Xenopus tropicalis (tropical clawed frog): 779627
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Entry
779627 CDS
T01011
Symbol
akr1c3
Name
(RefSeq) aldo-keto reductase family 1, member C3
KO
K04119
aldo-keto reductase family 1 member C3 [EC:
1.1.1.51
1.1.1.188
1.1.1.213
1.1.1.357
]
Organism
xtr
Xenopus tropicalis (tropical clawed frog)
Pathway
xtr00140
Steroid hormone biosynthesis
xtr00590
Arachidonic acid metabolism
xtr00790
Folate biosynthesis
xtr01100
Metabolic pathways
Module
xtr_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
xtr_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
xtr00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
779627 (akr1c3)
00590 Arachidonic acid metabolism
779627 (akr1c3)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
779627 (akr1c3)
Enzymes [BR:
xtr01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
779627 (akr1c3)
1.1.1.188 prostaglandin-F synthase
779627 (akr1c3)
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
779627 (akr1c3)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
779627 (akr1c3)
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Motif
Pfam:
Aldo_ket_red
Motif
Other DBs
NCBI-GeneID:
779627
NCBI-ProteinID:
NP_001072181
Xenbase:
XB-GENE-5821909
UniProt:
Q0VGY1
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Position
3:7604973..7612961
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AA seq
324 aa
AA seq
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MALHKDSYVELNDGHKMPVIGFGTYAPPKFPKSLAEEGTKVAIDVGYRHIDCAFLYGNEE
EVGRAIRAKIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMP
MEFKPGDDLFPADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNM
PGLKYKPVCNQVECHVYLNQSKLLEFCKSKDIVLVGYSVLGSSRDERWIEASTPVLLEDP
ALTEIAKKHNRTPAQVAMRYHLQRGVVVLAKSFTPARIQQNFQVFDFQLDAEDMRSIDGL
NRNMRYIDTSRWSDHPKYPYSEEY
NT seq
975 nt
NT seq
+upstream
nt +downstream
nt
atggcactgcacaaagactcctacgttgagctgaatgatgggcacaaaatgccagtgatt
ggatttggcacctacgcccctccaaagttccccaagagtttggcagaggagggcaccaaa
gtggccattgacgttggataccgccatattgactgcgcttttctctatgggaatgaggag
gaggttggacgggcgatcagggcaaagattgcggatggtaccgtgaagagggaggacgtg
ttctacactgggaagctctggtccacgtcccatacccccgagagggtccggccagccctg
gagaaatccctgaaagaccttcagttggattacatggatctgttcatcatccatatgccc
atggagttcaagcctggagatgatctctttccggcggatgaaaatgggaaatttatttac
cataacacggaccttagagatacatggaaggctctggaaaagtgcaaagacgcagggctg
gtcagatccatcggggtgtccaattttaaccacaagcagctggagctgatcctcaatatg
cctgggctgaaatataaacccgtctgtaaccaggtggaatgccacgtctacctgaatcag
agcaaactgctggagttctgcaagtccaaggacatcgtgttggtgggatacagcgtattg
gggtccagcagggatgagcgatggatagaagcgagcactcctgtgctcctggaagaccct
gcgctcactgagatcgctaagaagcacaaccggacccccgctcaggtagcaatgcggtac
cacctccagcgaggagtcgttgtccttgcaaagagcttcaccccagccaggatccagcag
aacttccaggtttttgactttcagctggacgcggaagacatgagaagcatcgatgggctg
aacagaaacatgcgttacatcgacacttccagatggtcggaccacccgaaatatccgtac
agtgaggaatactga
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