KEGG   MODULE: M00019
Entry
M00019            Pathway   Module                                 
Name
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
Definition
K01652+(K01653,K11258) K00053 K01687 K00826
Diagram
M00019

Orthology
acetolactate synthase [EC:2.2.1.6] [RN:R00226 R08648]
K00053  
ketol-acid reductoisomerase [EC:1.1.1.86] [RN:R05071 R04440 R04439 R05069 R05068]
K01687  
dihydroxy-acid dehydratase [EC:4.2.1.9] [RN:R04441 R05070]
K00826  
branched-chain amino acid aminotransferase [EC:2.6.1.42] [RN:R01214 R02199]
Class
Pathway modules; Amino acid metabolism; Branched-chain amino acid metabolism
Pathway
map00290  Valine, leucine and isoleucine biosynthesis
map00770  Pantothenate and CoA biosynthesis
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
Compound
C00022  Pyruvate
C06010  (S)-2-Acetolactate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00109  2-Oxobutanoate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C00671  (S)-3-Methyl-2-oxopentanoic acid
C00407  L-Isoleucine
RModule
RM033  Branched-chain addition (branched-chain amino acid synthesis)
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