Xenopus laevis (African clawed frog): 446473
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Entry
446473 CDS
T01010
Symbol
pdha1.L, pdha, pdha1, pdha1-a, pdha1-b, pdhce1a, phe1a
Name
(RefSeq) pyruvate dehydrogenase E1 alpha 1 subunit L homeolog
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
xla
Xenopus laevis (African clawed frog)
Pathway
xla00010
Glycolysis / Gluconeogenesis
xla00020
Citrate cycle (TCA cycle)
xla00620
Pyruvate metabolism
xla00785
Lipoic acid metabolism
xla01100
Metabolic pathways
xla01200
Carbon metabolism
xla01210
2-Oxocarboxylic acid metabolism
Module
xla_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
xla00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
446473 (pdha1.L)
00020 Citrate cycle (TCA cycle)
446473 (pdha1.L)
00620 Pyruvate metabolism
446473 (pdha1.L)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
446473 (pdha1.L)
Enzymes [BR:
xla01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
446473 (pdha1.L)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
446473
NCBI-ProteinID:
NP_001086638
Xenbase:
XB-GENE-952676
UniProt:
Q6DEB0
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Position
2L:43742588..43754545
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AA seq
400 aa
AA seq
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MQKMLSLLSRVLKGKAQKPVTGAANEAVRVMVASRNYADFASEATFDVKKCDVHRLEEGP
PTQAVLTREQGLQYYRTMQTIRRMELKSDQLYKQKIIRGFCHLYDGQEACCVGLESGINP
TDHLITAYRAHGYTYTRGVSVKEILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQ
VPLGAGVALACKFFGKDEICVSLYGDGAANQGQIFETYNMAALWKLPCIFICENNRYGMG
TSVERAAASTDYYKRGDYIPGLRVDGMDVLCVREATKFAADHCRSGKGPILMELQTYRYH
GHSMSDPGVSYRTREEIQEVRSKSDPITLLKDRMLNNNLSSVEELKEIDVEVRKEIEEAA
QFATTDPEPPLEEIANHIYHNEPTFDVRGANLWIKYKSAS
NT seq
1203 nt
NT seq
+upstream
nt +downstream
nt
atgcaaaagatgttgtctctcctgtcccgtgtgctgaagggcaaagcccagaaacctgtc
actggggctgctaatgaggctgttcgtgtaatggtggcgtcccgtaactatgcagacttt
gcatcagaagctacgtttgacgttaagaaatgtgacgttcatcgtttggaagagggacct
cccacccaggccgttctaactcgagaacaggggctccaatattacaggactatgcagaca
atccgacgcatggagctgaaatcagatcaactgtacaagcaaaagatcatccgaggattc
tgccacctttatgatggacaggaagcatgctgcgtaggtctcgagtccggtatcaatccc
acagatcacttaattactgcgtatcgtgcacatggttatacctacacacgaggagtgtct
gtgaaggaaatcctagctgagctgacgggaagaaaaggtggctgtgccaaaggaaaggga
ggctccatgcatatgtatgctaagaacttctatggtgggaatggaattgtgggagctcag
gttccccttggagcaggtgttgctttggcttgtaagtttttcggaaaagatgagatctgt
gtgtccttgtatggtgatggtgctgctaatcagggacagatatttgaaacctataatatg
gccgctctgtggaagctgccctgtatctttatttgtgagaataacagatacggcatgggg
acatctgtggagagagcagcagccagtacagactattacaaacgaggagattacatccca
ggccttagagttgatggtatggatgttctgtgtgttcgagaagccactaagtttgcagct
gatcactgcagatctggaaagggtcctattttaatggaacttcaaacttaccgttaccat
ggacacagcatgagcgatcctggtgtaagttaccgtacaagagaagaaattcaggaagtg
agaagtaaaagtgatccgatcacccttcttaaggacagaatgttaaacaacaacctgtct
agtgtggaggaattaaaggaaattgatgtggaagtgaggaaagagattgaggaagctgct
cagtttgctaccactgaccccgaacctccactagaagaaattgcaaatcacatttatcac
aatgagcccacctttgatgtcagaggagcaaatctctggatcaaatacaaatcagctagt
taa
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