Xenorhabdus doucetiae: XDD1_0203
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Entry
XDD1_0203 CDS
T03784
Symbol
metL
Name
(GenBank) Bifunctional aspartokinase/homoserine dehydrogenase 2 [Includes: Aspartokinase; Homoserine dehydrogenase]
KO
K12525
bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:
2.7.2.4
1.1.1.3
]
Organism
xdo
Xenorhabdus doucetiae
Pathway
xdo00260
Glycine, serine and threonine metabolism
xdo00261
Monobactam biosynthesis
xdo00270
Cysteine and methionine metabolism
xdo00300
Lysine biosynthesis
xdo01100
Metabolic pathways
xdo01110
Biosynthesis of secondary metabolites
xdo01120
Microbial metabolism in diverse environments
xdo01230
Biosynthesis of amino acids
Module
xdo_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
xdo_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
xdo_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
xdo00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
XDD1_0203 (metL)
00270 Cysteine and methionine metabolism
XDD1_0203 (metL)
00300 Lysine biosynthesis
XDD1_0203 (metL)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
XDD1_0203 (metL)
Enzymes [BR:
xdo01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
XDD1_0203 (metL)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
XDD1_0203 (metL)
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Gene cluster
GFIT
Motif
Pfam:
AA_kinase
Homoserine_dh
NAD_binding_3
Motif
Other DBs
NCBI-ProteinID:
CDG15914
UniProt:
A0A068QMM6
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All DBs
Position
208440..210875
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AA seq
811 aa
AA seq
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MSTLATAGAESGRQLHKFGGSSLADVKCYQRVADIMANYSQPGDLMVVSAAGSTTNQLID
WLKLSQSDRISAHQIQQSLRRYQQELIRGLLPEAVAEELSAMFIADLERLSALLDKPVTD
ITYAEVVGHGEIWSARLMAAVLEDQGIPSAWLDARQFLRAERVAQPQVDISLSQPLFSQL
LIQNPNKRLVVTGFISRNQKGETVLLGRNGSDYSATQVGALAGAKKVTIWSDVAGVYSAD
PRKVKDACLLPLLRLDEASELARLAAPVLHTRTLQPVSISDIDLQLRCSYQPEQGSTRIE
RVLATGTGAKIVTSHDDVCLIELHVSSAHDFRQIYKDIDALLKRAQVRPLATGLHADCNL
IQLCYTSEVVNSALDVLQDAALPGKLSLREGLALVALVGAGVCKNPLHSHRFYQQLKDQP
VEFIWHAEDGISLVAVLRSNQTSHLIQGLHQSLFRAEKRIGLVLFGKGNIGSRWLELFAR
EQKNISARSDFEFILAGVVDSRRSLLNYQGIDASRALAFFDDEATEHEEDALFLWMRAHP
YDDLVVLDVTASEELAKEYIYFASYGFHVISANKVAGSSASNTYRLIRDAFAKTGRHWLY
NATVGAGLPINYSVRDLRESGDTILSISGVFSGTLSWLFLQFDGSVPFSELVEQAWQQGL
TEPDPRIDLSGQDVMRKLVILAREAGYEIEPDHVRVESLVPEEARGGSLEEFFENSAAIN
EQMLQRLEAAREMGMVLRYVARFDASGKAKVGVEAVRSDHPLASLLPADNVFAIESRWYR
DNPLVIRGPGAGRDVTAGAIQSDLNRLSQLL
NT seq
2436 nt
NT seq
+upstream
nt +downstream
nt
atgagtacactggcaacagcgggggcggaatctggccgccagttacataaatttggcggc
agcagcctggcggatgtgaagtgctatcagcgggtagctgacattatggcgaactacagc
cagccgggtgatttgatggtggtatcggcagcagggagtaccaccaaccagttgatcgac
tggcttaaattgagccagagtgaccggatctccgcccatcaaatccagcaatctttgcgg
cgttaccagcaagaattaatccgtggtttgttgcccgaagccgttgcagaagagctgagt
gccatgtttatcgctgatctggaaagattaagtgccttgttggataaacccgtcaccgat
attacttatgcggaagtggtcggtcatggagaaatctggtctgcgcgcttaatggcggcg
gtacttgaggatcaggggatacccagcgcatggctggatgcgcgtcaattcctgcgggca
gagcgcgttgcacagccgcaggttgatatcagtttatcccagcccctgtttagccaatta
ttgatccaaaatcccaataagcgtttagtggtgaccggttttatttccagaaatcagaag
ggggaaacggtattactggggcgcaatggcagcgactattcggcgacccaagtcggggcg
ttggcgggcgccaaaaaagtcacgatttggagtgatgtggctggggtttacagtgccgat
ccgcgtaaagtcaaagatgcctgcctgttgccgttgttgcgtttggatgaagccagtgaa
ttggcgcgtctggcggcaccggtgctgcatacccggacattgcagccggtttccatcagc
gatattgatctgcaattgcgttgcagttatcagcctgaacagggttccacccggattgaa
cgggtgctggcaacggggactggggccaaaatcgtgaccagccatgatgatgtttgcctg
attgaactgcatgtttcttctgcccatgatttcaggcaaatctacaaagacattgacgcg
ttgttaaagcgcgctcaagtccggccactggcaaccggattacatgcagactgcaacctg
atccaactttgttacacctcagaggttgtcaatagcgcccttgatgttttgcaggatgcc
gccttacccggcaaactctctttgcgtgaaggcttggcgctggtggcgttggtcggggcg
ggggtatgcaaaaatccgctgcacagccatcgtttttaccaacaattaaaagatcagccc
gttgaatttatctggcacgcggaagatggcatcagtcttgtggcggtactgcgttccaat
cagacgtcgcatttgattcagggattacaccaaagcctgtttcgggcagaaaaacgcatc
ggtttggtgctgtttggcaaaggaaatattggttctcgttggttagaactgtttgcccgc
gaacaaaagaatatttctgcccgcagcgattttgaatttattttggcgggtgtcgtcgat
agccgccggagtttgctgaattatcagggcattgatgccagccgggcactggccttcttt
gatgatgaagcgactgaacatgaagaagatgcgctgtttttatggatgcgggcgcatcct
tatgacgatttggtggttctggacgtgacggcaagtgaagaattagccaaagagtatatc
tattttgccagttatggatttcacgtcatcagtgccaacaaagttgccggctcttccgcc
agcaacacctaccgcctgatccgcgatgcctttgcaaaaacggggcgccattggttatac
aacgccacggtgggtgccggattgccgattaactactccgtcagggatctgcgggaaagc
ggcgatacgattttgtctatcagcggcgttttctccggcacattatcctggctgttcttg
caatttgatggttcggtgcctttcagtgaattagttgaacaggcatggcaacaggggttg
acggaacccgatccacgtatcgatctctctggtcaggatgtgatgcgtaagctggtgatc
ctggctcgcgaagccggttatgagatagagcctgatcacgtgcgggttgagtcgctggtg
ccggaagaagcacgaggcggctctctcgaagagttctttgaaaacagtgccgccattaat
gagcagatgctgcaacgtctggaagcggcacgggaaatgggcatggtactccgctatgtc
gcacgttttgatgccagtggtaaagccaaagtgggcgtggaagcggtgcgcagtgatcac
ccattggcctcactgctgccggccgataatgtctttgcgatagaaagccgctggtatcgc
gataatccgctggtgatccgcggccccggtgcgggacgggatgtcacggcgggcgcaatt
caatccgatttaaaccgcctgtcgcaacttttgtag
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