| Entry |
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| Symbol |
aksF
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| Name |
methanogen homoisocitrate dehydrogenase [EC: 1.1.1.87 1.1.1.-]
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| Pathway |
| map01110 | Biosynthesis of secondary metabolites |
| map01120 | Microbial metabolism in diverse environments |
| map01210 | 2-Oxocarboxylic acid metabolism |
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| Module |
| M00608 | 2-Oxocarboxylic acid chain extension, 2-oxoglutarate => 2-oxoadipate => 2-oxopimelate => 2-oxosuberate |
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| Reaction |
| R01934 | (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate:NAD+ oxidoreductase (decarboxylating) |
| R01936 | (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate:NAD+ oxidoreductase (decarboxylating) |
| R04862 | (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate:NAD+ oxidoreductase (decarboxylating) |
| R08214 | (-)-threo-iso(homo)2-citrate:NAD+ oxidoreductase (decarboxylating) |
| R08215 | (-)-threo-iso(homo)3-citrate:NAD+ oxidoreductase (decarboxylating) |
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| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09102 Energy metabolism
00680 Methane metabolism
K10978 aksF; methanogen homoisocitrate dehydrogenase
09105 Amino acid metabolism
00300 Lysine biosynthesis
K10978 aksF; methanogen homoisocitrate dehydrogenase
Enzymes [BR:ko01000]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.87 homoisocitrate dehydrogenase
K10978 aksF; methanogen homoisocitrate dehydrogenase
Enzymes of 2-oxocarboxylic acid metabolism [br01601.html]
2-Oxoacid chain elongation
K10978
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| Other DBs |
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| Genes |
» show all
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| Reference |
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| Authors |
Howell DM, Graupner M, Xu H, White RH |
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| Title |
Identification of enzymes homologous to isocitrate dehydrogenase that are involved in coenzyme B and leucine biosynthesis in methanoarchaea. |
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| Journal |
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| Sequence |
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| LinkDB |
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