Zalophus californianus (California sea lion): 113908976
Help
Entry
113908976 CDS
T07874
Symbol
JAK1
Name
(RefSeq) tyrosine-protein kinase JAK1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca01521
EGFR tyrosine kinase inhibitor resistance
zca04151
PI3K-Akt signaling pathway
zca04217
Necroptosis
zca04380
Osteoclast differentiation
zca04550
Signaling pathways regulating pluripotency of stem cells
zca04620
Toll-like receptor signaling pathway
zca04621
NOD-like receptor signaling pathway
zca04630
JAK-STAT signaling pathway
zca04658
Th1 and Th2 cell differentiation
zca04659
Th17 cell differentiation
zca05140
Leishmaniasis
zca05145
Toxoplasmosis
zca05152
Tuberculosis
zca05160
Hepatitis C
zca05161
Hepatitis B
zca05162
Measles
zca05163
Human cytomegalovirus infection
zca05164
Influenza A
zca05165
Human papillomavirus infection
zca05166
Human T-cell leukemia virus 1 infection
zca05167
Kaposi sarcoma-associated herpesvirus infection
zca05168
Herpes simplex virus 1 infection
zca05169
Epstein-Barr virus infection
zca05171
Coronavirus disease - COVID-19
zca05200
Pathways in cancer
zca05203
Viral carcinogenesis
zca05212
Pancreatic cancer
zca05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
113908976 (JAK1)
04151 PI3K-Akt signaling pathway
113908976 (JAK1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
113908976 (JAK1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
113908976 (JAK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
113908976 (JAK1)
04621 NOD-like receptor signaling pathway
113908976 (JAK1)
04658 Th1 and Th2 cell differentiation
113908976 (JAK1)
04659 Th17 cell differentiation
113908976 (JAK1)
09158 Development and regeneration
04380 Osteoclast differentiation
113908976 (JAK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113908976 (JAK1)
05203 Viral carcinogenesis
113908976 (JAK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
113908976 (JAK1)
09162 Cancer: specific types
05212 Pancreatic cancer
113908976 (JAK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
113908976 (JAK1)
05161 Hepatitis B
113908976 (JAK1)
05160 Hepatitis C
113908976 (JAK1)
05171 Coronavirus disease - COVID-19
113908976 (JAK1)
05164 Influenza A
113908976 (JAK1)
05162 Measles
113908976 (JAK1)
05168 Herpes simplex virus 1 infection
113908976 (JAK1)
05163 Human cytomegalovirus infection
113908976 (JAK1)
05167 Kaposi sarcoma-associated herpesvirus infection
113908976 (JAK1)
05169 Epstein-Barr virus infection
113908976 (JAK1)
05165 Human papillomavirus infection
113908976 (JAK1)
09171 Infectious disease: bacterial
05152 Tuberculosis
113908976 (JAK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
113908976 (JAK1)
05140 Leishmaniasis
113908976 (JAK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
113908976 (JAK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
zca01001
]
113908976 (JAK1)
Enzymes [BR:
zca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
113908976 (JAK1)
Protein kinases [BR:
zca01001
]
Non-receptor tyrosine kinases
JAK family [OT]
113908976 (JAK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
ABC1
SH2
RIO1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
113908976
NCBI-ProteinID:
XP_027425624
EnsemblRapid:
ENSZCAG00025000597
UniProt:
A0A6J2B1B8
LinkDB
All DBs
Position
4:complement(53155422..53279676)
Genome browser
AA seq
1153 aa
AA seq
DB search
MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVLFYLADREPLRLGNGEYTAEEL
CIRAAQECRISPLCHNLFALYDENTKLWYAPNRTITVDDKTSLRLHYRMRFYFTNWHGTN
DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
WFHPNDSGNVLYYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKHKKDEEKNKIR
EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
CFEKSEVLGGQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFVLK
RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIVQGEHLGRGTRTHIYSGT
LVDYKDDEGTSEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV
ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL
LAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT
TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI
MRDINKLEEQNPDIVSERKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT
GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS
GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD
FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD
YSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPRHCPDEVYQLMRKCWEFQPSNRTT
FQNLIEGFEALLK
NT seq
3462 nt
NT seq
+upstream
nt +downstream
nt
atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgagg
agctccaagaagactgaggtgaatctggaggcccctgagccaggggtggaagtgctcttc
tatcttgctgatagggagcccctccgactgggcaacggagagtacacggcggaggagctg
tgcatcagggccgcacaggaatgccgtatctctcctctgtgtcacaacctctttgccctg
tatgatgagaacaccaagctctggtatgccccgaatcgcaccatcactgttgatgacaag
acatcgctccggctccactaccggatgaggttttatttcaccaactggcacgggaccaat
gataatgagcagtctgtatggcgacattctccaaagaagcagaaaaatggctatgagaaa
aaaaaagtcccagatgcaacccctctccttgacgccagctctctggaatatctgtttgct
cagggacaatatgatttggtcaaatgcctggctcccattcgagaccccaagaccgagcag
gatgggcacgatatcgagaacgagtgtctgggaatggctgtcctggccatctcccactac
gccatgatgaagaagatgcagttgccagaactgcccaaggacatcagctacaagcgatat
attccagaaacattgaataagtccatcagacagaggaaccttctcaccaggatgcggata
aataacgttttcaaggatttcctgaaggaatttaacaacaagactatttgtgacagcagc
gtatctactcatgacctaaaggtgaaatacctagccaccttggaaactttgacaaaacat
tatggcgctgaaatatttgagacttccatgttactgatttcatcagaaaatgagatgaat
tggtttcatccgaatgacagtggaaatgttctctactatgaagtgatggtaactggaaat
cttggaatccagtggagacagaaaccaaatgttgttcctgttgaaaaggaaaaaaacaaa
ctgaaacggaaaaaactggaaaataaacacaagaaggatgaggagaaaaacaaaatccgg
gaagaatggaacaatttttcttacttccctgaaatcacccacattgtaataaaggagtct
gtggtcagcatcaataagcaggacaacaaaaaaatggaactgaagctctcgtcccacgaa
gaggccttatcctttgtgtcgctggtcgacggctacttccggctcacggcagatgcccat
cattacctctgcaccgatgtggctcccccactgatcgtccacaacatacagaatggttgt
cacggtccaatctgcacagaatatgccatcaataagttgcggcaagaaggaagcgaggag
gggatgtatgtgctgaggtggagctgtaccgactttgacaatatcctcatgactgtcacc
tgctttgaaaaatctgaggtgctgggtggccaaaaacagttcaagaactttcagatcgag
gtgcagaagggccgctatagcctgcacggctcagaccgcagcttccccagcctgggggac
ctgatgagccacctcaagaagcagatcctgcgcacggacaacatcagcttcgtgctgaag
cgctgctgccagcccaagccccgagagatctccaatctgctggtggctactaagaaagcc
caggagtggcagcctgtctaccctatgagccagctgagttttgaccggatcctcaagaaa
gatattgtgcaaggcgagcaccttgggagaggcacacggacacacatctactccggtacc
ctggtggattacaaggatgacgaaggaacttccgaagagaagagaataaaagtgatcctc
aaagtcttagaccccagccacagggacatttctctggccttctttgaagcagccagcatg
atgaggcaggtctcccacaaacacatcgtgtacctctatggcgtctgtgtccgagacgtg
gagaatatcatggtggaggagtttgtggagggtgggcccctggatctcttcatgcaccgg
aaaagcgatgtcctcaccacaccatggaagttcaaagttgccaaacagctggccagcgcc
ctgagttatttggaggataaagacctggtccacggaaacgtgtgcacaaaaaaccttctc
ctggcccgtgagggcattgacagcgagtgcggcccgttcatcaagctcagtgaccctggc
atccccatcaccgtgctgtccaggcaagagtgcatagaacgaatcccatggattgctccc
gagtgtgttgaagactccaagaacctgagtgtggctgctgacaaatggagctttggaacc
acactttgggagatctgctacaatggcgagatccctctgaaagacaagaccctgattgag
aaagagagattctacgaaagccggtgccggccagtgacaccgtcttgcaaggagctggct
gaccttatgacccgctgcatgaactatgaccccaaccagagacccttcttccgagccatc
atgagagacatcaataaactggaagagcagaatccagacattgtttccgaaagaaagccg
gcaaccgaagtagaccccacacattttgaaaagcgattcttgaagaggatccgtgacttg
ggagagggccactttgggaaggttgagctctgcaggtatgaccctgagggggacaatacc
ggggagcaggtggcggtcaaatccctgaagcccgagagtggaggcaaccacatagctgac
ctgaagaaggaaattgaaatcctaaggaacctctatcatgagaacattgtgaagtacaaa
ggcatctgtacagaagatggaggaaatggtattaagctcatcatggaatttctgccttca
ggaagccttaaggaatatcttccaaagaataagaacaaaattaacctcaaacagcaatta
aaatatgccgttcagatttgtaaggggatggactatttgggttctcggcagtacgttcac
cgggacttggcagcaaggaatgtcctcgttgagagtgagcaccaagtgaaaattggagac
tttggtttgaccaaagcaattgaaactgacaaggagtactacacagtcaaggatgatcgg
gacagccctgtgttttggtatgctcccgaatgtttaattcagtgtaaattttatatcgcc
tctgacgtctggtcgtttggagtgactctgcatgagctgcttacttactgtgactcagat
tacagccccatggcgttgttcctgaaaatgataggcccaactcatggccaaatgacagtc
acaagacttgtgaatacattaaaagaaggaaaacgtttgccttgtccacgtcactgtcca
gatgaggtttatcaacttatgagaaaatgctgggaattccaaccatccaatcggacaact
tttcagaaccttattgaaggatttgaagcacttttaaaataa
DBGET
integrated database retrieval system
