KEGG   Vulpes vulpes (red fox): 112919127
Entry
112919127         CDS       T05911                                 
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
  KO
K00161  pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
Organism
vvp  Vulpes vulpes (red fox)
Pathway
vvp00010  Glycolysis / Gluconeogenesis
vvp00020  Citrate cycle (TCA cycle)
vvp00620  Pyruvate metabolism
vvp00785  Lipoic acid metabolism
vvp01100  Metabolic pathways
vvp01200  Carbon metabolism
vvp01210  2-Oxocarboxylic acid metabolism
vvp04066  HIF-1 signaling pathway
vvp04922  Glucagon signaling pathway
vvp05230  Central carbon metabolism in cancer
vvp05415  Diabetic cardiomyopathy
Module
vvp_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:vvp00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    112919127 (PDHA1)
   00020 Citrate cycle (TCA cycle)
    112919127 (PDHA1)
   00620 Pyruvate metabolism
    112919127 (PDHA1)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    112919127 (PDHA1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    112919127 (PDHA1)
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    112919127 (PDHA1)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    112919127 (PDHA1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    112919127 (PDHA1)
Enzymes [BR:vvp01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.1  pyruvate dehydrogenase (acetyl-transferring)
     112919127 (PDHA1)
SSDB
Motif
Pfam: E1_dh DXP_synthase_N TPP_enzyme_C
Other DBs
NCBI-GeneID: 112919127
NCBI-ProteinID: XP_025853272
UniProt: A0A3Q7SUE7
LinkDB
Position
Unknown
AA seq 390 aa
MRKMLAAVSRVLSGVSQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLRYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDVLCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSIS
NT seq 1173 nt   +upstreamnt  +downstreamnt
atgaggaagatgctcgccgctgtctcccgcgtgttgtcgggcgtctcccagaagccggca
agcagagtgttggtggcctcccgtaattttgcaaatgatgctacatttgaaattaagaaa
tgcgatcttcaccggctagaagagggccctcctgtcaccacagtgctcaccagggaggat
gggctcaggtactataggatgatgcagacagttcgccgaatggagttaaaggcagatcag
ctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgt
tgtgtgggcctggaggctggcataaatcccacagaccatcttatcacagcctatcgggct
catggctttacctttactcgtggcctttctgtcagagaaattctcgcagagcttacagga
agaagaggaggttgtgctaaaggaaaaggtggatcgatgcatatgtatgccaagaacttc
tatgggggtaatggcattgttggagctcaggtgcccttgggagcaggaattgctttggcc
tgtaagtataatggaaaggatgaggtctgtttgactttatatggcgatggtgctgctaat
cagggtcagatatttgaagcttacaacatggcagctttgtggaaattgccgtgtatcttc
atctgtgagaataaccgctacggaatgggaacgtctgttgagagagcagcagccagcact
gattactacaagagaggcgacttcattcctgggctgcgggtagatggaatggatgtcttg
tgtgtccgggaggcaacaaggtttgcagccgcctactgtagatctggaaaggggcccata
ttgatggagctacagacttaccgttaccatggacacagcatgagcgaccctggtgtcagt
taccgtacacgagaggagattcaggaagtaagaagtaagagtgaccctatcatgcttctc
aaggatagaatggtgaacagcaacctggccagtgtcgaggaactaaaggaaattgatgtt
gaagtgaggaaggaaattgaggatgctgcccagtttgccactgctgatccggaaccgcct
ttggaagaactaggctatcacatttacagcagcgatccgccttttgaagttcggggtgca
aatcagtggatcaagtttaagtctatcagttaa

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