KEGG   ORTHOLOGY: K03389
Entry
K03389                      KO                                     
Symbol
hdrB2
Name
heterodisulfide reductase subunit B2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
Pathway
map00680  Methane metabolism
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01200  Carbon metabolism
Module
M00356  Methanogenesis, methanol => methane
M00357  Methanogenesis, acetate => methane
M00563  Methanogenesis, methylamine/dimethylamine/trimethylamine => methane
M00567  Methanogenesis, CO2 => methane
Reaction
R11928  CoB,CoM,ferredoxin:coenzyme F420 oxidoreductase
R11931  CoB,CoM:ferredoxin oxidoreductase
R11943  CoB,CoM,ferredoxin:H2 oxidoreductase
R11944  coenzyme B,coenzyme M,ferredoxin:formate oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K03389  hdrB2; heterodisulfide reductase subunit B2
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.7  With an iron-sulfur protein as acceptor
    1.8.7.3  ferredoxin:CoB-CoM heterodisulfide reductase
     K03389  hdrB2; heterodisulfide reductase subunit B2
   1.8.98  With other, known, physiological acceptors
    1.8.98.4  coenzyme F420:CoB-CoM heterodisulfide,ferredoxin reductase
     K03389  hdrB2; heterodisulfide reductase subunit B2
    1.8.98.5  H2:CoB-CoM heterodisulfide,ferredoxin reductase
     K03389  hdrB2; heterodisulfide reductase subunit B2
    1.8.98.6  formate:CoB-CoM heterodisulfide,ferredoxin reductase
     K03389  hdrB2; heterodisulfide reductase subunit B2
Other DBs
COG: COG2048
Genes
TIG: THII_2280
THIS: HZT40_21385
TUN: J9260_16770
TLO: J9253_18170
TSB: HMY34_11225
TANI: J8380_05655
TWN: L2Y54_05835
TLC: RCF98_07610
TSJ: L3K52_04625
TVI: Thivi_3111
TMB: Thimo_0248
TSY: THSYN_16425
HHC: M911_11215 M911_11235
EBS: ECTOBSL9_0282 ECTOBSL9_0286
TGR: Tgr7_2211 Tgr7_2215
TKM: TK90_0633 TK90_0637
TNI: TVNIR_3244(hdrB_[H]) TVNIR_3248(hdlB_[H])
TVR: TVD_10625 TVD_10645
APRS: BI364_13790 BI364_13810
AAEO: BJI67_04065 BJI67_04085
AFY: BW247_09910 BW247_09930
TBN: TBH_C2777
EPS: L0Y14_00985 L0Y14_11950
SEDS: AAY24_12130
SLIM: SCL_2520
ACII: C4901_01555 C4901_12955 C4901_12975
ATY: A9R16_001325 A9R16_003995 A9R16_004015
REV: HUE57_00445
ENM: EBS_2145(hdrB)
SHD: SUTH_02769(hdrB)
NPV: OHM77_12515 OHM77_12790
TBD: Tbd_1645
SDR: SCD_n01881(hdrB)
