KEGG   ORTHOLOGY: K21533
Entry
K21533                      KO                                     
Symbol
vIL10
Name
Herpesviridae/Poxviridae viral interleukin 10
Pathway
map04061  Viral protein interaction with cytokine and cytokine receptor
map05163  Human cytomegalovirus infection
Network
nt06167  Human cytomegalovirus (HCMV)
nt06518  JAK-STAT signaling
  Element
N00416  HCMV vIL10 to IL10-JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04061 Viral protein interaction with cytokine and cytokine receptor
    K21533  vIL10; Herpesviridae/Poxviridae viral interleukin 10
 09160 Human Diseases
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    K21533  vIL10; Herpesviridae/Poxviridae viral interleukin 10
 09180 Brite Hierarchies
  09185 Viral protein families
   03200 Viral proteins
    K21533  vIL10; Herpesviridae/Poxviridae viral interleukin 10
Viral proteins [BR:ko03200]
 dsDNA viruses
  Epstein-Barr virus (Human herpesvirus 4)
   K21533  vIL10; Herpesviridae/Poxviridae viral interleukin 10
Viral network perturbations [br03223.html]
 Cytokine-cytokine receptor interaction
  K21533
Genes
VG: 1461021(E7) 22647525(SB87_gp125) 23104216(E7) 2947681(ORFVgORF127) 2947853(BPSVgORF127) 2949786(CeHV15gBCRF1) 33349955(CGV03_gp114) 3783689(BCRF1) 3837434(AWE45_gp02) 40524759(FK808_gp4) 5176163(HHV4tp2_gp04) 5228362(GTPV_gp003) 65099634(BCRF1) 80540021(BCRF1) 921630(LSDV005) 944684(SPPV_03)
Reference
PMID:2161559
  Authors
Moore KW, Vieira P, Fiorentino DF, Trounstine ML, Khan TA, Mosmann TR
  Title
Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI.
  Journal
Science 248:1230-4 (1990)
DOI:10.1126/science.2161559
  Sequence
[vg:3783689]
Reference
PMID:9310490
  Authors
Zeidler R, Eissner G, Meissner P, Uebel S, Tampe R, Lazis S, Hammerschmidt W
  Title
Downregulation of TAP1 in B lymphocytes by cellular and Epstein-Barr virus-encoded interleukin-10.
  Journal
Blood 90:2390-7 (1997)
  Sequence
[vg:3783689]
LinkDB

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