KEGG ORTHOLOGY: K12665

ORTHOLOGY: K12665

Entry

K12665                      KO

Symbol

CYP26C

Name

cytochrome P450 family 26 subfamily C [EC:1.14.14.-]

Pathway

map00830

Retinol metabolism

map01100

Metabolic pathways

Reaction

R08390

R08392

Disease

H02083

Focal facial dermal dysplasia

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K12665  CYP26C; cytochrome P450 family 26 subfamily C
09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K12665  CYP26C; cytochrome P450 family 26 subfamily C
Cytochrome P450 [BR:ko00199]
Cytochrome P450, animal type
  CYP26 family
   K12665  CYP26C; cytochrome P450 family 26 subfamily C

Genes

HSA:	340665(CYP26C1)

PTR:

100610581

PPS:	100989646(CYP26C1)

GGO:

PON:

NLE:

HMH:

MCC:

MCF:	102132475(CYP26C1)

MTHB:

MNI:

CATY:

PANU:

TGE:

MLEU:

RRO:

RBB:

TFN:

PTEH:

CANG:

CJC:	100388017(CYP26C1)

SBQ:

101048691

CIMI:

108282302(CYP26C1)

MMUR:

LCAT:

PCOQ:

OGA:

MMU:	546726(Cyp26c1)

MCAL:

110285854

MPAH:

110313554

RNO:	308190(Cyp26c1)

MCOC:

ANU:

MUN:

CGE:

MAUA:

PROB:

PLEU:

MORG:

MFOT:

AAMP:

NGI:

HGL:

CPOC:

CCAN:

DORD:

DSP:

PLOP:

NCAR:

MMMA:

OCU:

OPI:

TUP:

GVR:

CFA:	608216(CYP26C1)

CLUD:

VVP:

VLG:

NPO:

AML:

UMR:

UAH:

UAR:

ELK:

LLV:

MPUF:

MNP:

MLK:

NVS:

ORO:

EJU:

ZCA:

MLX:

NSU:

LWW:

FCA:	101093894(CYP26C1)

PYU:

PCOO:

PBG:

PVIV:

LRUF:

PTG:

PPAD:

PUC:

AJU:

HHV:

BTA:	539048(CYP26C1)

BOM:

BIU:

BBUB:

BBIS:

CHX:

OAS:

BTAX:

ODA:

CCAD:

MBEZ:

SSC:

CFR:

CBAI:

CDK:

VPC:

BACU:

BMUS:

LVE:

OOR:

DLE:

PCAD:

PSIU:

NASI:

ECB:

EPZ:

EAI:

MYB:

MYD:

MMYO:

MLF:

PKL:

EFUS:

MNA:

DRO:

SHON:

AJM:

PDIC:

PHAS:

MMF:

PPAM:

HAI:

RFQ:

PALE:

PGIG:

PVP:

RAY:

MJV:

TOD:

SARA:

SETR:

LAV:

TMU:

ETF:

DNM:

MDO:

GAS:

SHR:

AFZ:

PCW:

OAA:

GGA:	423806(CYP26C1)

PCOC:

MGP:

CJO:

TPAI:

LMUT:

NMEL:

APLA:

ACYG:

CATA:

AFUL:

TGU:

LSR:

SCAN:

PMOA:

OTC:

PRUF:

GFR:

FAB:

OMA:

PHI:

PMAJ:

CCAE:

CCW:

CBRC:

ETL:

ZAB:

ACHL:

SVG:

MMEA:

HRT:

FPG:

FCH:

CLV:

NNI:

PLET:

ACUN:

TALA:

PADL:

AFOR:

ACHC:

HLE:

AGEN:

GCL:

CCRI:

CSTI:

CMAC:

MUI:

BREG:

FGA:

LDI:

MNB:

NNT:

SHAB:

DPUB:

PGUU:

ACAR:

CPEA:

CVF:

RTD:

CUCA:

TEO:

BRHI:

AAM:

AROW:

NPD:

DNE:

ASN:

AMJ:

CPOO:

GGN:

PSS:

CMY:

CCAY:

DCC:

CPIC:

TST:

CABI:

MRV:

ACS:

ASAO:

PVT:

SUND:

PBI:

PMUR:

CTIG:

TSR:

PGUT:

APRI:

PTEX:

NSS:

VKO:

PMUA:

PRAF:

ZVI:

HCG:

GJA:

STOW:

EMC:

XLA:	108696124(cyp26c1.L) 735026(cyp26c1.S)

XTR:	100489980(cyp26c1)

NPR:

RTEM:

BBUF:

BGAR:

MUO:

GSH:

DRE:	554036(cyp26c1)

SRX:	107717048 107750850

SANH:

107668609 107671105

SGH:	107553621 107583629

CCAR:

CAUA:

CGIB:

PTET:

LROH:

OMC:

PPRM:

RKG:

MAMB:

CIDE:

MASI:

TROS:

TDW:

MANU:

IPU:

IFU:

PHYP:

SMEO:

TFD:

TVC:

TRN:

AMEX:

CMAO:

EEE:

CHAR:

TRU:

TFS:

TNG:	GSTEN00034587G001

LCO:

NCC:

TBEN:

CGOB:

EMAC:

ELY:

EFO:

PLEP:

SLUC:

ECRA:

ESP:

PFLV:

GAT:

PPUG:

AFB:

CLUM:

PSWI:

MSAM:

SCHU:

CUD:

ALAT:

MZE:

ONL:

OAU:

OLA:

OML:

CSAI:

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:

PPRL:

CVG:

CTUL:

GMU:

NFU:

KMR:

ALIM:

NWH:

AOCE:

MCEP:

CSEM:

POV:

SSEN:

HHIP:

HSP:

PPLT:

SMAU:

LCF:

SDU:

SLAL:

XGL:

HCQ:

SSCV:

SBIA:

PEE:

PTAO:

BPEC:

MALB:

SJO:

SASA:

STRU:

OTW:	112253113 112255305

OMY:	110502548 110529957

OGO:	124038298 124041186

ONE:	115113165 115136320

OKI:	109888814 109899122

OKE:	118369799 118399531

SALP:

111952085 111978601

SNH:	120017805 120045910

CCLU:

121553685 121571587

ELS:

105010533

SFM:	108932780 108939510

PKI:	111853668 111858347

AANG:

LOC:

PSPA:

ARUT:

PSEX:

LCM:

CMK:

CPLA:

HOC:

LERI:

PMRN:

LRJ:

BFO:

BBEL:

SCLV:

HRF:

OED:

Reference

PMID:14532297 (CYP26C1)

Authors

Taimi M, Helvig C, Wisniewski J, Ramshaw H, White J, Amad M, Korczak B, Petkovich M

Title

A novel human cytochrome P450, CYP26C1, involved in metabolism of 9-cis and all-trans isomers of retinoic acid.

Journal

J Biol Chem 279:77-85 (2004)
DOI:10.1074/jbc.M308337200

Sequence

[hsa:340665]

Reference

PMID:29476041

Authors

Zhong G, Ortiz D, Zelter A, Nath A, Isoherranen N

Title

CYP26C1 Is a Hydroxylase of Multiple Active Retinoids and Interacts with Cellular Retinoic Acid Binding Proteins.

Journal

Mol Pharmacol 93:489-503 (2018)
DOI:10.1124/mol.117.111039

LinkDB

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