SULF: CAP31_01845 CAP31_01865
SPLB: SFPGR_13340 SFPGR_29420(hdrB) SFPGR_29460
SNIV: SFSGTM_27260(hdrB) SFSGTM_27300
SLAC: SKTS_06180(hdrB) SKTS_11890
DDZ: DSYM_23140
HDN: Hden_0690 Hden_0694
BLAG: BLTE_14980
RHC: RGUI_1278 RGUI_1282
AEP: AMC99_00775 AMC99_00779
QSO: IRL76_11080 IRL76_11100
SRF: LHU95_22225
RAP: RHOA_4359
VSU: P3M64_01085
AFR: AFE_2550(sdhC) AFE_2554 AFE_2586
AFE: Lferr_2178 Lferr_2184 Lferr_2215
ACU: Atc_2347 Atc_2351 Atc_2393
ACZ: Acaty_c2190 Acaty_c2194 Acaty_c2236
AFI: Acife_2471 Acife_2475 Acife_2519
AFJ: AFERRID_05100 AFERRID_05140 AFERRID_05460
ATX: GCD22_01577(hdrB1) GCD22_02661(hdrB1) GCD22_03145(hdrB) GCD22_03149(hdrB1) GCD22_03192(hdrB1)
AFP: K1Y48_08825 K1Y48_09030 K1Y48_09050
ACIY: MQE22_02535 MQE22_02745 MQE22_02765
GSU: GSU0091(hdrB)
GSK: KN400_0066(hdrB)
GME: Gmet_3425(hdrB)
GPI: GPICK_06755 GPICK_15690
GAO: A2G06_15985
GBZ: JZM60_06215
GEM: GM21_0030
GEB: GM18_0027 GM18_3238
GEF: FO488_02640
GUR: Gura_0150 Gura_3582
GEO: Geob_3724(hdrB)
GLO: Glov_0862
TAMM: GEAMG1_2374
GBM: Gbem_0031(hdrB)
GBN: GEOBRER4_00290(hdrB)
GER: KP004_19745
GSUB: KP001_16570
GNT: KP003_19735
GPL: M1B72_22220
DDS: Ddes_2099
DFI: AXF13_12660
DPG: DESPIGER_1699
DEF: CNY67_01585
DTR: RSDT_0566(hdrB)
DFL: DFE_0755 DFE_2492
PSYF: N1030_00480 N1030_03920
DSB: LN040_10945 LN040_16910
DMA: DMR_01910(hdrB)
DCB: C3Y92_00560
DGG: DGI_1049(hdrB)
DDE: Dde_1208 Dde_3525
DMS: E8L03_02835 E8L03_07130 E8L03_12010
DSA: Desal_0601
DHY: DESAM_21331
DAF: Desaf_1861 Desaf_2882
DAS: Daes_0784
DPI: BN4_11859(hdrB)
DEJ: AWY79_02120 AWY79_07320
PSEL: GM415_09675 GM415_15600
DDN: DND132_1387
PSEF: PSDVSF_30230(hdrB)
PPOR: JCM14722_30790 JCM14722_31300(hdrB)
PNW: SYK_07270
PTHE: LF599_14175
DSX: GD604_12430
DSD: GD606_06815 GD606_11675
PBIZ: LWC08_06295
DVU: DVU_2403(hdrB)
DVL: Dvul_0827
DVM: DvMF_0323
DVG: Deval_2224
CLIH: KPS_000424
DBA: Dbac_0849 Dbac_2343
DOA: AXF15_11205
DESU: NLA06_01270 NLA06_04410
THEW: TDMWS_00860(hdrB)
DRT: Dret_0197 Dret_0416 Dret_2316
DLM: DPPLL_25810 DPPLL_26230(hdrB)
DPR: Despr_0010
DEO: CAY53_08855
DBK: DGMP_38710
ECOM: QTN59_02655
DOL: Dole_1160
DAT: HRM2_22770(hdrD2')
DTO: TOL2_C02630 TOL2_C17920(hdlB)
DOV: DSCO28_20260 DSCO28_27610
DWD: DSCW_61090
DALK: DSCA_54680
DML: Dmul_28870(hdrB)
DLI: dnl_31770
