KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:yep00010 yep01200 yep01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:yep00010 yep01200 yep01230 yep01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:yep00010 yep00020 yep01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:yep00010 yep00020 yep00620 yep00785 yep01200 yep01210 yep01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:yep00020 yep01200 yep01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:yep00020 yep01200 yep01210 yep01230 yep01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:yep00020 yep01200 yep01210 yep01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:yep00030 yep01200 yep01100 yep01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:yep00030 yep01200 yep01100 yep01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:yep00030 yep01200 yep01230 yep01100 yep01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:yep00030 yep00230 yep01200 yep01230 yep01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:yep00030 yep01200 yep01100 yep01120]

Other carbohydrate metabolism
M00631 D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P [PATH:yep00040 yep00030 yep01100]
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH:yep00040 yep00030 yep01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:yep00052 yep01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:yep00500 yep01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:yep00500 yep01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:yep00520 yep01250 yep01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:yep00520 yep00052 yep01250 yep01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:yep00520 yep01250 yep01100]
M00761 Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N [PATH:yep00520 yep01100]
M00012 Glyoxylate cycle [PATH:yep00630 yep01200 yep01100 yep01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:yep00620 yep00710 yep01200 yep01100 yep01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:yep00430 yep00620 yep00720 yep01200 yep01100 yep01120]

Methane metabolism
Nitrogen metabolism
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:yep00910 yep01100 yep01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:yep00920 yep01100 yep01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:yep00190 yep01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:yep00190 yep01100]
M00150 Fumarate reductase, prokaryotes [PATH:yep00190 yep01100]
M00417 Cytochrome o ubiquinol oxidase [PATH:yep00190 yep01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:yep00190 yep01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:yep00061 yep01212 yep01100]
M00083 Fatty acid biosynthesis, elongation [PATH:yep00061 yep01212 yep01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:yep00061 yep00071 yep01212 yep01100]
M00087 beta-Oxidation [PATH:yep00071 yep01212 yep01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:yep00564 yep01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:yep00230 yep01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:yep00230 yep01232 yep01240 yep01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:yep00230 yep01232 yep01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:yep00230 yep00240 yep01232 yep01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:yep00240 yep01240 yep01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:yep00240 yep01232 yep01240 yep01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:yep00240 yep01232 yep01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:yep00260 yep00680 yep01200 yep01230 yep01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:yep00260 yep01230 yep01100 yep01110]
M00621 Glycine cleavage system [PATH:yep00260 yep00630 yep00785 yep01200 yep01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:yep00270 yep00920 yep01200 yep01230 yep01100 yep01110]
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:yep00260 yep00270 yep01230 yep01100]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:yep00270 yep01230 yep01100]
M00034 Methionine salvage pathway [PATH:yep00270 yep01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:yep00290 yep00770 yep01210 yep01230 yep01100 yep01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:yep00290 yep01230 yep01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:yep00290 yep01210 yep01230 yep01100 yep01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:yep00300 yep01230 yep01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:yep00220 yep01210 yep01230 yep01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:yep00220 yep01230 yep01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:yep00330 yep01230 yep01100]
M00970 Proline degradation, proline => glutamate [PATH:yep00330 yep01100]
M00879 Arginine succinyltransferase pathway, arginine => glutamate [PATH:yep00330 yep01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:yep00340 yep01230 yep01100 yep01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:yep00340 yep01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:yep00400 yep01230 yep01100 yep01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:yep00400 yep01230 yep01100 yep01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:yep00400 yep01230 yep01100 yep01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:yep00400 yep01230 yep01100]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:yep00480 yep01240 yep01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:yep00540 yep01100]
M00063 CMP-KDO biosynthesis [PATH:yep00540 yep01250 yep01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis [PATH:yep00540 yep01250 yep01100]

Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00127 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP [PATH:yep00730 yep01240 yep01100]
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:yep00730 yep01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:yep00740 yep01240 yep01100 yep01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:yep00750 yep01240 yep01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:yep00760 yep01240 yep01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:yep00770 yep01240 yep01100 yep01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:yep00770 yep01240 yep01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:yep00780 yep01240 yep01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:yep00785 yep01240 yep01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:yep00790 yep00670 yep01240 yep01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:yep00790 yep01240 yep01100]
M00140 C1-unit interconversion, prokaryotes [PATH:yep00670 yep01240 yep01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:yep00860 yep01240 yep01100 yep01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:yep00860 yep01240 yep01100 yep01110]
M00924 Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide [PATH:yep00860 yep01240 yep01100]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:yep00860 yep01240 yep01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:yep00130 yep01240 yep01100 yep01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:yep00130 yep01240 yep01100 yep01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00616 Sulfate-sulfur assimilation