KEGG   ORTHOLOGY: K21220
Entry
K21220                      KO                                     
Symbol
thiN
Name
thiamine-phosphate diphosphorylase [EC:2.5.1.3]
Pathway
map00730  Thiamine metabolism
map01100  Metabolic pathways
map01240  Biosynthesis of cofactors
Module
M00896  Thiamine biosynthesis, archaea, AIR (+ NAD+) => TMP/TPP
Reaction
R03223  2-methyl-4-amino-5-hydroxymethylpyrimidine-diphosphate:4-methyl-5-(2-phosphoethyl)-thiazole 2-methyl-4-aminopyridine-5-methenyltransferase
R10712  2-methyl-4-amino-5-hydroxymethylpyrimidine-diphosphate:2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate 2-methyl-4-aminopyrimidine-5-methenyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00730 Thiamine metabolism
    K21220  thiN; thiamine-phosphate diphosphorylase
Enzymes [BR:ko01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.3  thiamine phosphate synthase
     K21220  thiN; thiamine-phosphate diphosphorylase
Other DBs
COG: COG1992
GO: 0004789
Genes
MTH: MTH_861
MMG: MTBMA_c12580(thiD2)
MWO: MWSIV6_1237(thiN)
MTEE: MTTB_05180
METC: MTCT_0777
METE: tca_00828(thiDN)
METZ: METMT2_0931
METK: FVF72_07240
MTHM: FZP57_05880
METJ: FZP68_00325
METH: MBMB1_0679
MFC: BRM9_1515(thiD2)
MCUB: MCBB_0689(thiN)
MFV: Mfer_1268
MBAR: MSBR2_0837
MBAK: MSBR3_0418
MTHR: MSTHT_0630
MTHE: MSTHC_0090
MHOR: MSHOH_2017
MHU: Mhun_1490
MLA: Mlab_1227
MEMA: MMAB1_1466
MPI: Mpet_1285
MBN: Mboo_1394
STO: STK_22090
SSO: SSO0039
SOL: Ssol_1022
SSOA: SULA_1054
SSOL: SULB_1056
SSOF: SULC_1055
SCAS: SACC_32260
SAI: Saci_2353
SID: M164_2082
SII: LD85_2343
SIH: SiH_2021
SIR: SiRe_1955
SIC: SiL_1929
MSE: Msed_0564
MEMJ: MJ1HA_0671
MCN: Mcup_1531
AHO: Ahos_0042
ACIH: HS5_12980
CSTY: KN1_06220
STEP: IC006_1999
SAHS: HS7_00190
PAS: Pars_0919
TPE: Tpen_1312
 » show all
Reference
  Authors
Morett E, Korbel JO, Rajan E, Saab-Rincon G, Olvera L, Olvera M, Schmidt S, Snel B, Bork P
  Title
Systematic discovery of analogous enzymes in thiamin biosynthesis.
  Journal
Nat Biotechnol 21:790-5 (2003)
DOI:10.1038/nbt834
  Sequence
[mth:MTH_861]
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