KEGG   ORTHOLOGY: K14336
Entry
K14336            Tight     KO                                     
Symbol
rlmA2
Name
23S rRNA (guanine748-N1)-methyltransferase [EC:2.1.1.188]
Reaction
R07233  S-adenosyl-L-methionine:rRNA (guanine-N1-)-methyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03009 Ribosome biogenesis
    K14336  rlmA2; 23S rRNA (guanine748-N1)-methyltransferase
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes
    K14336  rlmA2; 23S rRNA (guanine748-N1)-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.188  23S rRNA (guanine748-N1)-methyltransferase
     K14336  rlmA2; 23S rRNA (guanine748-N1)-methyltransferase
Ribosome biogenesis [BR:ko03009]
 Prokaryotic type
  rRNA modification factors
   23S rRNA modification factors
    K14336  rlmA2; 23S rRNA (guanine748-N1)-methyltransferase
Antimicrobial resistance genes [BR:ko01504]
 Gene variants
  Macrolide resistance genes
   23S rRNA methyltransferases
    K14336  rlmA2; 23S rRNA (guanine748-N1)-methyltransferase
Other DBs
GO: 0052912
Genes
AG: CAB37345(erm(32))
Reference
PMID:15046978
  Authors
Douthwaite S, Crain PF, Liu M, Poehlsgaard J
  Title
The tylosin-resistance methyltransferase RlmA(II) (TlrB) modifies the N-1 position of 23S rRNA nucleotide G748.
  Journal
J Mol Biol 337:1073-7 (2004)
DOI:10.1016/j.jmb.2004.02.030
  Sequence
[ag:CAB37345]
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