Zalophus californianus (California sea lion): 113930616
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Entry
113930616 CDS
T07874
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca00010
Glycolysis / Gluconeogenesis
zca00020
Citrate cycle (TCA cycle)
zca00620
Pyruvate metabolism
zca00785
Lipoic acid metabolism
zca01100
Metabolic pathways
zca01200
Carbon metabolism
zca01210
2-Oxocarboxylic acid metabolism
zca04066
HIF-1 signaling pathway
zca04922
Glucagon signaling pathway
zca05230
Central carbon metabolism in cancer
zca05415
Diabetic cardiomyopathy
Module
zca_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
113930616 (PDHA1)
00020 Citrate cycle (TCA cycle)
113930616 (PDHA1)
00620 Pyruvate metabolism
113930616 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
113930616 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
113930616 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
113930616 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
113930616 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
113930616 (PDHA1)
Enzymes [BR:
zca01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
113930616 (PDHA1)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
113930616
NCBI-ProteinID:
XP_027463677
EnsemblRapid:
ENSZCAG00025020092
UniProt:
A0A6J2E9T9
LinkDB
All DBs
Position
X:complement(113882513..113898234)
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AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGVAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLRYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaaaatgctcgccgctgtctctcgcgtgttgtcgggcgtcgcccagaagccggca
agcagagtgctcgtggcctcccgtaattttgcaaatgatgctacatttgaaattaagaaa
tgcgatcttcatcggctagaagagggccctcctgtcaccacagtgctcaccagggaggac
gggctcaggtactacaggatgatgcagactgttcgccggatggagttaaaggcagatcag
ctgtataaacagaaaatcattcgtggtttctgtcacttgtgtgatggtcaggaagcttgt
tgtgtgggcctggaggccggcataaatcccacagaccatcttatcacagcctatcgggct
catggctttacctttacccgtggactttctgtccgagaaattctcgcagagcttacagga
cgaagaggaggctgtgctaaaggaaaaggtggatcgatgcatatgtatgccaagaacttc
tacgggggcaatggcatcgttggagctcaggtgcccctgggagcagggattgcgctggcc
tgtaagtacaacggaaaggacgaggtctgcttgactctgtatggcgacggtgctgccaat
cagggtcagatatttgaagcttacaacatggcagctttgtggaaattgccatgtattttc
atctgtgagaataaccgctatggaatggggacgtctgttgagagagcagcggctagcact
gattactacaagagaggcgacttcattcctgggctgagggtggatggaatggatatcttg
tgtgtccgggaggcaacaagatttgcagctgcttactgtagatctggaaaggggcccata
ctgatggagctacagacttaccgttaccatggacacagcatgagcgaccccggcgtcagt
taccgaacacgagaagagattcaggaagtaagaagtaagagtgaccctattatgcttctc
aaggatagaatggtgaacagcaatctggccagtgttgaagaattaaaggaaattgatgtt
gaagtgaggaaagaaattgaggatgctgcccagtttgccactgctgatcctgaaccgcct
ttggaagaactaggctatcacatttacagcagcgatccaccttttgaagttcggggtgca
aatcagtggatcaagtttaagtccatcagttaa
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