DMM: dnm_100780
DEK: DSLASN_10520 DSLASN_24460 DSLASN_32850(hdrB) DSLASN_44320
DAO: Desac_0668 Desac_0823
DTI: Desti_0008 Desti_0172 Desti_4259 Desti_5029
SFU: Sfum_0819 Sfum_1805 Sfum_4093
DAX: FDQ92_07505
DBR: Deba_0986
DMP: FAK_04490
TID: Thein_0805 Thein_1781
TCM: HL41_00015 HL41_09205 HL41_09230
THET: F1847_06840 F1847_06870
TAV: G4V39_00785
TMAI: FVE67_04820
BTS: Btus_2497
KYR: CVV65_12495
CEU: A7L45_12280
CTHD: CDO33_09910
RCH: RUM_10960
RUM: CK1_05040
SMAN: C12CBH8_20530(hdrB)
PETR: QKW49_07885
SWO: Swol_0395
SLP: Slip_1198 Slip_1201 Slip_2074
SALQ: SYNTR_0262
DMT: DESME_05490 DESME_05510
SGY: Sgly_1901
DOR: Desor_3501 Desor_3504 Desor_4440
DAI: Desaci_2522
DCA: Desca_0815 Desca_2380
PTH: PTH_1412(HdrB)
DRM: Dred_0357 Dred_0634 Dred_1326
DRU: Desru_2699 Desru_3379
DFG: B0537_03640 B0537_06280
DAE: Dtox_1349 Dtox_1352 Dtox_3573
DKU: Desku_0192 Desku_1435 Desku_1484 Desku_1501 Desku_3101 Desku_3118
DAU: Daud_0564 Daud_1251 Daud_1881
TFR: BR63_02770 BR63_10500
AACX: DEACI_0471 DEACI_0907 DEACI_2407 DEACI_2890 DEACI_2894
TJR: TherJR_1776 TherJR_1954
DGI: Desgi_1604 Desgi_2164 Desgi_3697
HMO: HM1_2007
HCV: FTV88_1703(hdrB)
SAY: TPY_3530
SAP: Sulac_1385
STHR: BXT84_01295 BXT84_01315 BXT84_06255
HFV: R50_0689 R50_0693 R50_1170
CTHM: CFE_1266 CFE_1630 CFE_1753
BYL: A4V09_16725
BPRO: PMF13cell1_01670(lutA)
BLAB: EYS05_14040
BWX: NQ550_09255
BMAS: LK422_10005
BLAR: LC508_15300
BLUI: Blut17040_18890
BCOC: BLCOC_07520(sdhE)
MFOR: NQ534_19200
CMIU: B1H56_01475
CHY: CHY_0714 CHY_0929 CHY_1229
ADG: Adeg_1334
TPZ: Tph_c15470
MTA: Moth_0440 Moth_0810 Moth_1195
MTHO: MOTHE_c03760 MOTHE_c07550(lutA2) MOTHE_c11710
MTHZ: MOTHA_c04650 MOTHA_c08490(lutA2) MOTHA_c12580
NTH: Nther_2664
NCD: ACONDI_03087(sdhE)
MANA: MAMMFC1_00469
STED: SPTER_13750(sdhE_1)
CALK: HUE98_11610
SHI: Shel_17760
PARN: NBH00_11860
AFO: Afer_0965
CAN: Cyan10605_2788 Cyan10605_2791
SYL: AWQ21_15430 AWQ21_15445
CYC: PCC7424_1698 PCC7424_1701
PPSU: NO713_02682(hdrB2) NO713_02685(hdrB1)
OAC: Oscil6304_5892 Oscil6304_5896
NOP: Nos7524_5056 Nos7524_5059
RSIN: B6N60_02611 B6N60_02614
DLY: Dehly_0731
DEW: DGWBC_1419
DFO: Dform_00942(hdrB)
DETH: HX448_06340
THUG: KNN16_08290
TRO: trd_0154
TNR: Thena_1330
TACI: TDSAC_1307
OTE: Oter_3676
FPES: NXS98_02660
TTF: THTE_4308
