggcacgagaggaacagcttcctgaaagctcacaacatcgaaacgttcttcatcgtg ccgtctcaccggcggaagatattcccggggctcatcctgtccgacatcaagccagccaag aggatgaaattcaagaccgtgtgctacctgctggttcagctcatgcactgccggaagatg ttcaaggcggagatcccgttctccaacgtcatgacgtgtgaggatgacgacaagcggagg gcattgagaaccgcatcggagaaactcagaaaccgctcatcgttctctgcgaacgtcgtc tataccacgccaggcacgcgcgtcaacaggtacatcggccgcctcctggaagcgcgccag atggagctggagatggcagacctggacttcttcaccctgaagtacaagcaggctgagcgc gagcgcaagtaccaccagctccaggacgagtatttcatcagtgccgtggtgctggcgctc atcctcaccgccctgttcggcctcgtctaccttctcatcatcccgcagatngtggttgtc ctcttgctcctggtgttctgcatctgcttcctggtggcctgcgtcctgtacctgcacatc actcgggtccagtgttttcccggatgcctgaccatccagatccgcaccgtcttgtgtatt ttcatagtggtcttgatctactccgtggcccaaggatgtgtggtgggctgtctgccctgg gcctggagctccagccccaacaggaccctggtggtcctgacgcccggcggccagagcgca ctgctgcccgctgcgccctgcgagtctgcgccccacgccctgctctgcggcctggtgggc acgctgccactggccatcttcctgcgagtgtcctccctgcccaaaatgatccntacaccc gggccttggggtaggtgcgctgctgccaggctccctggacacacccgtcaggcgctgggc ggcgcggtgtccgggcgcagcttcgagcccatcatggccatcctgctgttctcgtgcacg ctggccctgcacgcccggcaggtggacgtcaagctgcggctggactacctctggacggca caggcagaggaagagagggatgacatggagagggtgaagctggacaacaagaggattctc ttcaacctcctgccggcccacgtcgctcagcacttcctcatgtccaacccccggaacatg gacctgtactaccagtcctactcgcaggtgggcgtcatgttcgcctccatccccaacttt gacgacttctacatcgagctggatggcaacaacatgggcgtggagtgtctgcgcctcctg aatgagatcatcgctgactttgacgagctcatggacaaagacttttacaaggacctggag aagatcaagaccatcgggagcacctacatggctgcggtggggctggcacccacgaccggg accaaggcaaagaagtgcatctcctcccacctgagcacgctggcggacttcgccattgag atgttcgacgtcctggacgaaatcaactaccagtcttacaacgacttcgtgctccgcgtc ggcatcaacgtgggccctgtggtggccggggtgatcggggcccgaaggccacagtacgac atctggggaaacacggtcaatgtggccagtcggatggacagcaccggcgttcagggcaga atccaggtgacggaggaggttcaccggctgctgcgaaggggcacataccgcttcgtgtgc cgcgggaaggtcagcgtgaaaggcaagggcgagatgcttacgtacttcctggaaggccgg actgatgggaacggctcccaggccaggtccttgggcgcagagcggaagatgtgcgcttac gggcgagccggcctccaggccagactggccacgggcccgcccccggtggcccccatggcc ggcctcccggtccaagctgggctgggggctctgcagggctcggggctccccccgtgcccc cacggccagcacctgccccccagagcagcggggaaggaggcttag

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