GENES Addendum Category
KEGG GENES used to contain only the complete genome sequences until the introduction of the Addendum (ag) category, which is a manually created, publication-based collection of functionally characterized proteins. This category has been used to fill the gaps of missing sequence data in the KEGG pathway maps, where no corresponding genes could be found in KEGG organisms (complete genomes). It is also used to create various sequence data collections including antimicrobial resistance, EC numbers and CYP nomenclature.
KEGG Sequence Data Collection
BRITE table files
For characterizing and predicting antimicrobial resistance (see KEGG Pathogen) the following collections of Addendum sequences are created.
FASTA sequence files
The corresponding FASTA sequence files are available as follows.
For characterizing and predicting antimicrobial resistance (see KEGG Pathogen) the following collections of Addendum sequences are created.
- Antimicrobial resistance: beta-Lactamase genes
- Antimicrobial resistance: Aminoglycoside resistance genes
- Antimicrobial resistance: Tetracycline resistance genes
- Antimicrobial resistance: Macrolide resistance genes
- Antimicrobial resistance: Other resistance genes
FASTA sequence files
The corresponding FASTA sequence files are available as follows.
Phylogenetic trees
Phylogetic relationships of sequence data together with KEGG KO assignments (click on the Color button) are shown below for each collection of antimicrobial resistance genes. Each tree has been generated using clustalw and phylip packages.
- beta-Lactamase genes
class A
class D
class C
class B - Aminoglycoside resistance genes
- Tetracycline resistance genes
- Macrolide resistance genes
- Phenicol | Sulfonamide | Trimethoprim | Quinolone | Rifamycin | Fosfomycin resistance genes
Last updated: May 1, 2021