Xenopus laevis (African clawed frog): 387560 Help Entry 387560            CDS       T01010                                  Symbol tph1.L, tph, tph1, tph1.S Name (RefSeq) tryptophan 5-hydroxylase   KO K00502   tryptophan 5-monooxygenase [EC:1.14.16.4] Organism xla  Xenopus laevis (African clawed frog) Pathway xla00380   Tryptophan metabolism xla00790   Folate biosynthesis xla01100   Metabolic pathways Module xla_M00037   Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin Brite KEGG Orthology (KO) [BR:xla00001]  09100 Metabolism   09105 Amino acid metabolism    00380 Tryptophan metabolism     387560 (tph1.L)   09108 Metabolism of cofactors and vitamins    00790 Folate biosynthesis     387560 (tph1.L) Enzymes [BR:xla01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor     1.14.16.4  tryptophan 5-monooxygenase      387560 (tph1.L) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Biopterin_H ACT TH_ACT DUF5370 zf-C2HE DUF262 Motif Other DBs NCBI-GeneID:  387560 NCBI-ProteinID:  NP_001080923 Xenbase:  XB-GENE-996927 UniProt:  Q92142 LinkDB All DBs Position 4L:complement(491782..500495) Genome browser AA seq 481 aa AA seqDB search MYSNRKECPRRVKSFDSVNSGLDENQINNEFNKSTYIKIEDNKEYSENVCERGKASVIFS LKNEIGGLVKALKLFQEKHVNLIHIESRKSKRRNSEFEIFVDCDSNREQLNEIFQLLKPH VNVISMSPPENFTVQEDDMESVPWFPKKISDLDKCANRVLMYGSDLDADHPGFKDNVYRK RRKYFADVAMSYKYGDPIPHIEFTEEEIQTWGTVFRELNKLYPTHACREYLKNLPLLSKH CGYREDNIPQLEDVSRFLRERTGFTIRPVAGYLSPRDFLAGLAFRVFHCTQYVRHDSDPL NTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASDEAVQKLATCYFFTVEFGLCKQ EGKLKVYGAGLLSSISELKHSLSGNAKVKPFDPMVTCNQECIITSFQELYFVSESFEEAK EKMREFAKTIQRPFGLKYNPFTQSVDILKDTKSIAMVVRELRHELDIVNDALNKMNKQLG V NT seq 1446 nt NT seq  +upstreamnt  +downstreamnt atgtattccaaccgcaaggagtgcccccgcagggtcaagtcctttgattcagtcaactct ggattggatgagaatcagatcaataatgagttcaataaatcaacttacatcaagatcgaa gacaataaagaatacagtgagaatgtgtgcgagagagggaaggcctcagtcatcttctcc ctaaagaatgagattggggggctggtcaaagcactgaagcttttccaggagaaacacgtc aatctcattcatattgagtcccgaaagtcaaagagaagaaactctgagtttgagatcttt gtggattgtgacagcaacagggaacaactgaatgaaatcttccagctgctcaagcctcac gtcaatgtgatatccatgagcccccctgagaacttcactgtgcaggaggacgatatggaa agtgtcccctggttccccaagaagatctctgacctggacaaatgcgcaaacagagttcta atgtacggatcagatctggacgccgaccaccctggtttcaaggacaatgtgtaccgtaag agacgcaagtattttgccgacgttgcaatgtcctacaaatatggggatccaataccccac attgagtttacagaagaggagatacagacctgggggacagttttccgggagctcaataag ctgtacccaacacacgcctgccgagagtacctaaagaacctgccactcttgtccaaacac tgcgggtacagagaagataatatcccccaactggaagatgtgtctcgatttctccgagag cgcacaggattcaccattcgtcccgtcgctggatatttgtctcccagagatttccttgca ggactggccttccgggtttttcactgcacccaatatgtgaggcacgactccgacccactt aatacccctgagccggacacttgccatgaacttctgggacatgttcctcttcttgccgaa cccagttttgcccagttctcccaagaaattggcttggcctccttgggggcatccgatgaa gctgtacaaaaactggctacctgctacttcttcacagttgagtttggattgtgcaaacaa gaaggaaaactgaaggtatatggggccggactgctttcttctatcagtgagctgaagcac tctctctctggaaatgccaaagtgaagccttttgaccccatggtaacctgcaaccaggag tgcatcatcacttcattccaggagctttactttgtctcggagagttttgaagaagccaaa gagaagatgagagaatttgctaaaaccattcaacgcccctttgggctgaagtacaatccc tttacccagagcgtggatatcctaaaggatacaaagagcatcgccatggtggtcagagag ttgcgtcatgaactggacattgtcaacgatgcacttaacaagatgaacaagcagcttggg gtttaa

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