TSU: Tresu_1314
TBE: Trebr_2036
TRC: DYE49_06635
TPER: IWA51_04955
MSIL: METEAL_37390(hdrB)
MSEA: METESE_33960(hdrB)
FVA: FV113G1_17840
FUL: C4N20_13315
FMO: C4N19_02860
IPO: Ilyop_2566
BOA: Bovatus_04657
BCEL: BcellWH2_01252
DYS: G7050_05250
DYH: G7051_05510
APS: CFPG_239
OSP: Odosp_0422
BUY: D8S85_20545
BVIR: I6J59_08950
BFH: F1611_02860
AFD: Alfi_2100
ALD: GFH31_00870 GFH31_08500
AOK: A3BBH6_05100
ACOU: A5CBH24_14820
ADA: A5CPEGH6_16750
AIT: AI2BBH_11660
ASEN: NQ519_03360
AIU: NQ491_07880
BACC: BRDCF_p1059(hdrB) BRDCF_p1818
ANF: AQPE_4790
CTE: CT1245
CPC: Cpar_0950
CLZ: BIU88_04790
CCH: Cag_1028
CPH: Cpha266_1261
CLI: Clim_1201
PVI: Cvib_0844
PLT: Plut_1108
PPH: Ppha_1307
CTS: Ctha_0137
AAE: aq_400(hdrB)
HYA: HY04AAS1_1077 HY04AAS1_1081
HHO: HydHO_1072 HydHO_1076
HYS: HydSN_1099 HydSN_1103
HTH: HTH_1878(hdrB1) HTH_1882(hdrB2)
HTE: Hydth_1860 Hydth_1864
TAL: Thal_1343 Thal_1347
TRD: THERU_00170 THERU_00190
TTK: TST_1519(hdrB)
CABY: Cabys_1918
TYE: THEYE_A1368
BANA: BARAN1_0332
BIH: BIP78_0147
FSH: Q2T83_12640 Q2T83_12660
MJA: MJ_0743 MJ_0863
MFE: Mefer_1123
MVU: Metvu_0280 Metvu_0442
MFS: MFS40622_1299
MIF: Metin_0496
MJH: JH146_1037
MESG: MLAUSG7_0227(hdrB) MLAUSG7_1015(hdrB)
MESA: MLASG1_0762(hdrB) MLASG1_1448(hdrB)
MIG: Metig_0266 Metig_0423
MMP: MMP1053(hdrB2) MMP1155(hdrB1)
MMQ: MmarC5_0432 MmarC5_0540
MMX: MmarC6_1516 MmarC6_1605
MMZ: MmarC7_0307 MmarC7_0403
MMD: GYY_06105 GYY_06620
MMAK: MMKA1_12180(hdrB) MMKA1_13330(hdrB)
MMAO: MMOS7_11480(hdrB) MMOS7_12630(hdrB)
MMAD: MMJJ_16900 MMJJ_17970(lutA)
MAE: Maeo_0308
MVN: Mevan_0376 Mevan_0475
MVO: Mvol_0794 Mvol_0808
MOK: Metok_0032
METF: CFE53_06410(hdrB)
MTH: MTH_1879
MMG: MTBMA_c04500(hdrB)
MWO: MWSIV6_0410(hdrB)
MTEE: MTTB_11770
METC: MTCT_1717
METE: tca_01815(lutA)
METZ: METMT2_0213
METK: FVF72_02310(hdrB)
MTHM: FZP57_01925(hdrB)
METJ: FZP68_06955(hdrB)
MST: Msp_1013(hdrB1)
METB: AW729_10830
MEIS: PXD04_02625(hdrB)
MRU: mru_0817(hdrB1)
MSI: Msm_0795
MEB: Abm4_1308(hdrB2)
MMIL: sm9_1716(hdrB3)
MEYE: TL18_07635
MOL: YLM1_0405
MARO: MarbSA_07060
METV: K4897_07520(hdrB)
MEL: Metbo_0701
MEW: MSWAN_1552
METH: MBMB1_1274(hdrB)
MFC: BRM9_0490(hdrB1)
MFI: DSM1535_0471(hdrB)
MCUB: MCBB_1489(hdrB3)
MSUB: BK009_05285
METN: BK008_00830
METT: CIT01_08470(hdrB)
