KEGG Software
KEGG Data Viewers
There are six basic data viewers in KEGG, a generic viewer, called DBGET viewer, for all data types in a flat-file view and five viwers for specific data types including pathway maps, Brite hierarchies, KEGG modules, Network variation maps and genome maps.| KEGG WebLinks | REST-style URLs for the six data viewers: DBGET viewer, Pathway viewer, Brite viewer, Module viewer, Network viewer and Genome Browser. Among them Pathway viewer, Brite viewer and Genome browser are JavaScript based applications with analytica features and are called KEGG Web Apps. |
KEGG Analysis Tools
The following analysis tools are developed and maintained by Kanehisa Laboratories.| KEGG Mapper | KEGG mapping against PATHWAY/BRITE/MODULE databases, as well as NETWORK/DISEASE databases for human data [reference] |
| KEGG Syntax | Tools for taxonomy based analysis of conserved genes, gene sets and gene orders among organisms and organism groups [reference] |
| KEGG Web Apps | Pathway viewer, Brite viewer and Genome browser with mapping capabilities, including advanced coloring of pathway maps |
| KEGG Annotation | Tools for assisting KO annotation, including the automatic annotation servers shown below. |
| BlastKOALA GhostKOALA | KOALA family tools for automatic annotation of genome and metagenome sequences with subsequent KEGG Mapper analysis [reference] |
GenomeNet Analysis Tools
The following web servers are maintained by Kyoto University Bioinformatics Center as part of its GenomeNet service.| KofamKOALA | Another KOALA family tool for automatic KO assignment and KEGG mapping [reference] |
| KAAS | The original KEGG automatic annotation server [reference] |
| KEGG OC | KEGG OC viewer for browsing and analyzing ortholog clusters (OCs) computationally generated from the KEGG SSDB database [reference] |
| SIMCOMP SUBCOMP | Chemical structure similarity search against KEGG COMPOUND, KEGG DRUG, and other databases. SIMCOMP is based on 2D graph representation, while SUBCOMP is based on bit-string representation of chemical structures [references] |
| KCaM | Glycan structure similarity search against KEGG GLYCAN using tree structure comparison methods [reference] |
| E-zyme | Computational assignment of EC number sub-subclasses from chemical structure transformation patterns of substrates and products [references] |
| E-zyme2 | Identification of enzyme genes using chemical structure alignments of substrate-product pairs [references] |
| PathPred | Prediction of microbial biodegradation pathways and plant second metabolite biosynthesis pathways using reaction patterns in KEGG RCLASS [references] |
| GENIES | Gene network prediction from heterogeneous data sets using kernel methods and partially known network information [references] |
| DINIES | Drug-target interaction network prediction from various types of biological data including chemical structures, drug side effects, amino acid sequences and protein domains [references] |
iKeg: User-Side Applications
User-side applications making use of the KEGG services are collectively called iKeg, or personalized KEGG.KegTools are Java-based desktop applications that run on the Mac OS X, Windows, and Linux platforms. They were developed by Kanehisa Laboratories, but are no longer supported.
| KegHier | for browsing and searching BRITE functional hierarchies as well as for manipulating locally created hierarchical text files |
| KegArray | for analysis of transcriptome data (gene expression profiles) and metabolome data (compound profiles) with capabilities of KEGG pathway mapping and BRITE mapping |
| KegDraw | for drawing chemical compound structures and glycan structures with capabilities to search against the KEGG databases |
Last updated: July 1, 2026