Xenopus laevis (African clawed frog): 379494
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Entry
379494 CDS
T01010
Symbol
hsd11b1l.2.L, 11-DH3-B, hsd11b1l-b, hsd11b1l.2, hsd3-B
Name
(RefSeq) hydroxysteroid 11-beta-dehydrogenase 1-like protein B precursor
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
xla
Xenopus laevis (African clawed frog)
Pathway
xla00140
Steroid hormone biosynthesis
xla00980
Metabolism of xenobiotics by cytochrome P450
xla01100
Metabolic pathways
Module
xla_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
xla00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
379494 (hsd11b1l.2.L)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
379494 (hsd11b1l.2.L)
Enzymes [BR:
xla01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
379494 (hsd11b1l.2.L)
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GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
DUF726
THF_DHG_CYH_C
DUF1776
Eno-Rase_NADH_b
Motif
Other DBs
NCBI-GeneID:
379494
NCBI-ProteinID:
NP_001079804
Xenbase:
XB-GENE-5834075
UniProt:
Q7SYS6
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Position
1L:164348465..164355605
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AA seq
291 aa
AA seq
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MAGVILLLLSLCVGYIAYYFFRTESMNKESVRGKRVLITGSSTGLGEQIAYEFARMGAHI
MITARRLQQLQEVASQCMKLGAASAHYVASDMGNLESAQSVAQEAVVKLGGLDYLVLNHI
GGSGGFGFFKGDMDPVVGSTTVNFLSYVQLTSSALSALQESQGSIVVISSMSGRIGAPFT
TSYCASKFALEGFYSSLRREFALQNSKMSVTVAVLGYIDTENAVKKVGNKVSMTASSKED
CAREVVKAAVLQQPEIFYPYWGIKPFVLLRDWFPGLVAKILDKCYILENIQ
NT seq
876 nt
NT seq
+upstream
nt +downstream
nt
atggctggggtaatattactgcttctgtctctgtgtgttgggtacattgcttattacttc
tttcgcactgagtccatgaacaaagaatcagttcgtgggaagcgtgtactaataacagga
tccagcactggccttggagagcagatcgcttatgaatttgctcggatgggggcacatata
atgatcacagctagaagacttcagcagttgcaagaagtggcaagccaatgtatgaagtta
ggagctgcctctgcacactatgtggcctctgatatgggaaacttggaatcagcacagtct
gtggcccaagaagcagtggtcaagcttggaggcttggattacttggttctgaatcacatt
ggtggatctggaggatttggatttttcaaaggtgacatggatccagttgtaggatctact
actgtgaacttccttagctatgtccagcttacttcttctgcactgagcgccctgcaggaa
tcacaaggaagcattgttgtcatatcctcaatgagtggtcgcattggggctcctttcact
accagctattgtgcatccaaatttgccctggaagggttctacagctctctccgcagagaa
tttgctcttcagaatagcaaaatgtctgtgactgtggctgttcttggatacattgataca
gaaaatgcagtaaagaaggttggaaataaagtgtccatgacagcttcatcaaaagaagac
tgtgcacgtgaagtggtcaaagcagctgtcctacaacaaccggaaattttttatccttac
tggggcattaagccattcgttttactgagagactggtttccgggcttggtggcaaaaata
cttgataaatgctacatcttagaaaacatccaatga
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