METO: CIT02_11685(hdrB)
MEME: HYG87_08910(hdrB)
MFEG: GCM10025860_26190
MFV: Mfer_0739
MKA: MK0572(hdrB)
AFU: AF_0271 AF_1375
AFG: AFULGI_00002640 AFULGI_00014870
APO: Arcpr_1553
AVE: Arcve_1120
AST: Asulf_01079 Asulf_01822
FPL: Ferp_0838 Ferp_1393
GAC: GACE_0708 GACE_0931
GAH: GAH_01705 GAH_02035
MBA: Mbar_A0639
MBY: MSBRM_3200
MBW: MSBRW_0364
MBAR: MSBR2_3160
MBAK: MSBR3_3156
MAC: MA_4237(hdrB)
MMA: MM_0980
MMAZ: MmTuc01_1010
MMJ: MSMAS_0319
MMAC: MSMAC_0323 MSMAC_2578
MVC: MSVAZ_3214
MEK: MSKOL_3182
MLS: MSLAZ_2785
METM: MSMTP_0364
MEF: MSWH1_2878
MEQ: MSWHS_2114
MSJ: MSSAC_3849
MSZ: MSSIH_3381
MSW: MSSIT_3450
MTHR: MSTHT_1573
MTHE: MSTHC_1716
MHOR: MSHOH_0417 MSHOH_1798
MFZ: AOB57_006960(hdrB)
MBU: Mbur_1517(hdrB)
MMET: MCMEM_1990
MELO: J7W08_08845(hdrB)
MMH: Mmah_1786
MHAZ: BHR79_04740
MPOT: BKM01_00870
MEV: Metev_1472
MZH: Mzhil_0328
MPY: Mpsy_1377 Mpsy_2939
MZI: HWN40_01880(hdrB)
MMAV: RE476_08390(hdrB)
MSEB: RE474_01415(hdrB) RE474_04985(hdrB)
MHZ: Metho_0299
MEHF: MmiHf6_05700(sdhE)
MEES: MmiEs2_04320(sdhE)
MTP: Mthe_1573
MCJ: MCON_3283(hdrB)
MHI: Mhar_0604
MHU: Mhun_1837
MRTJ: KHC33_05220(hdrB)
MLA: Mlab_0240
MEM: Memar_0624
MBG: BN140_1727(hdrB)
MEMA: MMAB1_2222(hdrB)
MCHK: MchiMG62_07530 MchiMG62_19070
MSUM: OH143_09840(hdrB)
MRC: R6Y96_02595(hdrB)
MPI: Mpet_2472 Mpet_2478
MEND: L6E24_09280(hdrB)
MEFW: F1737_00660(hdrB)
MAQE: RJ40_06040(hdrB)
MFK: E2N92_06170(hdrB)
MOU: OU421_03585(hdrB)
MESB: L1S32_07185(hdrB)
MANQ: L1994_01135(hdrB)
MBN: Mboo_0589
MFO: Metfor_2602
MPL: Mpal_2240
MPD: MCP_1577(hdrB-1) MCP_2769(hdrB-3)
MEZ: Mtc_2474(hdrB-2)
RCI: RCIX595(hdrB-2) RRC257(hdrB-3)
MELU: MTLP_03930
TAR: TALC_01276
MAX: MMALV_13660
MER: MMINT_03230
MEAR: Mpt1_c02970(hdrB1) Mpt1_c08830(hdrB2)
MEUZ: KRP56_06640(hdrB)
MARC: AR505_0274
ABI: Aboo_0976
ACF: AciM339_1134
STO: STK_18700 STK_18740
SOH: D1869_10540 D1869_10560
SSO: SSO1129(hdrB-1) SSO1135(hdrB-2)
SOL: Ssol_2100 Ssol_2104
SSOA: SULA_2131 SULA_2135
SSOL: SULB_2132 SULB_2136
SSOF: SULC_2130 SULC_2134
SSHI: J5U23_02350 J5U23_02354
SCAS: SACC_10180 SACC_10220
SAI: Saci_0325(hdrB) Saci_0329
SACN: SacN8_01595 SacN8_01615
SACR: SacRon12I_01595 SacRon12I_01615
SACS: SUSAZ_01655 SUSAZ_01675
SIS: LS215_1193 LS215_1197
SIA: M1425_1096 M1425_1100
SIM: M1627_1160 M1627_1164
