Xenopus laevis (African clawed frog): 447434
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Entry
447434 CDS
T01010
Symbol
pdha1.S, pdha, pdha1-a, pdha1-b, pdhce1a, phe1a
Name
(RefSeq) pyruvate dehydrogenase E1 alpha 1 subunit S homeolog
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
xla
Xenopus laevis (African clawed frog)
Pathway
xla00010
Glycolysis / Gluconeogenesis
xla00020
Citrate cycle (TCA cycle)
xla00620
Pyruvate metabolism
xla00785
Lipoic acid metabolism
xla01100
Metabolic pathways
xla01200
Carbon metabolism
xla01210
2-Oxocarboxylic acid metabolism
Module
xla_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
xla00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
447434 (pdha1.S)
00020 Citrate cycle (TCA cycle)
447434 (pdha1.S)
00620 Pyruvate metabolism
447434 (pdha1.S)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
447434 (pdha1.S)
Enzymes [BR:
xla01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
447434 (pdha1.S)
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GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
447434
NCBI-ProteinID:
NP_001087610
Xenbase:
XB-GENE-6253873
UniProt:
Q66JA7
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Position
2S:34025269..34055006
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AA seq
400 aa
AA seq
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MQKMLSLLSRVLKGPAQKPVTGAANEAVRVMMASRNYADFASEATFDIKKCDIHRLEEEP
PTQAVLTREEGLQYYRTMQTIRRMELKSDQLYKQKIIRGFCHLYDGQEACCVGLESGINP
TDHLITAYRAHGYTYTRGVSVKEILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQ
VPLGAGVALACKFFGKNEICVSLYGDGAANQGQIFETYNMAALWKLPCIFICENNRYGMG
TSVERAAASTDYYKRGDYIPGLRVDGMDVLCVREATKFAADHRRSGKGPILMELQTYRYH
GHSMSDPGVSYRTREEIQEVRSKSDPITLLKDRMLNNNLSNVEELKEIDVEVRKEIEEAA
QFATTDPEPPLEEIANHIYRNDPTFDVRGANLWIKYKSAS
NT seq
1203 nt
NT seq
+upstream
nt +downstream
nt
atgcagaagatgctgtctctgctgtcccgtgtgctgaagggcccagcccagaagcctgtc
actggggctgctaacgaggctgttcgtgtaatgatggcgtcccgtaactatgcagatttt
gcatcagaagctacgtttgacattaagaaatgtgacattcatcgtttggaagaggaacct
cccactcaggctgttctaactcgagaagaggggctccagtattacagaactatgcagaca
atccgacgcatggagctgaaatcagatcaactgtacaagcaaaagatcatcagaggattc
tgccacctctatgatgggcaggaggcatgctgtgtgggtctggagtctggtatcaatccc
acggatcacttaattactgcctatcgagcacatggctatacctacacacgaggagtgtct
gtgaaggaaattttagctgagctgactggaagaagaggtggatgtgccaaaggaaaggga
ggctccatgcatatgtatgctaagaacttctatggtgggaatggaattgtgggagctcag
gttccccttggagcgggtgttgctctggcttgtaagttttttggaaaaaatgagatctgt
gtgtccttgtacggtgatggggctgctaaccagggacagatatttgaaacctacaatatg
gctgccttatggaagctgccctgtatctttatttgtgaaaataacagatacggcatgggg
acctctgtggagagagcagcagcaagcacagactattacaaacgaggagactacatccca
ggtcttcgagttgatggtatggatgttctgtgtgttcgagaagccactaaatttgcagct
gatcaccgcagatctggaaagggtccaattttaatggagcttcagacttaccgttatcat
ggacacagcatgagcgatcctggtgtaagttatcgtaccagagaagaaattcaggaagta
agaagtaaaagtgatccgatcacccttctcaaggacagaatgttaaacaacaacctgtct
aatgtggaggaattaaaggaaattgatgtggaagtacggaaagagattgaagaagctgct
cagtttgctaccaccgaccctgaacctccactagaagaaattgccaatcacatttatcgc
aatgatcccacgtttgatgtcagaggagcaaatctctggatcaaatacaaatccgccagc
taa
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