KEGG   ORTHOLOGY: K17691
Entry
K17691            Tight     KO                                     
Symbol
CYP3A7
Name
cytochrome P450 family 3 subfamily A7 [EC:1.14.14.1]
Pathway
map00140  Steroid hormone biosynthesis
map00830  Retinol metabolism
map01100  Metabolic pathways
map05204  Chemical carcinogenesis - DNA adducts
Reaction
R03408  
R08390  
R08392  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    K17691  CYP3A7; cytochrome P450 family 3 subfamily A7
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K17691  CYP3A7; cytochrome P450 family 3 subfamily A7
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    K17691  CYP3A7; cytochrome P450 family 3 subfamily A7
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K17691  CYP3A7; cytochrome P450 family 3 subfamily A7
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     K17691  CYP3A7; cytochrome P450 family 3 subfamily A7
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP3 family
   K17691  CYP3A7; cytochrome P450 family 3 subfamily A7
Genes
HSA: 100861540(CYP3A7-CYP3A51P) 1551(CYP3A7)
PTR: 737263(CYP3A7)
PPS: 100967578 100975985(CYP3A67)
GGO: 101147362 115935323
PON: 100435763 100436403
NLE: 115830387
HMH: 116810916
MCC: 100144394(CYP3A7)
MCF: 102144626 102145015(CYP3A7)
MTHB: 126950476
MNI: 105497398
CSAB: 103246767 103246772(CYP3A7)
CATY: 105584398
PANU: 100997059
TGE: 112621196
TFN: 117072036
 » show all
Reference
PMID:2722762
  Authors
Komori M, Nishio K, Ohi H, Kitada M, Kamataki T
  Title
Molecular cloning and sequence analysis of cDNA containing the entire coding region for human fetal liver cytochrome P-450.
  Journal
J Biochem 105:161-3 (1989)
DOI:10.1093/oxfordjournals.jbchem.a122632
  Sequence
[hsa:1551]
Reference
  Authors
McArthur AG, Hegelund T, Cox RL, Stegeman JJ, Liljenberg M, Olsson U, Sundberg P, Celander MC
  Title
Phylogenetic analysis of the cytochrome P450 3 (CYP3) gene family.
  Journal
J Mol Evol 57:200-11 (2003)
DOI:10.1007/s00239-003-2466-x
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