KEGG   ORTHOLOGY: K00188
Entry
K00188                      KO                                     
Symbol
vorD
Name
2-oxoisovalerate ferredoxin oxidoreductase delta subunit [EC:1.2.7.7]
Pathway
map00280  Valine, leucine and isoleucine degradation
map01100  Metabolic pathways
map01210  2-Oxocarboxylic acid metabolism
Reaction
R07160  3-methyl-2-oxobutanoate:ferredoxin oxidoreductase (decarboxylating;CoA-2-methylpropanoylating)
R08566  4-methyl-2-oxopentanoate:ferredoxin oxidoreductase (decarboxylating; CoA-3-methylbutanoylating)
R08567  (S)-3-methyl-2-oxopentanoate:ferredoxin oxidoreductase (decarboxylating; CoA-2-methylbutanoylating)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    K00188  vorD; 2-oxoisovalerate ferredoxin oxidoreductase delta subunit
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.7  With an iron-sulfur protein as acceptor
    1.2.7.7  3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)
     K00188  vorD; 2-oxoisovalerate ferredoxin oxidoreductase delta subunit
Enzymes of 2-oxocarboxylic acid metabolism [br01601.html]
 2-Oxoacid oxidizing enzymes
  K00188
Other DBs
COG: COG1144
GO: 0043807
Genes
PFAA: MM59RIKEN_15740
EVN: NQ558_06000
CHYL: CE91St63_20520
HPRF: HLPR_01110(porD)
PBU: L21SP3_01136
PBP: STSP1_01191
PBAS: SMSP2_01217
VBC: C5Q97_08000
SLR: L21SP2_0405
MMP: MMP1273(vorC)
MMQ: MmarC5_0318
MMX: MmarC6_1400
MMZ: MmarC7_0519
MMD: GYY_07200
MMAK: MMKA1_14980
MMAO: MMOS7_13800
MMAD: MMJJ_15720
MVN: Mevan_0585
MVO: Mvol_0720
MTH: MTH_703
MMG: MTBMA_c10900(vorC)
MWO: MWSIV6_1079(vorC)
MTEE: MTTB_10540
METC: MTCT_0631
METE: tca_00678
METZ: METMT2_0339
METK: FVF72_08035
MTHM: FZP57_05120
METJ: FZP68_01105
MRU: mru_1433(vorC)
MSI: Msm_0331
MMIL: sm9_0694(vorC)
MOL: YLM1_0934
MARO: MarbSA_03680
METV: K4897_02170
MEL: Metbo_2454
MEW: MSWAN_0187
METH: MBMB1_0178
MFC: BRM9_2125(vorC)
MFI: DSM1535_1555
MCUB: MCBB_0193(vorC)
MSUB: BK009_10645
METN: BK008_06270
METT: CIT01_01270
METO: CIT02_06150
MEME: HYG87_02760
MFEG: GCM10025860_09900
MFV: Mfer_0506
PFU: PF0970
PFI: PFC_04080(vorD)
PHO: PH0679(PH0679)
PAB: PAB1471
PYN: PNA2_1293
PYA: PYCH_06650
PYS: Py04_1081
PYC: TQ32_04850(vorD)
TKO: TK1979
TON: TON_1477
TGA: TGAM_0266(vorD)
TSI: TSIB_1383
TBA: TERMP_01559
THE: GQS_08135(vorD)
THA: TAM4_1406
THM: CL1_1248
TLT: OCC_07496(vorD)
THS: TES1_1554
TNU: BD01_1942
TEU: TEU_01680(vorD)
TGY: X802_03770(vorD)
THV: ADU37_CDS14460
TCH: CHITON_0666
TPEP: A0127_05000(vorD)
TPIE: A7C91_04905(vorD)
TGG: A3K92_07960(vorD)
TCE: A3L02_06810(vorD)
TBS: A3L01_08185(vorD)
THH: CDI07_07395(vorD)
TSL: A3L11_01535(vorD)
TTD: A3L14_10580(vorD)
TPRF: A3L09_01310(vorD)
TRL: A3L10_07575(vorD)
TPAF: A3L08_01310(vorD)
THY: A3L12_04020(vorD)
TIC: FH039_11780
TCQ: TIRI35C_1960(vorD)
THEM: FPV09_09755
THEI: K1720_10010
PPAC: PAP_04305(vorD)
MBA: Mbar_A2173
MBY: MSBRM_2264
MBW: MSBRW_2568
MBAR: MSBR2_0147
MBAK: MSBR3_1066
MAC: MA_2911(vorC)
MMA: MM_3181(vorC)
MMAZ: MmTuc01_3277
MMJ: MSMAS_1508
MMAC: MSMAC_2851
MVC: MSVAZ_1286
MEK: MSKOL_1230
MLS: MSLAZ_2008
METM: MSMTP_1761
MEF: MSWH1_1307
MEQ: MSWHS_1391
MSJ: MSSAC_2723
MSZ: MSSIH_1391
MSW: MSSIT_1429
MTHR: MSTHT_0826
MTHE: MSTHC_2445
MHOR: MSHOH_1581
MFZ: AOB57_012375
MBU: Mbur_0607
MMET: MCMEM_1079
MELO: J7W08_03855
MMH: Mmah_1010
MHAZ: BHR79_08520
MPOT: BKM01_04770
MZH: Mzhil_0902
MPY: Mpsy_0059
MZI: HWN40_07270
MMAV: RE476_03225
MSEB: RE474_12875
MHZ: Metho_2048
MEHF: MmiHf6_00120
MEES: MmiEs2_10540
HAAA: AArcCO_0208(porD)
TAC: Ta0627
MER: MMINT_12450(vorD)
ABI: Aboo_0299
ACF: AciM339_0765
 » show all
Reference
PMID:8550513 (P.furiosus)
  Authors
Heider J, Mai X, Adams MW
  Title
Characterization of 2-ketoisovalerate ferredoxin oxidoreductase, a new and reversible coenzyme A-dependent enzyme involved in peptide fermentation by hyperthermophilic archaea.
  Journal
J Bacteriol 178:780-7 (1996)
DOI:10.1128/JB.178.3.780-787.1996
Reference
PMID:8550425
  Authors
Kletzin A, Adams MW
  Title
Molecular and phylogenetic characterization of pyruvate and 2-ketoisovalerate ferredoxin oxidoreductases from Pyrococcus furiosus and pyruvate ferredoxin oxidoreductase from Thermotoga maritima.
  Journal
J Bacteriol 178:248-57 (1996)
DOI:10.1128/JB.178.1.248-257.1996
  Sequence
[pfu:PF0970]
Reference
PMID:9108258
  Authors
Tersteegen A, Linder D, Thauer RK, Hedderich R
  Title
Structures and functions of four anabolic 2-oxoacid oxidoreductases in Methanobacterium thermoautotrophicum.
  Journal
Eur J Biochem 244:862-8 (1997)
DOI:10.1111/j.1432-1033.1997.00862.x
  Sequence
[mmg:MTBMA_c10900]
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