Yokenella regensburgei: HEC60_21250
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Entry
HEC60_21250 CDS
T06519
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
yre
Yokenella regensburgei
Pathway
yre00260
Glycine, serine and threonine metabolism
yre00261
Monobactam biosynthesis
yre00270
Cysteine and methionine metabolism
yre00300
Lysine biosynthesis
yre01100
Metabolic pathways
yre01110
Biosynthesis of secondary metabolites
yre01120
Microbial metabolism in diverse environments
yre01230
Biosynthesis of amino acids
Module
yre_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
yre_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
yre_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
yre00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
HEC60_21250 (thrA)
00270 Cysteine and methionine metabolism
HEC60_21250 (thrA)
00300 Lysine biosynthesis
HEC60_21250 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
HEC60_21250 (thrA)
Enzymes [BR:
yre01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
HEC60_21250 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
HEC60_21250 (thrA)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
NAD_binding_3
ACT_7
ACT
Sacchrp_dh_NADP
DUF6247
Motif
Other DBs
NCBI-ProteinID:
QIU91655
UniProt:
A0A6H0KE13
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All DBs
Position
4403662..4406124
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AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTIGGQDA
LPNISDAERIFAELLQGLADTQPAFPLEKLQATVEQEFAQIKHVLHGISLLGQCPDAVNA
ALICRGEKLSIAIMAGLLEARGHNVSVIDPVEKLLAVGHYLESTVDIAESTRRIVASQIP
ADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTGNPQAPGTLIGASSN
EDGLPVKGISNLNNMAMFNVSGPGMKGMVGMAARVFATMSRAGISVVLITQSSSEYSISF
CIAQADCARAKKAMEDEFYLELKEGLLEPLAIMERLAIISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVSNDDATTGVRVTHQMLFNTDQVIEVFVIGVGGVGGAL
LEQLKRQQSWLKNKHIDLRVCGVANSKAMLTHVHGLNLDNWQAELAEAKEPFNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSMDYYHELRQAAAGSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELQRFSGILSGSLSFIFGKLDEGMSLSEATILA
RGMGYTEPDPRDDLSGMDVARKLLILVRETGRELELHDIVVESVLPESFDATGDTESFMA
RLPELDAVFADRVAKARDEGKVLRYVGNIEDDGVCRVKIAEVDGNDPLYKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgagagtgttgaagttcggcggtacatcagtggcaaatgcagagcgctttctgcgggtt
gccgatattctggaaagcaacgccaggcaggggcaggtggcaaccgtgctgtctgctcct
gcgaaaattacgaaccatctggtggcgatgattgaaaaaaccatcgggggtcaggatgcg
cttcccaacatcagcgatgccgaacgtatttttgccgaactgcttcaggggctggcggac
acgcaacccgctttccctctggaaaagttacaggccaccgttgagcaagagtttgcgcag
atcaaacatgttctgcatggtattagcttgctcgggcagtgcccggacgcggtgaatgcg
gcgcttatctgccgtggcgaaaaactctcaatagccattatggcgggtctgctcgaagcg
cgcggtcacaacgtttcggtcatcgatccggtcgaaaaactgctggccgtggggcattac
ctcgaatctaccgtcgatatcgccgaatctactcgtcgtatcgtggcaagccagatcccg
gctgaccacatggtgttgatggcaggttttaccgcagggaacgagaagggcgagctggtg
gtgctggggcgtaatggctctgactattctgccgcggtgctggcggcttgtctgcgcgca
gactgctgtgaaatctggactgacgttgacggcgtgtacacctgcgacccgcgtcaggtt
ccagatgcgcgtctgctgaaatcaatgtcttatcaggaagcgatggagctgtcctacttt
ggcgccaaggtcctgcacccccgcaccatcgcgcccatcgcccagttccagatcccttgc
ctgattaaaaataccggtaatcctcaggcaccgggcacgttgattggtgccagtagcaac
gaagatggtctgccggtgaaagggatctctaacctgaataatatggccatgttcaacgtc
tctggacctggcatgaaggggatggtcgggatggcggcgcgcgtctttgccaccatgtcg
cgggcagggatttccgtagtgctgatcacccagtcctcttctgagtacagcatcagcttc
tgtattgcccaggccgattgtgcccgcgcgaagaaggcgatggaagatgagttctatctg
gagctgaaagaggggctgctggagccgctcgccatcatggagcggctggcgattatctcc
gtcgtgggtgatggcatgcgcacgctgcgtggcatttcggccaagttcttcgccgccctg
gcacgtgccaatatcaatatcgtggcgattgcccagggttcctccgagcgctcaatttca
gtggtggtgagtaacgacgatgcgacaaccggcgtgcgcgtgactcatcaaatgctgttc
aataccgatcaggttatcgaagtattcgtgattggggtcggtggcgtcggcggggcgctg
ctggagcagcttaaacgtcagcagtcctggctgaaaaacaaacatatcgatctgcgggtg
tgcggcgttgctaactcgaaagcgatgctgacccacgtgcatggcctgaacctcgacaac
tggcaggcagagcttgcggaggcgaaagagccgttcaacctggggcgtctgattcgcctg
gtgaaagaataccatttgctgaacccggtgattgttgactgtacctccagccaggcggtg
gcggaccagtatgccgatttcctgcgcgaaggcttccacgtggtaacgccgaacaaaaag
gccaatacctcatcaatggactactatcatgaactgcgccaggcggcggcaggttcacga
cgcaagttcctctatgacaccaacgttggcgcggggttgccggttatcgaaaacctgcaa
aatctgctgaacgccggggatgagttgcagcgcttctcgggcattctttccggttcactc
tcttttattttcgggaagctggatgagggaatgagcctgtcagaagcaacgatcctggcg
cggggaatgggttataccgaaccggacccgcgtgacgatctctctggaatggacgtagcg
cgtaaattgttgattctggtacgtgaaaccgggcgtgagctcgagcttcacgatattgtt
gtggagtcggtactgcctgagagcttcgatgctaccggtgacaccgagagttttatggcg
cgtctgccggagctggatgccgtgtttgccgatcgggtggcgaaagcccgtgatgaaggt
aaagttctgcgctatgttggcaatatcgaagacgatggcgtatgccgggtgaagattgcc
gaagtggacggtaacgatccgctgtacaaagtgaaaaatggtgagaacgccctggccttc
tacagccactattatcaaccgctgccgctggtcctgcgcggctacggtgcagggaacgat
gtgacggccgcgggcgtgtttgccgacctgctgcgcaccctgtcatggaagttaggagtc
taa
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