KEGG T07874: 113926431

Zalophus californianus (California sea lion): 113926431

Entry

113926431         CDS       T07874

Symbol

HSD17B8

Name

(RefSeq) estradiol 17-beta-dehydrogenase 8

K13370

17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:1.1.1.62 1.1.1.239]

Organism

zca Zalophus californianus (California sea lion)

Pathway

zca00061

Fatty acid biosynthesis

zca00140

Steroid hormone biosynthesis

zca01100

Metabolic pathways

zca01212

Fatty acid metabolism

Module

zca_M00873

Fatty acid biosynthesis in mitochondria, animals

zca_M00976

C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone

Brite

KEGG Orthology (KO) [BR:zca00001]
09100 Metabolism
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    113926431 (HSD17B8)
   00140 Steroid hormone biosynthesis
    113926431 (HSD17B8)
Enzymes [BR:zca01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     113926431 (HSD17B8)
    1.1.1.239  3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
     113926431 (HSD17B8)

SSDB

Motif

Pfam:

adh_short_C2 adh_short KR Epimerase RmlD_sub_bind RNA_pol_Rpb1_4

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

EnsemblRapid:

UniProt:

LinkDB

Position

7:complement(116938711..116940899)

AA seq 259 aa
MASQLRLRSALALVTGAGSGIGRAVSVRLAREGATVAACDLDKAAACKTVWLLGGQGSEE
VAPGGAHAAFQADVSESGAVRRLLEQVQACFSRPPSVVVSCAGITRDEFLLRMSEDDWDK
VIAVNLKGIFLVTQAAAQALVSSGCHGSIINISSIIGKVGNMGQTNYAASKAGVIGLTQT
AARELGRHGIRCNSVLPGFITTPMTQKVPQKVLDKVAGMIPMGHMGDPEDVADVVAFLAS
EDSGYITGASVEVTGGLFM

NT seq 780 nt +upstreamnt +downstreamnt
atggcgtctcagctcaggctccgctccgcgctggccctggtcacaggcgcgggtagcggc
atcggccgggctgtcagtgtgcgcctcgccagagagggggccaccgtggccgcttgcgac
ctggacaaggcggcggcatgcaagacggtgtggctgctgggcgggcaggggagcgaggag
gtggcgcccggcggggcccacgccgccttccaggctgacgtgtctgagtccggggcggtc
aggcgcctgctggaacaagtacaggcctgcttttctcgcccgccgtctgtcgttgtgtcc
tgtgcggggatcacgagggatgagtttctgctccgcatgtctgaggatgactgggacaaa
gtcatagctgtcaatctcaagggcatctttctagtcactcaggctgcagcccaagccctg
gtgtccagtggttgccatgggtccatcatcaacatcagtagcatcatagggaaggtgggg
aacatgggacagacaaactatgcagcatccaaggctggagtgatcgggctcacccagacg
gcagctcgggagcttggacgacatgggatccgctgtaactctgtcctcccagggttcatt
acaacacccatgacacagaaagtgccacagaaagtgctggacaaggtggctggaatgatc
ccaatgggacacatgggggaccctgaggatgtggcagatgtggtggcattcttggcatct
gaagacagtggatacatcacaggggcctcggtggaagtcactggaggtcttttcatgtaa

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