SID: M164_1086 M164_1090
SIY: YG5714_1092 YG5714_1096
SIN: YN1551_1762 YN1551_1766
SII: LD85_1214 LD85_1218
SIH: SiH_1057 SiH_1061
SIR: SiRe_0970 SiRe_0974
SIC: SiL_0976 SiL_0980
SULA: BFU36_00895 BFU36_00915
SULE: GFS03_06300 GFS03_06320
SULO: GFS33_11680 GFS33_11700
SULL: EWF20_12020 EWF20_12040
MSE: Msed_1542 Msed_1546
MEMJ: MJ1HA_1759 MJ1HA_1763
MCN: Mcup_0685 Mcup_0689
MHK: DFR87_11010 DFR87_11030
MPRU: DFR88_10570 DFR88_10590
MTEN: GWK48_01305 GWK48_01325
MJN: MjAS7_2640 MjAS7_2644
AHO: Ahos_1691 Ahos_1695
AMAN: B6F84_12585 B6F84_12605
ABRI: DFR85_11430 DFR85_11450
ASUL: DFR86_10765 DFR86_10785
AAMB: D1866_03535 D1866_03555
ACIH: HS5_01360 HS5_01400
SACD: HS1genome_0377 HS1genome_0381
SAZO: D1868_10015 D1868_10035
CSTY: KN1_04050 KN1_04090
STEP: IC006_0774 IC006_0778
SMET: RQ359_001050 RQ359_001054
SAHS: HS7_01160 HS7_01200
KCR: Kcr_0767
BARC: AOA65_1401(hdrB_2) AOA65_1887(hdrB_3) AOA65_1993(hdrB_4)
BARB: AOA66_1507(hdrB_1) AOA66_1731(hdrB_2)
LOKI: Lokiarch_01260(hdrB_1) Lokiarch_23590(hdrB_2) Lokiarch_39150(hdrB_3) Lokiarch_45510(hdrB_4)
LOB: NEF87_001640 NEF87_002004 NEF87_002031 NEF87_003525
PSYT: DSAG12_01137(hdrB_1) DSAG12_01146(hdrB_2) DSAG12_01161(hdrB_3) DSAG12_02807(hdrB_4) DSAG12_03223(hdrB_5) DSAG12_03725(hdrB_6) DSAG12_03952(hdrB_7)
 » show all
Reference
PMID:2121478
  Authors
Hedderich R, Berkessel A, Thauer RK
  Title
Purification and properties of heterodisulfide reductase from Methanobacterium thermoautotrophicum (strain Marburg).
  Journal
Eur J Biochem 193:255-61 (1990)
DOI:10.1111/j.1432-1033.1990.tb19331.x
  Sequence
[mmg:MTBMA_c04500]
Reference
PMID:8119281
  Authors
Setzke E, Hedderich R, Heiden S, Thauer RK
  Title
H2: heterodisulfide oxidoreductase complex from Methanobacterium thermoautotrophicum. Composition and properties.
  Journal
Eur J Biochem 220:139-48 (1994)
DOI:10.1111/j.1432-1033.1994.tb18608.x
  Sequence
[mmg:MTBMA_c04500]
Reference
PMID:15009189
  Authors
Mander GJ, Pierik AJ, Huber H, Hedderich R
  Title
Two distinct heterodisulfide reductase-like enzymes in the sulfate-reducing archaeon Archaeoglobus profundus.
  Journal
Eur J Biochem 271:1106-16 (2004)
DOI:10.1111/j.1432-1033.2004.04013.x
  Sequence
[apo:Arcpr_1553] [afu:AF_1375]
LinkDB

DBGET integrated database retrieval system